Nootropics Depot's Erinamax Sets Industry Benchmark with Market-Leading Erinacine A Standardization

News provided by

Oct 09, 2025, 11:41 ET

TEMPE, Ariz., Oct. 9, 2025 /PRNewswire/ -- Nootropics Depot, a pioneer in innovative dietary supplements, announces new results from independent market testing of its Erinamax Lion's Mane mycelium capsules. Independent laboratory analysis indicates that Erinamax is standardized to 2.5 mg of erinacine A per capsule, providing a consistent serving of this important bioactive compound.

Erinamax is the only Lion’s Mane supplement standardized to a clinically meaningful dose of erinacine A, delivering over 32 times more of this neuroactive compound than competing products based on Q2 2025 market lab testing.

This milestone is the result of ten years of research and methodical laboratory development, including the use of proprietary liquid bioreactor cultivation techniques and the creation of a reference standard for erinacine A. Erinamax is manufactured from pure, freeze-dried Lion's Mane mycelium using liquid cultivation without grain substrate, which helps maintain product purity and consistency. Every batch is analyzed at ISO-accredited facilities utilizing Ultra-Performance Liquid Chromatography (UPLC) to quantify erinacine A content, ensuring product quality and reliability.

These efforts set new standards for transparency and quality assurance in the mushroom supplement sector. Recent evaluations of various Lion's Mane supplements suggest that many products may not be standardized to measurable levels of erinacine A, highlighting the importance of robust verification and accurate labeling. Erinamax aims to raise benchmarks in the category through its commitment to standardized testing and analysis.

Erinacine A is recognized as a key bioactive compound in Lion's Mane mycelium. Standardizing to Erinacine A may help support cognitive function, memory, and overall nerve health. Most other Lion's Mane supplements may offer little or undetectable erinacine A content, making standardization essential for reliability and consumer confidence. Erinamax provides a consistent, lab-verified amount of erinacine A in every serving.

Paul Eftang, CEO of Nootropics Depot, stated, "This development reflects our dedication to quality, transparency, and scientific progress. With Erinamax, we strive to offer a product that is supported by rigorous lab validation. Our mission is to help people make informed choices about supplements for cognitive and overall wellness."

Scientific Research and Ongoing Exploration

Multiple peer-reviewed studies have demonstrated the therapeutic promise of erinacine A. A landmark double-blind, placebo-controlled clinical trial published in Frontiers in Aging Neuroscience showed that daily supplementation with erinacine A-enriched Lion's Mane mycelium (EAHE) for 49 weeks led to significant improvements in cognitive assessments—including Mini-Mental State Examination (MMSE) scores and Instrumental Activities of Daily Living (IADL) scores—plus better visual contrast sensitivity in participants with mild Alzheimer's Disease. The study further identified a stabilization of key biomarkers (calcium, albumin, apolipoprotein E4, hemoglobin, and brain-derived neurotrophic factor) in the EAHE group, with no serious adverse events observed.

Additional research published in Journal of Ethnopharmacology and Neuropharmacology has shown that erinacine A delays age-related brain degeneration, improves learning and memory in animal models, and promotes neurogenesis—while also demonstrating safety and tolerability for long-term use. Standardized erinacine A content has been linked to reduced amyloid-β plaque formation—critical in Alzheimer's Disease progression—and increased nerve growth factor activity. While ongoing research continues to explore these benefits, dietary supplements like Erinamax are not intended to diagnose, treat, cure, or prevent any disease.

The scientific community's interest in Lion's Mane and erinacine A supports continued research and product development. Supplement users may find these discussions helpful when considering options for brain health and wellness support.

For those interested in the research on Lion's Mane mycelium and erinacine A, the following studies have been published in the scientific literature:

Erinamax is reviewed by experts on Nootropics Depot's Scientific Advisory Board. The product may help support overall cognitive performance and nerve health in adults of all backgrounds. Erinamax delivers a consistent serving of standardized erinacine A in every capsule, confirmed through independent laboratory testing for quality and integrity.

Nootropics Depot is a leading supplement company setting benchmark standards for quality and transparency in the industry. Founded in 2013, Nootropics Depot's mission has been to educate consumers on the science behind dietary supplements, and to advance the lab testing and quality control standards of the industry. Their stance is that consumers should be able to trust the products they buy, and that the brands selling those products have a duty to ensure they are using modern validated science. Nootropics Depot offers a wide range of high-quality cognitive enhancement and general health supplements. The company's commitment to quality and transparency is evident in their rigorous testing procedures, easily accessible Certificates of Analysis (COAs), and lab testing results available on every product page. In addition, they have formed a Scientific Advisory Board with board certified doctors, PhD researchers, and botanists to ensure that consumers can trust that scientific rigor is being upheld in everything they do. Nootropics Depot's newly redesigned website features a user-friendly interface, and includes an innovative quiz to help beginners find the right supplements for their needs. With partnerships with third-party labs, and collaboration with the Future Nutra Foundation, Nootropics Depot continues to push the boundaries of supplement quality and consumer education. For more information about Nootropics Depot's products and their commitment to transparency, visit nootropicsdepot.com.

Media Contact
Michael Packman
Marketing Manager
Nootropics Depot
[email protected]

SOURCE Nootropics Depot