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      Amyris, Inc. Reports Third Quarter 2021 Financial Results

      - Record underlying revenue and record consumer revenue

      - Launched four consumer brands. Bolstered strategic consumer capability from acquisitions

      - Supply chain challenges impacting near term performance. Growth trajectory intact

      Amyris Logo (PRNewsfoto/Amyris, Inc.)

      News provided by

      Amyris, Inc.

      Nov 08, 2021, 16:11 ET

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      EMERYVILLE, Calif., Nov. 8, 2021 /PRNewswire/ -- Amyris, Inc. (Nasdaq: AMRS), a leading synthetic biotechnology company accelerating the world to sustainable consumption through its Lab-to-MarketTM operating platform, today announced financial results for its third quarter ended September 30, 2021.

      "Amyris delivered another strong quarter along with solid strategic execution amid challenging external global supply chain conditions," said John Melo, President and Chief Executive Officer. "Once again, we realized record underlying revenue and record consumer revenue demonstrating continued year-over-year and sequential growth. We launched four new consumer brands in the quarter further expanding our foothold in clean beauty and personal care end-markets. Rose Inc.TM clean color cosmetics, JVNTM clean haircare and Terasana® clean skincare are each formulated with one, or a combination, of our unique sustainable ingredients that we created and manufacture leveraging the power of our Lab-to-MarketTM operating platform. Additionally, we launched OlikaTM. We completed three acquisitions including Olika, Beauty Labs and MG Empower adding strategic digital, online influencer and social selling capabilities as approximately 50% of our consumer revenue is being generated from e-commerce which is our fastest growing and best gross margin business channel."

      "Our science and partnerships continue to deliver new opportunities. We are very excited about our JV partnership with ImmunityBio for the commercialization of a second generation COVID-19 vaccine which expands our business into biopharma. We continued to progress the construction of our new Brazil ingredients plant with expected production in early 2022 as well as the establishing our consumer production facility in Reno, Nevada by the middle of next year."

      "Worldwide supply chain disruptions combined with late quarter launches of the new brands resulted in lower-than-expected revenue. Shipping delays impacted supply of raw materials and customer shipments while freight expense significantly increased. Although global in nature and persisting in the fourth quarter, we believe these are short-term issues and that they have no impact on our long-term growth targets. We continue to experience very robust demand that more than supports our outlook. Looking ahead to 2022, we are taking control of our supply chain with the investments in Brazil and Reno to reduce our third-party dependency and our exposure to shipping delays resulting in lower operating costs and expanded gross margins. We now expect full year 2021 total revenue to be in the $330 - $370 million range, doubling full year 2020. We have the inventory on hand to deliver within this range and subject to easing supply chain headwinds could attain upside."

      "We continue to strategically progress our capital structure to eliminate remaining legacy debt and bring in growth capital to support our ambitious operational and financial growth targets."

