Biopredic International and Triangle Research Labs Announce the Distribution of No-Spin Cryopreserved HepaRG™ cells by TRL in the United States

RESEARCH TRIANGLE PARK, N.C., Aug. 6, 2014 /PRNewswire/ -- Triangle Research Labs, LLC and Biopredic International have completed an agreement for TRL to distribute the No-Spin HepaRG™ cells in North America.  The No-Spin HepaRG™ represent an important improvement over the original cryopreserved HepaRG™ cells introduced three years ago for ADMET analyses. The HepaRG™ are renewable and reproducible hepatic cells derived from a single donor which possess the unique capabilities of being grown to increase their population, but can also be differentiated into fully-functional, adult phenotype hepatic cells. The cells have been the subject of dozens of recent scientific papers and posters, demonstrating their suitability for all in-vitro analyses for which the more variable and expensive cryopreserved primary human hepatocytes have been used.

The No-Spin HepaRG™ utilize a proprietary cryopreservation process developed by Biopredic that leverages the consistency and predictability of HepaRG responses and their post-thaw viability (typically 93-98%) with novel techniques developed by Biopredic scientists. All other forms of cryopreserved hepatocytes require thawing, suspension, centrifugation, resuspension, and counting (to account for variability introduced) steps; the No-Spin HepaRG™ simply need to be thawed and then they are ready for use. Not only will this benefit high-volume labs which now undertake many laborious and expensive steps to use hepatocytes, but all labs will gain from this format which reduces the risk of errors or variability.

"Biopredic is excited to have TRL as our North American partner for our improved, no-spin version of our key product, HepaRG™," said Christophe Chesne, CEO of Biopredic International.  "TRL has a deep understanding and commitment to the hepatocyte and ADMET market and will position the HepaRG with their own hepatocytes to provide the best models to benefit the customers. TRL will not only promote the use of the cells to industry and academic scientists but also open new applications based on recent impressive published findings demonstrating increasingly broad applications for the cells, often in applications where typical human hepatocytes are too variable, short-lived, or fragile to be relied upon. I am confident the relationship will benefit both companies and the industry overall," said Christophe.

"TRL is thrilled to now offer the NoSpin HepaRG™ cells and related media.  These cells are a complement to our current primary hepatocyte products and function across numerous applications in ADMETox and beyond," said Matt Sherman, Executive Director of Triangle Research Labs, LLC.  "Biopredic's expertise in producing the HepaRG will ensure that we are consistent in providing the highest quality products to our customers."

About Biopredic International
Since 1993, Biopredic International produces and distributes human and animal products (tissues, primary cells, cell lines, blood products, fluids) for academic and private research in drug discovery, drug development and cosmetics. With 50% of the sales made overseas, Biopredic International is recognized worldwide for its expertise in liver products (tissues, primary cells) and is the exclusive worldwide licensor of the HepaRG cell line.

About Triangle Research Labs, LLC
TRL is one of the fastest growing biotechnology companies in the United States.  TRL produces high quality hepatocytes for use in pre-clinical in vitro ADMETox applications. TRL provides both human and animal, fresh and cryopreserved hepatocytes, and their relevant media.  With decades of experience in the hepatic sciences, TRL is a known leader in quality, service, and value in the business.  For additional information, please refer to the company's website at www.triangleresearchlabs.com or call 1-919-549-3593.

Media contact
For more information, contact Biopredic International via [email protected] or +33 2 14 36 35 14.  Or contact Triangle Research Labs via [email protected] or 1-919-549-3593.

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SOURCE Triangle Research Labs