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DDW Presentation Examines Stretta As A Versatile And Effective GERD Treatment For Multiple Patient Populations
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News provided by

Mederi Therapeutics Inc.

May 27, 2015, 07:11 ET

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WASHINGTON, May 27, 2015 /PRNewswire/ -- A special presentation at Digestive Disease Week 2015 featured GERD experts weighing in on their successful experience using Stretta Therapy to treat challenging patient populations suffering from GERD.

Ronnie Fass, MD, of Case Western Reserve University moderated the discussion, and reviewed clinical data on Stretta. Expert panelists then addressed specific types of chronic GERD patients that Stretta has helped them treat.

Continue Reading
Stretta is a versatile treatment that satisfies an unmet need in multiple patient populations with chronic GERD. Stretta therapy is a non-surgical treatment for GERD that uses non-ablative radiofrequency (NARF) energy to improve the structure of the muscle at the junction of the stomach and esophagus, thereby significantly improving GERD symptoms. Stretta fills the treatment gap when PPIs are ineffective and before anti-reflux surgery, and does not preclude future surgery if necessary. Additionally...
Stretta is a versatile treatment that satisfies an unmet need in multiple patient populations with chronic GERD. Stretta therapy is a non-surgical treatment for GERD that uses non-ablative radiofrequency (NARF) energy to improve the structure of the muscle at the junction of the stomach and esophagus, thereby significantly improving GERD symptoms. Stretta fills the treatment gap when PPIs are ineffective and before anti-reflux surgery, and does not preclude future surgery if necessary. Additionally...

     Dana Portenier, MD, Duke University School of Medicine
     Stretta in GERD After Bariatric Surgery

     Hiroshi Mashimo, MD, PhD, VA Boston Healthcare/Harvard Medical School 
     Stretta in LPR Patients

     George Triadafilopoulos, MD, Stanford University School of Medicine
     Stretta in Refractory GERD

     Mark Noar, MD, Heartburn and Reflux Study Center
     Stretta in GERD After Anti-Reflux Surgery

Dr. Portenier highlighted the challenge of treating bariatric patients with GERD, noting that Duke has introduced Stretta to treat obese patients with chronic GERD, especially those after Sleeve Gastrectomy. "This is an area where Stretta makes a lot of sense. These patients are generally unwilling to have their sleeve converted to a Gastric Bypass just to fix their GERD," Portenier said. "With Stretta they avoid additional surgery. In the outstanding results we are seeing at Duke, most Stretta patients see complete or partial resolution of symptoms and are able to get off PPIs." "Stretta is a very low risk endoscopic procedure for these patients," he added.

Discussing refractory GERD sufferers, Dr. Triadafilopoulos explained that these patients experience reflux despite PPI therapy. According to Dr. Triadafilopoulos, there is a large gap between those who don't adequately respond to PPIs and those who choose anti-reflux surgery. "Stretta spans this gap with an outpatient, endoscopic option that has been proven effective and safe for up to 10 years." He presented the case of a refractory GERD patient who underwent Stretta. "The patient experienced heartburn, chest pain and regurgitation despite diet changes and PPI therapy. Testing showed abnormal esophageal acid exposure despite twice daily PPI. Six-months after Stretta, the patient is asymptomatic except for occasional gastric discomfort after meals, is off PPIs, uses occasional antacids, and has a normal pH study."

Dr. Mashimo reviewed his experience with Stretta in laryngopharyngeal reflux (LPR), a condition with symptoms such as chronic cough, hoarseness, asthma and chest pain, often presenting without heartburn. Also called atypical or silent reflux, LPR is caused by a backflow of gastric contents into the pharynx. "Often, LPR patients don't respond well to PPIs and only about half improve after anti-reflux surgery." Mashimo elaborated with a patient example. "The patient had globus sensation and chronic cough, with non-seasonal asthma not responsive to medications. One month after Stretta, she experienced a marked improvement, and one year later the grateful patient had nearly complete resolution of symptoms, and was off PPIs."

Dr. Noar discussed the Stretta option for GERD after anti-reflux surgery (Nissen fundoplication), explaining that 10 years after a Nissen, studies show recurring GERD in up to 42 percent of patients. Reviewing failed Nissen patients from the Stretta 10-year study he noted, "A decade later, 64 percent of these patients were still off daily PPIs." He added, "Stretta treats the internal lower esophageal sphincter without altering the anatomy, important for those with prior surgery, and the only non-surgical option for this type of patient."

"These topics represent unmet needs in GERD treatment where Stretta may be an option to effectively treat chronic sufferers," Dr. Fass added.

For more information, go to www.stretta-therapy.com.

ABOUT MEDERI® -
Mederi manufactures Stretta and Secca – innovative medical devices that deliver non-ablative RF energy for safe and effective treatment of digestive diseases.

Contact: Julia Brannan
[email protected]
(908) 464-2470

Infographic - http://photos.prnewswire.com/prnh/20150527/218687-INFO

SOURCE Mederi Therapeutics Inc.

Related Links

http://www.stretta-therapy.com

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