SANTA MONICA, Calif., Oct. 13, 2016 /PRNewswire/ -- Doctor Evidence (DRE) announces the launch of GROWTH Research, a new initiative to connect patient-level data to peer-reviewed data for clinical and policy decisions applicable at institutional, national, or global levels. GROWTH Research enables organizations to use the syntheses and analytic results of publicly validated data from the peer-reviewed literature to mine and investigate patient-level data for research and discovery purposes. 

"The peer reviewed literature is often criticized for not being representative of the 'real-world,'" said Bob Battista, CEO of Doctor Evidence. "Peer review systems provide a critical role in validating data and creating baseline efficacy and safety profiles.  We can then use these baselines for mining and investigating data from the vast universe of observed events in various real-world settings, be they electronic medical records, claims databases, patient surveys, and other sources of patient-level observational data."

GROWTH Research creates a new standard of a networked community for collaborations to use medical evidence in clinical research programs by medical specialty societies, governments, R&D organizations, hospital systems, payers, and universities. This new program expands on GROWTH, a Doctor Evidence initiative to promote high quality data and resource sharing among evidence-based medicine (EBM) organizations globally with the ultimate goal of improving patient outcomes.

Demetrius Maraganore, M.D., Chair, Department of Neurology, NorthShore University HealthSystem, stated: "GROWTH Research provides clinician investigators with the knowledge to make evidence-based designs of clinical trials using published data. I envision designing pragmatic trials (e.g., using the EMR and subgroup-based adaptive designs to compare treatments for neurological disorders), informed by GROWTH meta-analyses of existing trials, guiding the selection of subjects, outcome measures, and independent variables."

GROWTH Research participants receive unlimited access to data from pre-digitized studies within the Doctor Evidence database, now comprising over 20,000 studies and growing daily. This enhances resource sharing, reduces duplication of efforts, and lowers overall costs. EBM organizations and research centers are no longer burdened with the tediousness of isolated and de novo data extractions. With these state-of-the-art and dynamically-updatable digital resources, researchers can query the data more deeply and perceptively to answer higher level clinical questions. Incorporating economic data permits decision-makers to allocate resources equitably.

Chris Murray, M.D., Professor of Global Health at the University of Washington and Director of the Institute for Health Metrics and Evaluation, proclaimed: "Doctor Evidence has built incredible tools and a fantastic approach to extracting, storing, exploring, and meta-analyzing the published literature. This work of synthesizing the peer-reviewed data is important to identify the best treatment options for various subgroups at varying levels of disease risk and burden."

About GROWTH

The Guideline & Research Organizations Worldwide for Transparency & Harmonization (GROWTH) initiative is committed to improving the health and quality of life of patients by encouraging the development of evidence-based clinical recommendations through collaboration and resource-sharing across the spectrum of evidence-based medicine. GROWTH utilizes Doctor Evidence's cutting-edge platform technologies and services to synthesize high quality data from a broad variety of sources including databases of published clinical studies (e.g., PubMed or EMBASE), clinical trials.gov data, clinical practice guidelines, health technology assessments, systematic reviews, regulatory filings and epidemiological data (e.g., NHANES, the National Health and Nutrition Examination Survey data from the Centers for Disease Control and Prevention). The resulting knowledge sets are leveraged, utilizing rigorous and transparent methodologies employing sophisticated analytic capabilities, to perform direct meta-analyses, network meta-analyses, meta-regressions, cohort analyses, and sensitivity analyses. These reliable results then support transparent and trusted reviews informing clinical trial designs, guidelines and protocols for patient care, healthcare policy decisions, and on-going research to identify the most efficacious and safe interventions for specific patients and populations. For more information, please visit http://growthevidence.com/.

About Doctor Evidence

Doctor Evidence, LLC, founded in 2004, is a leader in technological solutions for evidence-based systematic reviews and analyses with a mission to provide stakeholders across the healthcare ecosystem with the most relevant and timely medical evidence and related analytics to make and inform the best clinical decisions. Doctor Evidence is best known for its proprietary Digital Outcome Conversion (DOC) platform and its rigorous methodology of extracting clinical data from static, unstructured sources, including published studies, epidemiological databases, drug label and creating dynamically updatable, scientifically-curated data hubs. The digitized data can be pooled and analyzed to support the development of evidence-based clinical practice guideline recommendations, systematic reviews, and health technology assessments, and regulatory and policy submissions. The company's goal is to support the efforts of healthcare providers, healthcare professionals, and patients to gain access to important evidence-based knowledge and to improve the health and wellbeing of patients worldwide. Doctor Evidence is a global company headquartered in Santa Monica, California. For more information, please visit http://drevidence.com/.

About The Institute for Health Metrics and Evaluation (IHME) 

The Institute for Health Metrics and Evaluation (IHME) is an independent global health research organization at the University of Washington that provides rigorous and comparable measurement of the world's most important health problems and evaluates the strategies used to address them. IHME makes this information widely available so that policymakers have the evidence they need to make informed decisions about how to allocate resources to best improve population health. IHME has been funded by the Bill and Melinda Gate's Foundation.  The Institute is led by Christopher Murray, who is the subject of Jeremy Smith's book, Epic Measures. For more information, please visit http://www.healthdata.org/.

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