• Resources
  • Blog
  • Journalists
  • Log In
  • Sign Up
  • Data Privacy
  • Send a Release
Cision PR Newswire: news distribution, targeting and monitoring
  • News
  • Products
    • Overview
    • Distribution by PR Newswire
    • Cision Communications Cloud®
    • Cision IR
    • All Products
  • Contact
    • General Inquiries
    • Request a Demo
    • Editorial Bureaus
    • Partnerships
    • Media Inquiries
    • Worldwide Offices

Searching for your content...

No results found. Please change your search terms and try again.
  • News in Focus
      • Browse News Releases
      • All News Releases
      • All Public Company
      • English-only


      • News Releases Overview
      • Multimedia Gallery
      • All Multimedia
      • All Photos
      • All Videos


      • Multimedia Gallery Overview
      • Trending Topics
      • All Trending Topics


  • Business & Money
      • Auto & Transportation
      • All Automotive & Transportation
      • Aerospace, Defense
      • Air Freight
      • Airlines & Aviation
      • Automotive
      • Maritime & Shipbuilding
      • Railroads and Intermodal Transportation
      • Supply Chain/Logistics
      • Transportation, Trucking & Railroad
      • Travel
      • Trucking and Road Transportation


      • Auto & Transportation Overview
      • Business Technology
      • All Business Technology
      • Blockchain
      • Broadcast Tech
      • Computer & Electronics
      • Computer Hardware
      • Computer Software
      • Data Analytics
      • Electronic Commerce
      • Electronic Components
      • Electronic Design Automation
      • Financial Technology
      • High Tech Security
      • Internet Technology
      • Nanotechnology
      • Networks
      • Peripherals
      • Semiconductors


      • Business Technology Overview
      • Entertain­ment & Media
      • All Entertain­ment & Media
      • Advertising
      • Art
      • Books
      • Entertainment
      • Film and Motion Picture
      • Magazines
      • Music
      • Publishing & Information Services
      • Radio & Podcast
      • Television


      • Entertain­ment & Media Overview
      • Financial Services & Investing
      • All Financial Services & Investing
      • Accounting News & Issues
      • Acquisitions, Mergers and Takeovers
      • Banking & Financial Services
      • Bankruptcy
      • Bond & Stock Ratings
      • Conference Call Announcements
      • Contracts
      • Cryptocurrency
      • Dividends
      • Earnings
      • Earnings Forecasts & Projections
      • Financing Agreements
      • Insurance
      • Investments Opinions
      • Joint Ventures
      • Mutual Funds
      • Private Placement
      • Real Estate
      • Restructuring & Recapitalization
      • Sales Reports
      • Shareholder Activism
      • Stock Offering
      • Stock Split
      • Venture Capital


      • Financial Services & Investing Overview
      • General Business
      • All General Business
      • Awards
      • Commercial Real Estate
      • Corporate Expansion
      • Earnings
      • Human Resource & Workforce Management
      • Licensing
      • New Products & Services
      • Obituaries
      • Outsourcing Businesses
      • Overseas Real Estate (non-US)
      • Personnel Announcements
      • Real Estate Transactions
      • Residential Real Estate
      • Small Business Services
      • Socially Responsible Investing
      • Surveys, Polls and Research
      • Trade Show News


      • General Business Overview
  • Science & Tech
      • Consumer Technology
      • All Consumer Technology
      • Artificial Intelligence
      • Blockchain
      • Cloud Computing/Internet of Things
      • Computer Electronics
      • Computer Hardware
      • Computer Software
      • Consumer Electronics
      • Cryptocurrency
      • Data Analytics
      • Electronic Commerce
      • Electronic Gaming
      • Financial Technology
      • Mobile Entertainment
      • Multimedia & Internet
      • Peripherals
      • Social Media
      • STEM (Science, Tech, Engineering, Math)
      • Supply Chain/Logistics
      • Wireless Communications


      • Consumer Technology Overview
      • Energy & Natural Resources
      • All Energy
      • Alternative Energies
      • Chemical
      • Electrical Utilities
      • Gas
      • General Manufacturing
      • Mining
      • Mining & Metals
      • Oil & Energy
      • Oil and Gas Discoveries
      • Utilities
      • Water Utilities