      Business and Operational Highlights

      • Record Q3 underlying revenue of $48 million increased 40% continuing the year-over-year and sequential growth trajectory. Record consumer revenue of $23 million increased 89% versus Q3 2020. The total number of consumer brands grew from 1 in 2018, and 3 in 2019, to 8 in Q3 2021. Year-to-date Q3 2021 consumer revenue of $60 million grew from $6 million for the same period in 2018, 10.7X or a 121% CAGR.
      • During September, Rose Inc. and JVN hosted a number of launch events in the U.S. and internationally, including social media campaigns to accelerate brand awareness and educate consumers on the power of Squalane, Hemi-Squalane and Biosilica as differentiated core ingredients to these brands. JVN was launched with 9 SKUs in 62 Sephora stores with stores expected to triple over the next quarter. Rose Inc. was launched with 16 SKUs in Sephora North America and Space NK in the U.K. Both brands are accelerating revenue into the fourth quarter and are expected to exceed $20 million revenue each in their first 12 months. This would be our strongest performance for new brands
      • Biossance®'s international expansion continued through Space NK in the U.K. and can now be found in 14 different retailer chains worldwide. Pipette continued to deliver on its commitment to improve the accessibility of clean products for babies, mothers and families. Pipette can now be found in 236 new stores across Canada and also launched in 118 new stores in the U.S. during Q3.
      • Amyris and ImmunityBio (Nasdaq: IBRX) announced a JV for the commercialization of a next-generation COVID-19 RNA vaccine. Upon completion of successful human trials, the joint-venture's goal is to deliver one billion doses of the new vaccine in 2022 addressing the unmet needs of access to vaccines in developing countries and other regions of the world, addressing cold-chain and durability challenges facing the world today.
      • Through the end of Q3 sales volumes for Squalane, used in skin care and other products, surpassed total 2020 sales volumes. Demand for Hemi-Squalane for haircare, is driven by increasing regulatory pressure to reduce the use of environmentally harmful silicones.
      • Q3 was critical for our consumer supply chain to support brand launches and to also prepare for the end-of-year holiday season. 90% of projected product demand is in our distribution centers available for sale. During Q3 we experienced supply chain challenges with significant port delays for critical raw materials due to labor shortages affecting the production of Squalane and Hemi-Squalane. These delays resulted in a 20% shortfall in our Squalane production target. We incurred additional cost from increased shipping expense and expedited air shipping. We anticipate shipping and port unloading issues to continue in Q4.
      • We continued to manage COVID-19 with a very successful management and monitoring program while having 250-300 construction workers at the Brazil ingredients plant construction site. Commodity cost increases affected the cost of construction materials such as steel. Commissioning of the plant remains on schedule for early 2022.
      • We expect to finalize negotiations for three new consumer brands over the next three months. These are strategic additions and represent significant opportunity for our ingredient portfolio.

      Q3 and YTD 2021 Sales Revenue


      Three Months Ended
      September 30,


      Nine Months Ended
      September 30,

      (In millions)

      2021

      2020

      YoY%


      2021

      2020

      YoY%

      Consumer

      $23.2

      $12.3

      89%


      $   59.6

      $34.4

      73%

      Ingredients

      13.3

      18.8

      -30%


      42.5

      42.2

      1%

      Product

      $36.5

      $31.1

      17%


      $102.1

      $76.6

      33%

      R&D and Other Services

      11.4

      3.1

      264%


      21.4

      12.0

      78%

      Underlying Total

      $47.9

      $34.3

      40%


      $123.4

      $88.6

      39%

      Other1

      0.0

      0.0

      -


      153.6

      4.8

      3090%

      Reported Total

      $47.9

      $34.3

      40%


      $277.0

      $93.4

      197%









      1 Other: $4.8m Vitamin E transaction (Q1 2020), $143.6m DSM F&F transaction (Q1 2021), $10.0m Ingredion Reb M transaction (Q2 2021).

      Q3 2021 Financial Highlights

      • Total revenue of $47.9 million, increased 40% compared to Q3 2020 revenue of $34.3 million. Product revenue of $36.5 million increased 17% compared to Q3 2020 product revenue of $31.1 million driven by record consumer revenue of $23.2 million, an 89% increase, which was partially offset by a decrease in ingredient sales.
      • Non-GAAP gross margin of $17.7 million, or 37% of revenue, grew from $14.2 million, or 41% of revenue in Q3 2020 primarily due to increased consumer revenue.
      • Cash operating expense of $81.4 million increased by $38.1 million, or 88%, compared to Q3 2020, primarily due to a $28.1 million increase in selling expense due to higher headcount, growth driven fulfillment and shipping expense and launches of new brands. R&D and G&A expense increased by $4.4 million and $5.6 million respectively due to higher headcount, M&A expense and comparatively low prior year travel expense due to COVID-19.
      • Adjusted EBITDA of -$73.1 million decreased $40 million year-over-year, primarily due to higher operating expense.
      • GAAP net income/loss is significantly influenced by non-cash mark-to-market adjustments related to changes in the fair value of debt and derivatives. GAAP net loss of $32.9 million or $0.11 per share compared to a loss of $83.5 million or $0.37 per share in Q3 2020. Adjusted net loss of $80.1 million, or $0.27 per share, compared to an adjusted net loss of $50.0 million, or $0.22 per share in Q3 2020.
      • Cash at the end of the quarter was $115 million, compared to $38 million at the end of Q3 2020.
      • Total debt principal at the end of the quarter was $102 million, compared to $175 million at the end of Q3 2020. Interest expense for Q3 2021 was $4 million compared to $7 million in Q3 2020 due to reduced debt.

