World Precision Instruments Launches EVOM™ Auto ElectroZ, Bringing Advanced Cellular Insights to Automated Barrier Measurements

New technology combines simplicity of TEER with the analytical power of multi-frequency impedance spectroscopy, enabling researchers to learn more from the same cells, using the same workflows.

SARASOTA, Fla., Nov. 9, 2026 /PRNewswire/ -- World Precision Instruments (WPI), a global provider of precision instrumentation for life science research, announces the launch of EVOM™ Auto ElectroZ, expanding its established automated transepithelial/endothelial electrical resistance (TEER) measurement platform with advanced electrochemical impedance spectroscopy (EIS) capabilities.

For decades, researchers have relied on TEER to evaluate the integrity of cellular barriers. Now, EVOM™ Auto ElectroZ takes these measurements further, enabling researchers to acquire data associated with cellular growth, maturation, morphology, and polarization, all within familiar, commercially available Transwell culture formats.

"TEER has long been an essential tool for understanding cellular barrier function, but resistance doesn't tell the whole story, " said Mark Rutledge, Chief Executive Officer at World Precision Instruments. "With ElectroZ, we're giving researchers the ability to explore a much richer picture of their cells without changing the models or workflows that they already trust. It's about making advanced cellular analysis more accessible while preserving the biological relevance of the model and experiment."

Beyond TEER: More Information from Every Measurement

Traditional TEER measurement provides a straightforward assessment of barrier integrity by measuring the electrical resistance across a cell layer at 12.5 Hz. ElectroZ expands this capability by measuring impedance across multiple frequencies from 2 Hz to 100 kHz, capturing both resistive and capacitive properties of living cells.

In a measurement that often takes less than 20 seconds, ElectroZ collects a rich impedance dataset and automatically calculates key parameters:

• TEER Cellular: Resistance attributable to the cell layer itself, separating it from background contributions of media, inserts, electrodes, or matrix proteins secreted by the cells. With ElectroZ, cellular resistance can be measured in a single sample, , eliminating the need for separate blank measurements and manual background subtraction.
• TEER Total: Measures the total resistance of the cell layer and background contributions.
• Transepithelial Capacitance (TEC): Provides insights into cellular growth, cell size, morphology, maturation, differentiation status, and cell health.
• Tau Ratio: A novel impedance-derived parameter designed to characterize electrical asymmetry between the apical and basolateral membranes, offering a new approach to investigating cellular polarity.

ElectroZ brings the power of impedance data sets to the simplicity of TEER measurement, unlocking richer insights from familiar workflows. Together, these measurements allow researchers to explore changes in cellular electrical properties throughout an experiment, from initial cell seeding and growth through barrier formation and maturation, and during drug exposure and recovery.

Advanced Impedance Analysis Without Specialized Culture Plates

A key advantage of EVOM™ Auto ElectroZ is its compatibility with commercially available transwell plates. Unlike conventional impedance systems that require cells to grow directly on specialized electrodes integrated surfaces, ElectroZ uses interchangeable electrode arrays, to perform measurements in established transwell formats. This distinction is particularly important for researchers studying physiologically relevant tissue barriers, where access to both the apical and basolateral compartments supports polarized cell cultures, multicellular models, and directional transport studies. Applications include blood–brain and blood–retinal barriers, intestinal and airway epithelium, kidney and placental models, and other epithelial and endothelial tissues. Because measurements are non-destructive, researchers can repeatedly characterize living cultures while preserving them for complementary analyses, including permeability assays, imaging, and immunocytochemistry.

The Simplicity of TEER. The Power of EIS. One Automated Platform.

EVOM™ Auto ElectroZ combines advanced measurement capabilities of EIS with the convenience of the automated platform that has been well adopted across academic labs and pharmaceutical workflows. Researchers can choose between EVOM Auto Classic for fast, familiar TEER measurements or ElectroZ for multi-frequency impedance analysis and expanded biological characterization of the cells.

Interchangeable electrode arrays, automatic electrode head detection, programmable measurement schedules, and automated electrode rinsing simplify experimental workflows. Built-in alignment detection, crash protection, and user-defined measurement thresholds further support reliable operation and routing quality control.

For researchers seeking deeper analytics, ElectroZ software provides customizable frequency profiles, automated equivalent-circuit selection and modeling, and access to raw impedance data.

Expanding the Possibilities for Cell-Based Research

From drug discovery and disease modeling to tissue engineering and cell culture quality control, EVOM™ Auto ElectroZ brings advanced characterization to established barrier research workflows.

By combining traditional TEER and multi-frequency impedance on one automated platform, WPI enables researchers to move seamlessly from routine barrier assessment to deeper cellular analysis without requiring separate instrumentation or proprietary electrode-integrated cultureware.

Same cells. Same workflows. More Insights.

EVOM™ Auto ElectroZ is now available from World Precision Instruments. For additional information, visit wpiinc.com/eis.

About WPI

WPI provides precision instruments, laboratory equipment, and consumables to researchers around the world. For nearly 60 years, WPI has supported advances in neuroscience, physiology, cell biology, ophthalmology, and other life science disciplines through innovative tools designed to improve experimental outcomes, both expediting and simplifying life science discoveries.

SOURCE World Precision Instruments, Inc.