      • Energy & Natural Resources Overview
      • Environ­ment
      • All Environ­ment
      • Conservation & Recycling
      • Environmental Issues
      • Environmental Policy
      • Environmental Products & Services
      • Green Technology
      • Natural Disasters


      • Environ­ment Overview
      • Heavy Industry & Manufacturing
      • All Heavy Industry & Manufacturing
      • Aerospace & Defense
      • Agriculture
      • Chemical
      • Construction & Building
      • General Manufacturing
      • HVAC (Heating, Ventilation and Air-Conditioning)
      • Machinery
      • Machine Tools, Metalworking and Metallurgy
      • Mining
      • Mining & Metals
      • Paper, Forest Products & Containers
      • Precious Metals
      • Textiles
      • Tobacco


      • Heavy Industry & Manufacturing Overview
      • Telecomm­unications
      • All Telecomm­unications
      • Carriers and Services
      • Mobile Entertainment
      • Networks
      • Peripherals
      • Telecommunications Equipment
      • Telecommunications Industry
      • VoIP (Voice over Internet Protocol)
      • Wireless Communications


      • Telecomm­unications Overview
  • Lifestyle & Health
      • Consumer Products & Retail
      • All Consumer Products & Retail
      • Animals & Pets
      • Beers, Wines and Spirits
      • Beverages
      • Bridal Services
      • Cannabis
      • Cosmetics and Personal Care
      • Fashion
      • Food & Beverages
      • Furniture and Furnishings
      • Home Improvement
      • Household, Consumer & Cosmetics
      • Household Products
      • Jewelry
      • Non-Alcoholic Beverages
      • Office Products
      • Organic Food
      • Product Recalls
      • Restaurants
      • Retail
      • Supermarkets
      • Toys


      • Consumer Products & Retail Overview
      • Entertain­ment & Media
      • All Entertain­ment & Media
      • Advertising
      • Art
      • Books
      • Entertainment
      • Film and Motion Picture
      • Magazines
      • Music
      • Publishing & Information Services
      • Radio & Podcast
      • Television


      • Entertain­ment & Media Overview
      • Health
      • All Health
      • Biometrics
      • Biotechnology
      • Clinical Trials & Medical Discoveries
      • Dentistry
      • FDA Approval
      • Fitness/Wellness
      • Health Care & Hospitals
      • Health Insurance
      • Infection Control
      • International Medical Approval
      • Medical Equipment
      • Medical Pharmaceuticals
      • Mental Health
      • Pharmaceuticals
      • Supplementary Medicine


      • Health Overview
      • Sports
      • All Sports
      • General Sports
      • Outdoors, Camping & Hiking
      • Sporting Events
      • Sports Equipment & Accessories


      • Sports Overview
      • Travel
      • All Travel
      • Amusement Parks and Tourist Attractions
      • Gambling & Casinos
      • Hotels and Resorts
      • Leisure & Tourism
      • Outdoors, Camping & Hiking
      • Passenger Aviation
      • Travel Industry


      • Travel Overview
  • Policy & Public Interest
      • Policy & Public Interest
      • All Policy & Public Interest
      • Advocacy Group Opinion
      • Animal Welfare
      • Congressional & Presidential Campaigns
      • Corporate Social Responsibility
      • Domestic Policy
      • Economic News, Trends, Analysis
      • Education
      • Environmental
      • European Government
      • FDA Approval
      • Federal and State Legislation
      • Federal Executive Branch & Agency
      • Foreign Policy & International Affairs
      • Homeland Security
      • Labor & Union
      • Legal Issues
      • Natural Disasters
      • Not For Profit
      • Patent Law
      • Public Safety
      • Trade Policy
      • U.S. State Policy


      • Policy & Public Interest Overview
  • People & Culture
      • People & Culture
      • All People & Culture
      • Aboriginal, First Nations & Native American
      • African American
      • Asian American
      • Children
      • Hispanic
      • Lesbian, Gay & Bisexual
      • Men's Interest
      • People with Disabilities
      • Religion
      • Senior Citizens
      • Veterans
      • Women