      YTD 2021 Financial Highlights

      • Total YTD revenue of $277.0 million improved 197% versus the prior year period. Total revenue included $153.6 million of proceeds resulting from strategic transactions. Total underlying revenue (product and R&D and other services) increased 39% to $123.4 million compared to $88.6 million in first 9 months of 2020. Product revenue of $102.1 million increased $25.5 million, or 33%, compared to the first 9 months of 2020 driven by a $25.2 million, or 73%, increase in consumer sales.
      • Non-GAAP gross margin of $205.0 million, or 74% of revenue, grew from $43.5 million or 47% of revenue in first nine months of 2020. Excluding the contribution from the strategic transactions, gross margin of $51.4 million grew $12.8 million compared to first nine months of 2020 primarily due to consumer-related growth.
      • Cash operating expense of $198.0 million increased by $67.5 million, or 52%, compared to first 9 months of 2020 primarily due to investments in consumer brands, new consumer brand launches, increased headcount and additional R&D spend.
      • Adjusted EBITDA of -$12.2 million improved $84.4 million year-over-year due to revenue and margin growth and proceeds from strategic transactions.
      • GAAP net loss was $308.0 million or $1.07 per share compared to a loss of $273.2 million or $1.44 per share in the first 9 months of 2020. Adjusted net loss was $34.2 million, or $0.12 per share compared to adjusted net loss of $152.2 million, or $0.80 per share, for the first 9 months of 2020.

      Outlook – Update to Guidance Provided on August 5, 2021

      • Amyris now expects reported total revenue for the full year, inclusive of strategic transactions of $154 million, to be in a range of $330 - $370 million.

      Conference Call

      Amyris will host its third quarter 2021 conference call today at 4:30 pm ET (1:30 pm PT) to discuss its financial results and provide a business and financial update.

      Live audio webcast/conference call:

      Webcast: please visit http://investors.amyris.com.

      U.S. Dial-In Number: (844) 850-0551. International Dial-In Number: (412) 902-4203.

      Please connect to the website or dial in to the conference call 15 minutes prior to the start of the call to avoid connection delays. If a participant will be listen-only, they are encouraged to listen via the webcast on Amyris' investor page.

      A replay of the webcast will be available on the Investor Relations section of Amyris' website.

      FINANCIAL RESULTS AND NON-GAAP INFORMATION

      To supplement our financial results and guidance presented in accordance with U.S. generally accepted accounting principles (GAAP), we use certain non-GAAP financial measures that we believe are helpful in understanding our financial results. These non-GAAP financial measures are among the factors management uses in planning and forecasting future periods. These non-GAAP financial measures also facilitate management's internal comparisons to Amyris' historical performance as well as comparisons to the operating results of other companies. Management believes these non-GAAP financial measures, when considered together with financial information prepared in accordance with GAAP, can enhance investors' and analysts' abilities to meaningfully compare our results from period to period, identify operating trends in our business, and track and model our financial performance. In addition, our management believes that these non-GAAP financial measures allow for greater transparency into the indicators used by management to understand and evaluate our business and make operating decisions.

