Altos Therapeutics Receives Second Issued Patent Covering Novel Dopamine D2/D3 Antagonists for the Treatment of Gastrointestinal Diseases

Jan 09, 2015, 15:44 ET from Altos Therapeutics, LLC

LOS ALTOS, Calif., Jan. 9, 2015 /PRNewswire/ -- Altos Therapeutics, LLC announced today that the Mexican Institute of Industrial Property has issued Patent Number 323020 titled, "D2 Antagonists, Methods of Synthesis and Methods of Use".  The patent broadly and specifically covers the company's dopamine D2/D3 drug candidates, their pharmaceutical compositions, and their use to treat a number of important gastrointestinal conditions in humans, such as gastroparesis.

The issuance of the Mexican patent follows the previous issuance by the United States Patent and Trademark Office of the patent numbered 8691836, covering a similar set of broad claims.

"The issuance of the patent in Mexico, in addition to that in the USA marks a significant milestone in establishing extended intellectual property protection for our lead compounds" stated Roger Whiting, Ph.D., President and CEO of Altos Therapeutics.  These compounds are currently being developed to meet unmet clinical needs in conditions in which D2 and D3 dopamine receptors have been shown to play key roles. Patent protection in the USA and Mexico should extend to until at least 2031 under present laws and is also pending internationally in other key countries.

About Dopamine D2/D3 Receptor Antagonists

D2/D3 receptor antagonists uniquely have a multimodal therapeutic effect including stimulating gastric motility, normalizing gastric rhythm via actions on the enteric nervous system and diminishing nausea and vomiting in a variety of gastrointestinal conditions.

About Gastroparesis

Gastroparesis is a chronic gastric motility disorder characterized by delayed gastric emptying. Symptoms include early satiety, postprandial fullness, nausea, vomiting, and abdominal discomfort. The current approved drug available in the United States for treating these symptoms is metoclopramide, which carries a black box warning for tardive dyskinesia and is limited to acute use.

About Altos Therapeutics

Altos Therapeutics is a private pharmaceutical company located in Los Altos, California.  The company is committed to identifying and developing new medicines for gastrointestinal disorders in areas of high unmet medical need, including gastroparesis, functional dyspepsia, refractory gastroesophageal reflux disease (GERD), Parkinson's disease, and refractory nausea. 

Roger Whiting, Co-founder, President and CEO

Office: 650.948.1200
Fax: 650.948.1221



SOURCE Altos Therapeutics, LLC