      • People & Culture Overview
      • In-Language News

      • español
      • português
      • Česko
      • Danmark
      • Deutschland
      • España
      • France
      • Italia
      • Nederland
      • Norge
      • Polska
      • Portugal
      • Россия
      • Slovensko
      • Suomi
      • Sverige
  • Overview
  • Distribution by PR Newswire
  • Cision Communications Cloud®
  • Cision IR
  • All Products
  • General Inquiries
  • Request a Demo
  • Editorial Bureaus
  • Partnerships
  • Media Inquiries
  • Worldwide Offices
  • PR Newswire: news distribution, targeting and monitoring
  • Send a Release
    • ALL CONTACT INFO

      Contact Us

      888-776-0942
      from 8 AM - 10 PM ET

  • Send a Release
  • Sign Up
  • Log In
  • Resources
  • Blog
  • Journalists
  • RSS
  • GDPR
  • News in Focus
    • Browse All News
    • Multimedia Gallery
    • Trending Topics
    • Send a Release
    • Sign Up
    • Log In
    • Resources
    • Blog
    • Journalists
    • RSS
    • GDPR
  • Business & Money
    • Auto & Transportation
    • Business Technology
    • Entertain­ment & Media
    • Financial Services & Investing
    • General Business
    • Send a Release
    • Sign Up
    • Log In
    • Resources
    • Blog
    • Journalists
    • RSS
    • GDPR
  • Science & Tech
    • Consumer Technology
    • Energy & Natural Resources
    • Environ­ment
    • Heavy Industry & Manufacturing
    • Telecomm­unications
    • Send a Release
    • Sign Up
    • Log In
    • Resources
    • Blog
    • Journalists
    • RSS
    • GDPR
  • Lifestyle & Health
    • Consumer Products & Retail
    • Entertain­ment & Media
    • Health
    • Sports
    • Travel
    • Send a Release
    • Sign Up
    • Log In
    • Resources
    • Blog
    • Journalists
    • RSS
    • GDPR
  • Policy & Public Interest
    • Send a Release
    • Sign Up
    • Log In
    • Resources
    • Blog
    • Journalists
    • RSS
    • GDPR
  • People & Culture
    • People & Culture
    • Send a Release
    • Sign Up
    • Log In
    • Resources
    • Blog
    • Journalists
    • RSS
    • GDPR
  • Send a Release
  • Sign Up
  • Log In
  • Resources
  • Blog
  • Journalists
  • RSS
  • GDPR
  • Overview
  • Distribution by PR Newswire
  • Cision Communications Cloud®
  • Cision IR
  • All Products
  • Send a Release
  • Sign Up
  • Log In
  • Resources
  • Blog
  • Journalists
  • RSS
  • GDPR
  • General Inquiries
  • Request a Demo
  • Editorial Bureaus
  • Partnerships
  • Media Inquiries
  • Worldwide Offices
  • Send a Release
  • Sign Up
  • Log In
  • Resources
  • Blog
  • Journalists
  • RSS
  • GDPR

Flagship Pioneering Unveils Pioneering Medicines

(PRNewsfoto/Flagship Pioneering)

News provided by

Flagship Pioneering

Jan 12, 2021, 10:00 ET

Share this article


CAMBRIDGE, Mass., Jan. 12, 2021 /PRNewswire/ -- Flagship Pioneering, a life science platforms company, today unveiled Pioneering Medicines, a new division of Flagship Pioneering. Initiated in 2020, Pioneering Medicines' mandate is to build a world-class biopharmaceutical R&D capability to conceive and develop a broad portfolio of life-changing treatments for patients.  By harnessing the power of Flagship's multiple scientific platforms, Pioneering Medicines will create and advance novel medicines that deliver benefits to more patients, sooner.