      Non-GAAP financial information is not prepared under a comprehensive set of accounting rules, and therefore, should only be read in conjunction with financial information reported under GAAP in order to understand Amyris' operating performance. A reconciliation of the non-GAAP financial measures presented in this release to the most directly comparable GAAP financial measure, is provided in the tables attached to this press release.

      Our Non-GAAP financial measures include the following:

      Non-GAAP Gross Margin (Gross Margin) is calculated as GAAP revenue less non-GAAP cost of products sold divided by GAAP revenue. Non-GAAP cost of products sold excludes other costs/provisions, inventory lower of cost or net realizable value adjustments, excess capacity, manufacturing capacity fee adjustments, stock-based compensation expense, depreciation and amortization.

      Non-GAAP Cash Operating Expense is calculated as GAAP Operating Expense minus non-cash stock-based compensation, depreciation and amortization, non-recurring transaction and acquisition expense, contract credit loss reserve, and R&D performance agreement termination.

      EBITDA is calculated as GAAP net income (loss) less interest, expense, income tax expense, depreciation and amortization expense, deemed dividends to preferred stockholders, and loss allocated to participating securities.

      Adjusted EBITDA is calculated as EBITDA less income attributable to noncontrolling interest, gain/loss from change in fair value of derivatives, gain/loss from changes in the fair value of debt, loss upon debt extinguishment, other income/expense, loss from investment in affiliate, inventory lower of cost or net realizable value adjustments, non-recurring transaction and acquisition expense, stock-based compensation expense, R&D performance agreement termination, manufacturing capacity fee adjustment and contract asset credit loss reserve.

      Adjusted net income (loss) is calculated as GAAP net income/loss excluding stock-based compensation expense, gain/loss from change in fair value of derivatives, gain/ loss from changes in the fair value of debt, losses upon debt extinguishment, income/loss attributable to noncontrolling interest, loss allocated to participating securities, inventory lower of cost or net realizable value adjustments, R&D performance agreement termination, manufacturing capacity fee adjustments, non-recurring transaction and acquisition expense, other income/expense, and gain/loss from investment in affiliate.

      Adjusted EPS is calculated by dividing adjusted net income (loss) by the weighted average shares, basic outstanding for the period.

      About Amyris
      Amyris (Nasdaq: AMRS) is a leading synthetic biotechnology company, transitioning the Clean Health & Beauty and Flavors & Fragrances markets to sustainable ingredients through fermentation and the company's proprietary Lab-to-MarketTM operating platform. This Amyris platform leverages state-of-the-art machine learning, robotics and artificial intelligence, enabling the company to rapidly bring new innovation to market at commercial scale. Amyris ingredients are included in over 20,000 products from the world's top brands, reaching more than 300 million consumers. Amyris also owns and operates a family of consumer brands that is constantly evolving to meet the growing demand for sustainable, effective and accessible products. For more information, please visit http://www.amyris.com.

      Amyris, the Amyris logo, No Compromise, Biossance, Pipette, Purecane, Terasana, Rose Inc. and Lab-to-Market are trademarks or registered trademarks of Amyris, Inc. in the U.S. and/or other countries.

      Forward-Looking Statements

      This release contains forward-looking statements, and any statements other than statements of historical fact could be deemed to be forward-looking statements. These forward-looking statements include, among other things, statements regarding future events, such as Amyris' financial outlook and goals for the remainder of 2021 and beyond; Amyris' expectations regarding supply chain issues in Q4 and beyond and the limited impact of such issues on long-term growth targets; Amyris' expectations about increasing consumer demand for sustainable products and the acceleration of revenue of newly launched brands; Amyris' expectations regarding its JV partnership with ImmunityBio and the development, manufacturing, and commercialization of its COVID-19 vaccine which expands its business into biopharma and the timing thereof; Amyris' expectation of adding three new consumer brands and the timing thereof; and Amyris' expectations regarding the commissioning of its Brazil manufacturing facility, the timing thereof and benefits thereof in alleviating cost pressures. These statements are based on management's current expectations and actual results and future events may differ materially due to risks and uncertainties, including risks related to Amyris' liquidity and ability to fund operating and capital expenses, risks related to its financing activities, risks related to potential delays or failures in completing and integrating planned acquisitions, risks related to potential delays or failures in development, regulatory approval, launch, production and commercialization of products, risks related to Amyris' reliance on third parties particularly in the supply chain, and other risks detailed from time to time in filings Amyris makes with the Securities and Exchange Commission, including Annual Reports on Form 10-K, Quarterly Reports on Form 10-Q and Current Reports on Form 8-K. Amyris disclaims any obligation to update information contained in these forward-looking statements, whether as a result of new information, future events, or otherwise.

      Financial Tables Follow

      Amyris, Inc. 



      CONDENSED CONSOLIDATED BALANCE SHEETS



      (In thousands

      September 30, 2021

      December 31, 2020

      Assets



      Current assets:



      Cash and cash equivalents

      $                  114,887

      $           30,152

      Restricted cash

      286

      309

      Accounts receivable, net

      34,920

      32,846

      Accounts receivable - related party, net

      10,841

      12,110

      Contract assets

      3,513

      4,178

      Contract assets - related party

      2,000

      1,203

      Inventories

      72,062

      42,862

      Deferred cost of products sold - related party

      9,182

      9,801

      Prepaid expenses and other current assets

      30,373

      13,103

      Total current assets

      278,064

      146,564

      Property, plant and equipment, net

      53,124

      32,875

      Deferred cost of products sold, noncurrent - related party

      3,061

      9,939

      Restricted cash, noncurrent

      961

      961

      Recoverable taxes from Brazilian government entities

      13,005

      8,641

      Right-of-use assets under financing leases, net

      7,996

      9,994

      Right-of-use assets under operating leases, net

      10,989

      10,136

      Goodwill

      128,692

      -

      Intangible assets, net

      39,662

      -

      Other assets

      6,753

      3,704

      Total assets

      $                  542,307

      $         222,814

      Liabilities, Mezzanine Equity and Stockholders' Deficit



      Current liabilities:



      Accounts payable

      $                    80,645

      $           41,045

      Accrued and other current liabilities

      62,681

      30,707

      Financing lease liabilities

      1,182

      4,170

      Operating lease liabilities

      6,786

      5,226

      Contract liabilities

      3,486

      4,468

      Debt, current portion

      24,614

      54,748

      Related party debt, current portion

      280,633

      22,689

      Total current liabilities

      460,027

      163,053

      Long-term debt, net of current portion

      12,099

      26,170

      Related party debt, net of current portion

      5,000

      159,452

      Financing lease liabilities, net of current portion

      63

      -

      Operating lease liabilities, net of current portion

      7,722

      9,732

      Derivative liabilities

      21,465

      8,698

      Acquisition-related contingent consideration

      65,077

      -

      Other noncurrent liabilities

      24,179

      22,754

      Total liabilities

      595,632

      389,859

      Commitments and contingencies



      Mezzanine equity:



      Contingently redeemable common stock

      5,000

      5,000

      Redeemable noncontrolling interest

      28,520

      -

      Stockholders' deficit:



      Preferred stock

      -

      -

      Common stock

      31

      24

      Additional paid-in capital

      2,358,441

      1,957,224

      Accumulated other comprehensive loss

      (52,134)

      (47,375)

      Accumulated deficit

      (2,395,506)

      (2,086,692)

      Total Amyris, Inc. stockholders' deficit

      (89,168)

      (176,819)

      Noncontrolling interest

      2,323

      4,774

      Total stockholders' deficit

      (86,845)

      (172,045)

      Total liabilities, mezzanine equity and stockholders' deficit

      $                  542,307

      $         222,814

      Amyris, Inc. 






      CONDENSED CONSOLIDATED STATEMENTS OF OPERATIONS
      (Unaudited)







      Three Months Ended September 30,


      Nine Months Ended September 30,

      (In thousands, except shares and per share amounts)

      2021

      2020


      2021

      2020

      Revenue:






      Renewable products

      $             36,508

      $             27,577


      $           101,859

      $             70,619

      Licenses and royalties

      6,006

      3,563


      160,806

      9,714

      Collaborations, grants and other

      5,352

      3,118


      14,376

      13,060

      Total revenue

      47,866

      34,258


      277,041

      93,393

      Cost and operating expenses:






      Cost of products sold(1)

      40,252

      25,822


      93,332

      60,710

      Research and development(1)

      23,824

      18,197


      69,580

      52,288

      Sales, general and administrative(1)

      70,635

      38,321


      162,897

      100,838

      Total cost and operating expenses

      134,711

      82,340


      325,809

      213,836

      Loss from operations

      (86,845)

      (48,082)


      (48,768)

      (120,443)

      Other income (expense):






      Interest expense

      (4,321)

      (6,627)


      (14,857)

      (41,747)

      Gain (loss) from change in fair value of derivative instruments

      4,778

      1,999


      (12,826)

      (6,498)

      Gain (loss) from change in fair value of debt

      52,294

      34,360


      (204,359)

      2,908

      Loss upon extinguishment of debt

      (680)

      (2,606)


      (27,058)

      (51,954)

      Other income (expense), net

      690

      (49)


      40

      1,452

      Total other income (expense), net

      52,761

      27,077


      (259,060)

      (95,839)

      Loss before income taxes and loss from investment in affiliate

      (34,084)

      (21,005)


      (307,828)

      (216,282)

      Provision for income taxes

      (58)

      (83)


      (170)

      (273)

      Gain (loss) from investment in affiliate

      181

      (366)


      (567)

      (1,058)

      Net loss

      (33,961)

      (21,454)


      (308,565)

      (217,613)

      Less: (income) loss attributable to noncontrolling interest

      1,017

      (1,702)


      (249)

      (3,809)

      Net loss attributable to Amyris, Inc.

      (32,944)

      (23,156)


      (308,814)

      (221,422)

      Less: deemed dividend to preferred stockholders upon conversion of Series E preferred stock

      -

      (67,151)


      -

      (67,151)

      Less: losses allocated to participating securities

      -

      6,832


      787

      15,369

      Net loss attributable to Amyris, Inc. common stockholders, basic

      $           (32,944)

      $           (83,475)


      $         (308,027)

      $         (273,204)







      Weighted-average shares of common stock outstanding used in computing loss per share of common stock, basic

      300,888,579

      227,267,553


      286,919,463

      189,192,973

      Loss per share attributable to common stockholders, basic

      $               (0.11)

      $               (0.37)


      $               (1.07)

      $               (1.44)







      Weighted-average shares of common stock outstanding used in computing loss per share of common stock, diluted

      317,568,913

      242,732,234


      286,919,463

      191,506,499

      Loss per share attributable to common stockholders, diluted

      $               (0.27)

      $               (0.41)


      $               (1.07)

      $               (1.46)







      (1)Includes stock-based compensation expense as follows:






      Cost of products sold

      $                    79

      $                    51


      $                  215

      $                    51

      Research and development 

      1,565

      928


      3,945

      2,774

      Sales, general and administrative

      7,261

      2,441


      17,772

      7,030


      $               8,905

      $               3,420


      $             21,932

      $               9,855

      Amyris, Inc. 






