TheWell Bioscience Launches VitroGel® NEURON, a First-Of-Its-Kind Synthetic Hydrogel for Superior 3D, 2D Neuronal Cell Culture and Beyond

MONMOUTH JUNCTION, N.J., Sept. 9, 2025 /PRNewswire/ -- TheWell Bioscience Inc., a leader in advanced 3D cell culture platform for precision medicine, cell therapy and biomanufacturing, announces the launch of VitroGel® NEURON, a groundbreaking synthetic and xeno-free hydrogel specifically engineered to overcome the limitations of animal-derived matrices by supporting both 3D and 2D neuronal cell culture and serving as an injectable carrier for in vivo delivery.  This robust platform provides a defined, reproducible, and scalable environment for neuronal growth, differentiation, and network formation.

Unlike traditional animal-based extracellular matrices, which are mainly confined to support 2D neuron attachment, VitroGel® NEURON efficiently supports both 3D and 2D neuronal cell culture and in vivo applications.   Engineered to promote robust cell–cell and cell–matrix interactions, VitroGel® NEURON is a ready-to-use synthetic system that supports a wide range of neuronal cell types for neurodevelopmental and neurodegenerative disease modeling, drug screening, and neurotoxicity testing. Its unique injectable properties also position VitroGel® NEURON as a powerful injectable carrier for neuron-based cell therapy, spinal cord injury repair, and other regenerative medicine applications.

"After more than five years of dedicated R&D, we are proud to introduce the xeno-free VitroGel® NEURON. To our knowledge, this is the first commercial synthetic hydrogel on the market that can effectively support 3D neuron outgrowth and network formation across a wide spectrum of applications," said John Huang, Ph.D., CEO of TheWell Bioscience Inc. "We believe this groundbreaking technology will not only provide a reliable and physiologically relevant platform for developing diverse 3D neuronal cell models, but also as a delivery system to advance cell therapy and regenerative medicine to the next level."

The launch of VitroGel® NEURON marks a pivotal step in TheWell Bioscience's roadmap to shape the future of 3D cell culture for biomedical applications. By eliminating the variability of traditional animal-derived matrices, VitroGel® NEURON not only delivers more consistent neuronal cell culture, clinically translatable results, but also supports the global shift toward reducing reliance on animal models in drug development. This powerful platform opens new doors for breakthroughs in neurobiology, disease modeling, regenerative medicine, and neuropharmacology.

VitroGel® NEURON is available for research use. For more information, visit TheWell Bioscience's website product page at www.thewellbio.com or contact [email protected].

About TheWell Bioscience Inc.

TheWell Bioscience Inc. is a pioneering biotechnology company dedicated to advancing 3D cell culture and tissue engineering through the innovative xeno-free VitroGel® hydrogel platforms. The VitroGel® product line provides researchers with reliable, customizable, and translationally relevant solutions for drug discovery, regenerative medicine, and disease modeling.

Media Contact:
Kyra Baricaua
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SOURCE TheWell Bioscience Inc.