Delivering Benefits to More Patients, Sooner

Across the Flagship ecosystem, more than 40 companies are creating and applying innovative approaches to help address major health and sustainability issues.  Many of these Flagship platforms including RNA-based approaches such as Moderna and Omega Therapeutics , gene-based therapeutic approaches such as Sana Biotechnology, Tessera Therapeutics and Ring Therapeutics, cell therapy approaches such as Rubius Therapeutics and Sigilon Therapeutics, machine learning approaches such as Valo, Generate Biomedicines and Cellarity, and microbiome-related approaches such as Seres Therapeutics, Kaleido Biosciences and Evelo Biosciences, have broad applicability.  There is a tremendous opportunity to expand the impact of these platforms earlier by creating medicines in disease areas beyond where the individual companies are focused.   With visibility and access to all Flagship companies, Pioneering Medicines is well positioned to originate new medicine ideas based on these platforms. Pioneering Medicines also has the unique ability to combine these platforms, harnessing the power of multiple Flagship scientific innovations to create truly novel products.

"With a resolute focus on creating new products for patients, Pioneering Medicines will lead Flagship from making platforms innovations to advancing both platforms and products. It's an exciting opportunity with infinite possibilities to address a broad range of diseases," says Paul Biondi, Executive Partner and President of Pioneering Medicines within Flagship.

By identifying and pursuing new medicine opportunities in parallel as Flagship platform companies build out their platforms, Pioneering Medicines will be able to reach patients across more disease areas much sooner. 

Building a Portfolio Through Internal Exploration and Strategic Partnerships

Pioneering Medicines is leveraging Flagship's trademark innovation process to conceive novel ideas for new medicines.   Working closely with a Flagship platform company, Pioneering Medicines creates the product concept and leads the discovery and early-development efforts, advancing the asset through human proof-of-concept.  At that point, Pioneering Medicines will seek the most appropriate partner company to conduct late-stage development and commercialization. 

"Across the Flagship ecosystem, we have hundreds of scientists and thousands of colleagues pursuing ground-breaking advances built on novel scientific platforms every day.  Yet there are innumerable therapeutic opportunities that go unexplored.  Pioneering Medicines will leverage our unique innovation approach to uncover these opportunities, conceive new product concepts, and lead robust R&D programs in parallel to the strategies the platform companies are pursuing," says Noubar Afeyan, Ph.D., Founder and Chief Executive Officer of Flagship Pioneering.  "This unique model allows Flagship to achieve greater value from our existing scientific innovations for both patients and investors."

A complementary path to generating new product concepts is to collaborate with industry partners. Pioneering Medicines works with strategic partners to jointly conceive product concepts by combining partners' research priorities with Flagship's unique platform capabilities.  Partners gain access to the full spectrum of innovation across Flagship as well as the drug development expertise that Pioneering Medicines offers.

"We engage with companies to understand their therapeutic goals as well as scientific hurdles they have encountered.   Pioneering Medicines explores how the unique Flagship platforms, and the combination of platforms, can apply to this therapeutic intent and overcome the existing challenges," says Mr. Biondi. "Together we can conceive and explore entirely new approaches to treatment."

Pioneering Medicines' Leadership Team

Pioneering Medicines is establishing a world-class R&D capability with industry-leading R&D expertise that will advance medicines with speed and steadfast scientific rigor while also providing drug development expertise across the Flagship ecosystem.