      RECONCILIATION OF GAAP TO NON-GAAP FINANCIAL INFORMATION
      (Unaudited)







      Three Months Ended September 30,


      Nine Months Ended September 30,

      (In thousands, except per share data)

      2021

      2020


      2021

      2020

      Net loss attributable to Amyris, Inc. common stockholders - Basic (GAAP)

      $           (32,944)

      $           (83,475)


      $         (308,027)

      $         (273,204)

      Non-GAAP adjustments:






      Non-recurring transaction and acquisition expense

      2,216

      -


      5,522

      -

      Stock-based compensation expense

      8,905

      3,420


      21,932

      9,855

      (Gain) loss from change in fair value of derivative instruments

      (4,778)

      (1,999)


      12,826

      6,498

      (Gain) loss from change in fair value of debt

      (52,294)

      (34,360)


      204,359

      (2,908)

      (Gain) loss upon extinguishment of debt

      680

      2,606


      27,058

      51,954

      Income (loss) attributable to noncontrolling interest

      (1,017)

      1,702


      249

      3,809

      Deemed dividend to preferred stockholders upon conversion of Series E preferred stock

      -

      67,151


      -

      67,151

      Loss allocated to participating securities

      -

      (6,832)


      (787)

      (15,369)

      Inventory lower-of-cost-or-net realizable value adjustment

      50

      1,337


      (1,183)

      374

      R&D Performance Agreement termination

      -

      -


      1,850

      -

      Manufacturing capacity fee adjustment

      -

      -


      1,482

      -

      Other (income) expense, net, and (gain) loss from investment in affiliate, net

      (871)

      415


      527

      (394)

      Net loss attributable to Amyris, Inc. common stockholders (non-GAAP)

      $           (80,053)

      $           (50,035)


      $           (34,192)

      $         (152,234)







      Weighted-average shares outstanding






      Weighted-average shares of common stock outstanding used in computing loss per share attributable to Amyris, Inc. common stockholders, diluted (GAAP and non-GAAP)

      317,568,913

      242,732,234


      286,919,463

      191,506,499







      Loss per share attributable to Amyris, Inc. common stockholders - Basic (GAAP)

      $               (0.11)

      $               (0.37)


      $               (1.07)

      $               (1.44)

      Non-GAAP adjustments:






      Non-recurring transaction and acquisition expense

      0.01

      -


      0.02

      -

      Stock-based compensation expense

      0.03

      0.02


      0.08

      0.05

      (Gain) loss from change in fair value of derivative instruments

      (0.02)

      (0.01)


      0.04

      0.03

      (Gain) loss from change in fair value of debt

      (0.17)

      (0.15)


      0.71

      (0.02)

      (Gain) loss upon extinguishment of debt

      0.00

      0.01


      0.09

      0.27

      Income (loss) attributable to noncontrolling interest

      (0.00)

      0.01


      0.00

      0.02

      Deemed dividend to preferred stockholders upon conversion of Series E preferred stock

      -

      0.30


      -

      0.35

      Loss allocated to participating securities

      -

      (0.03)


      (0.00)

      (0.08)

      Inventory lower-of-cost-or-net realizable value adjustment

      0.00

      0.01


      (0.00)

      0.00

      R&D Performance Agreement termination

      -

      -


      0.01

      -

      Manufacturing capacity fee adjustment

      -

      -


      0.01

      -

      Other (income) expense, net, and (gain) loss from investment in affiliate, net

      (0.00)

      0.00


      0.00

      (0.00)

      Loss per share attributable to Amyris, Inc. common stockholders (non-GAAP)(1)

      $               (0.27)

      $               (0.22)


      $               (0.12)

      $               (0.80)

      (1)Amounts may not sum due to rounding.







      Three Months Ended September 30,


      Nine Months Ended September 30,

      ADJUSTED EBITDA

      2021

      2020


      2021

      2020

      GAAP net loss attributable to Amyris, Inc. common stockholders - Basic

      $           (32,944)

      $           (83,475)


      $         (308,027)

      $         (273,204)

      Interest expense

      4,321

      6,627


      14,857

      41,747

      Income taxes

      58

      83


      170

      273

      Depreciation and amortization

      2,571

      1,905


      7,007

      5,300

      Loss allocated to participating securities

      -

      (6,832)


      (787)

      (15,369)

      Deemed dividend to preferred stockholders upon conversion of Series E preferred stock

      -

      67,151


      -

      67,151

      EBITDA

      (25,994)

      (14,541)


      (286,780)

      (174,102)

      Income (loss) attributable to noncontrolling interest

      (1,017)

      1,702


      249

      3,809

      (Gain) loss from change in fair value of derivative instruments and debt, (gain) loss upon extinguishment of debt, other (income) expense, and (gain) loss from investment in affiliate

      (57,263)

      (33,338)


      244,770

      55,150

      Inventory lower-of-cost-or-net realizable value adjustment

      50

      1,337


      (1,183)

      374

      R&D performance agreement termination

      -

      -


      1,850

      -

      Manufacturing capacity fee adjustment

      -

      -


      1,482

      -

      Stock-based compensation

      8,905

      3,420


      21,932

      9,855

      Contract asset credit loss reserve

      -

      8,342


      -

      8,399

      Non-recurring transaction and acquisition expense

      2,216

      -


      5,522

      -

      Adjusted EBITDA

      $           (73,103)

      $           (33,078)


      $           (12,158)

      $           (96,515)

      Amyris, Inc. 






      RECONCILIATION OF GAAP TO NON-GAAP
      FINANCIAL INFORMATION
      (Unaudited)







      Three Months Ended September 30,


      Nine Months Ended September 30,

      (In thousands)

      2021

      2020


      2021

      2020

      Revenue (GAAP and non-GAAP)






      Renewable products

      $ 36,508

      $       27,577


      $     101,859

      $       70,619

      Licenses and royalties

      6,006

      3,563


      160,806

      9,714

      Collaborations, grants and other

      5,352

      3,118


      14,376

      13,060

      Revenue (GAAP and non-GAAP)

      $ 47,866

      $       34,258


      $     277,041

      $       93,393







      Cost of products sold (GAAP)

      $ 40,252

      $       25,822


      $       93,332

      $       60,710

      Other costs/provisions

      (8,690)

      (3,848)


      (17,372)

      (8,937)

      Manufacturing capacity fee adjustment

      -

      -


      (1,482)

      -

      Inventory lower-of-cost-or-net realizable value adjustment

      (50)

      (1,337)


      1,183

      (374)

      Excess capacity

      (762)

      (90)


      (1,799)

      (571)

      Stock-based compensation expense

      (79)

      (51)


      (215)

      (51)

      Depreciation and amortization

      (554)

      (407)


      (1,618)

      (846)

      Cost of products sold (non-GAAP)

      $ 30,117

      $       20,089


      $       72,029

      $       49,931







      Adjusted gross profit (non-GAAP)

      $ 17,749

      $       14,169


      $     205,012

      $       43,462

      Gross margin %

      37%

      41%


      74%

      47%







      Research and development expense (GAAP)

      $ 23,824

      $       18,197


      $       69,580

      $       52,288

      Stock-based compensation expense

      (1,565)

      (928)


      (3,945)

      (2,774)

      Depreciation and amortization

      (1,366)

      (1,271)


      (4,037)

      (3,763)

      R&D performance agreement termination

      -

      -


      (1,850)

      -

      Research and development expense (non-GAAP)

      $ 20,893

      $       15,998


      $       59,748

      $       45,751







      Sales, general and administrative expense (GAAP)

      $ 70,635

      $       38,321


      $     162,897

      $     100,838

      Stock-based compensation expense

      (7,261)

      (2,441)


      (17,772)

      (7,030)

      Depreciation and amortization

      (651)

      (227)


      (1,352)

      (691)

      Contract asset credit loss reserve

      -

      (8,342)


      -

      (8,399)

      Non-recurring transaction and acquisition expense

      (2,216)

      -


      (5,522)

      -

      Sales, general and administrative expense (non-GAAP)

      $ 60,507

      $       27,311


      $     138,251

      $       84,718







      Cash operating expense

      $ 81,400

      $       43,309


      $     197,999

      $     130,469

      SOURCE Amyris, Inc.

      Modal title

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