Obstructive Sleep Apnea Market to Grow Rapidly at a CAGR of 14.7% by 2032, Estimates DelveInsight

The obstructive sleep apnea market dynamics are anticipated to change in the coming years owing to the expected approval of emerging therapies focused on treating obstructive sleep apnea during the forecast period of 2023‒2032. There are presently a few key players in the obstructive sleep apnea market, including Apnimed, Eli Lilly and Company, and others.

LAS VEGAS, May 2, 2023 /PRNewswire/ -- DelveInsight's Obstructive Sleep Apnea Market Insights report includes a comprehensive understanding of current treatment practices, obstructive sleep apnea emerging drugs, market share of individual therapies, and current and forecasted market size from 2019 to 2032, segmented into 7MM [the United States, the EU-4 (Italy, Spain, France, and Germany), the United Kingdom, and Japan].

Key Takeaways from the Obstructive Sleep Apnea Market Report

• As per DelveInsight analysis, the obstructive sleep apnea market size in the 7MM was approximately USD 408 million in 2022.
• According to the assessment done by DelveInsight, the estimated total prevalent obstructive sleep apnea cases in the 7MM were approximately 24 million in 2022. 
• Globally, leading obstructive sleep apnea companies such as Apnimed, Eli Lilly and Company, Therapix Biosciences, Bioprojet Pharma, Axsome Therapeutics/ Jazz Pharmaceuticals and others are developing novel obstructive sleep apnea drugs that can be available in the obstructive sleep apnea market in the coming years.
• The promising obstructive sleep apnea therapies in the pipeline include AD109, Tirzepatide, and others.
• In January 2023, Aculys Pharma initiated a Phase III trial of Pitolisant treating patients with EDS associated with OSA in Japan.

Discover which therapies are expected to grab the major obstructive sleep apnea market share @ Obstructive Sleep Apnea Market Report

Obstructive Sleep Apnea Overview

Obstructive sleep apnea, also known as obstructive sleep apnea-hypopnea, is a sleeping disorder that causes the airflow to stop or drastically decrease while breathing is attempted. It is the most common type of sleep-disordered breathing and is characterized by recurring bouts of upper airway collapse as a person sleeps. Common obstructive sleep apnea symptoms include inexplicable daytime tiredness, restless sleep, and loud snoring. Morning headaches; sleeplessness; difficulty concentrating; and mood changes such as impatience, anxiety, melancholy, and others are less prevalent obstructive sleep apnea symptoms.

Sleep-related reduced ventilatory drive and neuromuscular risk factors, in combination with anatomic risk factors, are expected to play a substantial role in upper airway blockage during sleep. Obstructive sleep apnea is diagnosed when a patient has recurring episodes of partial or entire collapse of the upper airway during sleep, resulting in apneas or hypopneas respectively. The criteria for defining an apnea or a hypopnea differ.

Obstructive Sleep Apnea Epidemiology Segmentation

DelveInsight estimates that there were approximately 24 million prevalent cases of obstructive sleep apnea in the 7MM in 2022.

According to DelveInsight estimates, the United States contributed to the largest diagnosed prevalent population of obstructive sleep apnea, acquiring ~53% of the 7MM in 2022. Whereas EU4 and the UK, and Japan accounted for around 27% and 20% of the total population share, respectively, in 2022.

The obstructive sleep apnea market report proffers epidemiological analysis for the study period 2019–2032 in the 7MM segmented into:

• Total Obstructive Sleep Apnea Diagnosed Prevalent Cases
• Obstructive Sleep Apnea Gender-specific Diagnosed Prevalent Cases
• Obstructive Sleep Apnea Age-specific Diagnosed Prevalent Cases
• Obstructive Sleep Apnea Severity-specific Diagnosed Cases

Download the report to understand which factors are driving obstructive sleep apnea epidemiology trends @ Obstructive Sleep Apnea Epidemiological Insights

Obstructive Sleep Apnea Treatment Market 

Obstructive sleep apnea is often treated with weight loss and exercise, CPAP therapy (the first line of obstructive sleep apnea treatment), bilevel positive airway pressure (BPAP) equipment (if CPAP therapy is ineffective), and surgery. EDS, the most usually related indication, can be treated with PROVIGIL/MODIODAL (modafinil), NUVIGIL (armodafinil), SUNOSI (solriamfetol), Pitolisant, and certain other off-label medications. PROVIGIL (modafinil), which Cephalon introduced in 1999, is used to treat excessive drowsiness caused by narcolepsy, obstructive sleep apnea, and shift work disorder. Provigil is approved for the treatment of EDS associated with narcolepsy in over 30 countries outside the United States, including France, the United Kingdom, Ireland, Italy, and Germany, under several trade names.

NUVIGIL (armodafinil), the R-isomer of modafinil, was introduced by Cephalon in June 2009 to treat excessive drowsiness associated with narcolepsy, obstructive sleep apnea, and shift work disorder. The US FDA authorized SUNOSI (solriamfetol) in March 2019 for EDS associated with narcolepsy or obstructive sleep apnea. Sunosi is the first and only FDA-approved dual-acting dopamine and norepinephrine reuptake inhibitor to improve wakefulness in individuals with EDS and narcolepsy or obstructive sleep apnea.

The European Medicines Agency (EMA) approved OZAWADE (pitolisant) for the treatment of EDS in adult OSA patients in 2021. In 2016, the European Commission authorized it as a treatment for narcolepsy with or without cataplexy. In January 2023, Aculys Pharma began a Phase III trial of Pitolisant in Japan, treating patients with EDS accompanied by obstructive sleep apnea.

To know more about obstructive sleep apnea treatment guidelines, visit @ Obstructive Sleep Apnea Management 

Obstructive Sleep Apnea Therapies and Key Companies

• AD109: Apnimed
• Tirzepatide: Eli Lilly and Company
• AD113: Apnimed
• SUNOSI (Solriamfetol): Axsome Therapeutics/Jazz Pharmaceuticals
• OZAWADE (Pitolisant): Bioprojet Pharma

Learn more about the FDA-approved drugs for obstructive sleep apnea @ Drugs for Obstructive Sleep Apnea Treatment 

Obstructive Sleep Apnea Market Dynamics

The dynamics of the obstructive sleep apnea market are expected to change in the coming years. The tremendous growth of the sleep apnea diagnosis market over the last decade can be linked to the constant advancement of sleep apnea therapy utilization. Moreover, obstructive sleep apnea is poorly understood; implementing programs such as "sleep awareness week" by various organizations and government agencies might boost the diagnosis rate and obstructive sleep apnea treatment.

Furthermore, the biggest issue and unmet need in obstructive sleep apnea treatment are that no drug is approved for direct obstructive sleep apnea treatment. If approved, the key competitive factors that may affect the success of these products and any other product candidates that have yet to reach the obstructive sleep apnea market are likely to be efficacy, safety, convenience, cost, the availability of generic competition, and reimbursement from government and other third-party payers.

However, several factors are impeding the growth of the obstructive sleep apnea market. Patients lose interest in therapy due to the high expense and concern associated with it, which is expected to stifle therapeutic obstructive sleep apnea growth. Some medications in their later stages have failed, indicating the possibility of current new drugs failing. In addition, the undiagnosed, unreported cases and the unawareness about the disease may also impact the obstructive sleep apnea market growth.

Scope of the Obstructive Sleep Apnea Market Report

• Therapeutic Assessment: Obstructive Sleep Apnea current marketed and emerging therapies
• Obstructive Sleep Apnea Market Dynamics: Attribute Analysis of Emerging Obstructive Sleep Apnea Drugs 
• Competitive Intelligence Analysis: SWOT analysis and Market entry strategies
• Unmet Needs, KOL's Views, Analyst's Views, Obstructive Sleep Apnea Market Access and Reimbursement

Discover more about obstructive sleep apnea drugs in development @ Obstructive Sleep Apnea Clinical Trials

Table of Contents

Related Reports

Obstructive Sleep Apnea Epidemiology Forecast

Obstructive Sleep Apnea Epidemiology Forecast – 2032 report delivers an in-depth understanding of the disease, historical and forecasted obstructive sleep apnea epidemiology in the 7MM, i.e., the United States, EU5 (Germany, Spain, Italy, France, and the United Kingdom), and Japan.

Obstructive Sleep Apnea Pipeline

Obstructive Sleep Apnea Pipeline Insight – 2023 report provides comprehensive insights about the pipeline landscape, pipeline drug profiles, including clinical and non-clinical stage products, and the key obstructive sleep apnea companies, including Apnimed, Therapix Biosciences, Axsome Therapeutics/ Jazz Pharmaceuticals among others.

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SOURCE DelveInsight Business Research, LLP