  • Paul Biondi, Executive Partner and President of Pioneering Medicines, joined Flagship in November 2019 and spent the last year building the Pioneering Medicines strategy and capability, working across Flagship to conceive initial product concepts. Prior to Flagship, Paul spent 17 years at Bristol Myers Squibb (BMS) where he most recently had enterprise-wide responsibility for establishing and evolving BMS's strategy and for executing its business development efforts. Earlier in his BMS tenure, Paul spent 12 years in leadership roles within the R&D organization overseeing strategy, portfolio and project management and clinical business operations.
  • Luciano Rossetti, MD, Chief Medical Officer for Flagship and Head of R&D for Pioneering Medicines, joined Flagship earlier this month. Dr. Rossetti will be deeply engaged in the science and capabilities of the platforms within Flagship and will help shape the company's overall clinical portfolio. He will help lead Pioneering Medicines to conceive and build a portfolio of unique medicines sourced from the broad spectrum of Flagship's scientific platforms. Dr. Rossetti comes to Flagship after completing a six-year tenure as Global Head of Research & Development at Merck KGaA. He previously served as Merck & Co. Senior Vice President late-stage clinical development and before that was Head of Global Scientific Strategy across all therapeutic areas. Prior to joining the pharmaceutical industry, Dr. Rossetti spent 18 years in academic medicine.
  • Alec Reynolds, Senior Vice President, Head of Portfolio Strategy & Operations for Pioneering Medicines, joined Pioneering Medicines in May 2020 and is responsible for building Pioneering Medicines' operations model and a world-class portfolio strategy. Alec is a successful biotechnology leader who spent 12 years at Celgene and most recently led the project leadership function for all late-stage development projects in hematology-oncology and inflammation-immunology.
  • Pam Stetkiewicz, Senior Vice President, Global Program Leadership for Pioneering Medicines, joined Flagship in April 2020 to lead the advancement of Pioneering Medicines' portfolio in collaboration with Flagship platform companies and potential industry partners. Pam brings more than 20 years of extensive life-sciences pharmaceutical experience with recent experience at Editas Medicine and, prior to that, Novartis Institute of Biomedical Research.
  • Gary Sutton, Senior Vice President of Corporate Development for Pioneering Medicines, joined Flagship in July to lead Pioneering Medicines' partnering strategy and execution. Gary is an accomplished life-sciences corporate development and legal expert. He spent 16 years at Novartis Institutes for Biomedical Research (NIBR) and most recently led the team responsible for the structuring, negotiation and execution of all business development transactions and out-licensing activities.

Pioneering Medicines continues to expand its team with additional R&D expertise as it seeks to conceive and advance a portfolio of life-changing medicines for patients in need.

About Pioneering Medicines

Pioneering Medicines is conducting a live webinar about its strategy and innovative process on February 10, 2021.  To register for this event, click here.

For additional information, visit www.pioneeringmedicines.com.

About Flagship Pioneering

Flagship Pioneering conceives, creates, resources, and develops first-in-category life science platform companies to transform human health and sustainability. Since its launch in 2000, the firm has, through its Flagship Labs unit, applied its unique hypothesis-driven innovation process to originate and foster more than 100 scientific ventures, resulting in over $50 billion in aggregate value. To date, Flagship has deployed over $2.2 billion in capital toward the founding and growth of its pioneering companies alongside more than $18 billion of follow-on investments from other institutions. The current Flagship ecosystem comprises 41 transformative companies, including Axcella Health (NASDAQ: AXLA), Denali Therapeutics (NASDAQ: DNLI), Evelo Biosciences (NASDAQ: EVLO), Foghorn Therapeutics (NASDAQ:FHTX), Indigo Ag, Kaleido Biosciences (NASDAQ: KLDO), Moderna (NASDAQ: MRNA), Rubius Therapeutics (NASDAQ: RUBY), Sana Biotechnology, Seres Therapeutics (NASDAQ: MCRB), and Sigilon Therapeutics (NASDAQ:SGTX).

SOURCE Flagship Pioneering

Related Links

http://www.FlagshipPioneering.com

Modal title

Also from this source

Flagship Pioneering Unveils Inzen Therapeutics...


Flagship Pioneering Announces Appointment of Dr. Luciano Rossetti ...

Explore

More news releases in similar topics

  • Medical Pharmaceuticals
  • Health Care & Hospitals
  • Pharmaceuticals
  • Licensing

    Contact Cision

  • Cision Distribution 888-776-0942
    from 8 AM - 9 PM ET

  • Chat with an Expert
    • General Inquiries
    • Request a Demo
    • Editorial Bureaus
    • Partnerships
    • Media Inquiries
    • Worldwide Offices

    Products

  • Cision Communication Cloud®
  • For Marketers
  • For Public Relations
  • For IR & Compliance
  • For Agency
  • For Small Business
  • All Products

    About

  • About PR Newswire
  • About Cision
  • Become a Publishing Partner
  • Become a Channel Partner
  • Careers
  • COVID-19 Resources
  • Accessibility Statement

    • Asia
    • Brazil
    • Canada
    • Czech
    • Denmark
    • Finland
    • France
    • Germany
    • India
    • Israel
    • Italy
    • Mexico
    • Middle East
    • Netherlands
    • Norway
    • