Wyss Institute collaborates with ReWalk Robotics to develop wearable exosuits for patients with limited mobility

"This is a very exciting day for the soft exosuit technology," said Conor Walsh, Ph.D., who is a Core Faculty Member at the Wyss Institute, the John L. Loeb Associate Professor of Engineering and Applied Sciences at Harvard John A. Paulson School of Engineering and Applied Sciences, and Founder of the Harvard Biodesign Lab. "ReWalk brings commercialization expertise and experience in the area of wearable robotics and complements our translation-focused research. Ultimately this agreement paves the way for this technology to make its way to patients."

The soft exosuit – which is a soft wearable robot that is the first of its kind – was developed at the Wyss Institute by Walsh and his team through extensive prototyping that included the involvement of roboticists, mechanical and biomechanical engineers, apparel designers, and software engineers. Walsh's collaborators also include Terry Ellis and Ken Holt, both faculty members at Boston University's Department of Physical Therapy & Athletic Training.

"What makes the soft exosuit's development so unique is the extreme multi-disciplinary nature of the work. In addition to our varied technical expertise as a team, our research with voluntary study participants has been central to our understanding of how we need to design and build these exosuits," said Kathleen O'Donnell, who has been leading the team at the Wyss Institute with Walsh. Over the course of its development, the soft exosuit has been the catalyst for entirely new forms of functional textiles, flexible power systems and control strategies that integrate the suit and its wearer in ways that mimic the natural biomechanics of the human musculoskeletal system.

"There is a great need in the health care system for lightweight, lower-cost wearable exoskeleton designs to support stroke patients, individuals diagnosed with multiple sclerosis and senior citizens who require mechanical mobility assistance. This collaboration will help create the next generation of exoskeleton systems, making life-changing technology available to millions of consumers across a host of patient populations," said Larry Jasinski, CEO of ReWalk.

Using form-fitting, fabric-based designs that are lightweight and non-restrictive, the Wyss Institute's soft exosuit uses compact, powerful actuators packaged in a belt to provide assistance to the wearer's legs in a physiologically relevant manner. These enhanced movements have the potential to assist wearers in walking with greater stability and metabolic efficiency, which could prevent injury and reduce fatigue.

Most currently-marketed exoskeletons are rigid systems providing structural support and large assistance to patients with extremely severe movement disabilities, for example due to spinal cord injuries. For many stroke, MS, and elderly patients who can move partially on their own, the assistive and elegant movements of the lighter weight, flexible, soft exosuit could be used to overcome mobility limitations in their lower extremities. Currently in the United States, there are an estimated 3 million stroke patients and 400,000 MS patients who are suffering from limited mobility due to lower limb disabilities.

"The soft exosuit is a wonderful example of how understanding how living systems work – in this case the movement and control of the human body – can inspire design of an innovative wearable robotic technology that has the potential to change the future of medicine. It is also tremendously gratifying to see how this collaboration between ReWalk Robotics and Conor Walsh's lab has developed and been nurtured at the Wyss Institute, given our focus on translating technologies from the laboratory and into the marketplace," said Wyss Institute Founding Director Donald Ingber, M.D., Ph.D., who is the Judah Folkman Professor of Vascular Biology at Harvard Medical School and the Vascular Biology Program at Boston Children's Hospital, and also Professor of Bioengineering at the Harvard John A. Paulson School of Engineering and Applied Sciences.

Harvard's Office of Technology Development worked with the Wyss Institute to structure this collaboration with ReWalk, which includes a license for intellectual property and funding for the continued development at the Institute, towards bringing this new wearable therapeutic device into the marketplace. Additional funding for the Wyss Institute's exosuit came from the Defense Advanced Research Projects Agency's Warrior Web program, which seeks to develop technologies to mitigate musculoskeletal injuries among military Service members while improving performance.

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PRESS CONTACTS

Wyss Institute for Biologically Inspired Engineering at Harvard University
Mary Tolikas, [email protected], +1 617-432-7733

Harvard University's Office of Technology Development
Caroline Perry, [email protected], +1 617-495-4157

ReWalk Robotics
Jennifer Wlach, [email protected], +1 202-261-4000

MULTIMEDIA CONTACT
Wyss Institute for Biologically Inspired Engineering at Harvard University
Seth Kroll, [email protected], +1 617-432-7758

The Wyss Institute for Biologically Inspired Engineering at Harvard University (http://wyss.harvard.edu) uses Nature's design principles to develop bioinspired materials and devices that will transform medicine and create a more sustainable world. Wyss researchers are developing innovative new engineering solutions for healthcare, energy, architecture, robotics, and manufacturing that are translated into commercial products and therapies through collaborations with clinical investigators, corporate alliances, and formation of new startups. The Wyss Institute creates transformative technological breakthroughs by engaging in high risk research, and crosses disciplinary and institutional barriers, working as an alliance that includes Harvard's Schools of Medicine, Engineering, Arts & Sciences and Design, and in partnership with Beth Israel Deaconess Medical Center, Brigham and Women's Hospital, Boston Children's Hospital, Dana-Farber Cancer Institute, Massachusetts General Hospital, the University of Massachusetts Medical School, Spaulding Rehabilitation Hospital, Boston University, Tufts University, Charité – Universitätsmedizin Berlin, University of Zurich and Massachusetts Institute of Technology.

Harvard University's Office of Technology Development (http://otd.harvard.edu) promotes the public good by fostering innovation and translating new inventions made at Harvard University into useful products that are available and beneficial to society. Our integrated approach to technology development comprises sponsored research and corporate alliances, intellectual property management, and technology commercialization through venture creation and licensing. Harvard OTD also manages the Blavatnik Biomedical Accelerator and the Physical Sciences & Engineering Accelerator.

ReWalk Robotics Ltd. (http://rewalk.com) develops, manufactures and markets wearable robotic exoskeletons for individuals with spinal cord injury. Our mission is to fundamentally change the quality of life for individuals with lower limb disability through the creation and development of market leading robotic technologies. Founded in 2001, ReWalk has headquarters in the U.S., Israel and Germany.

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SOURCE Wyss Institute for Biologically Inspired Engineering at Harvard University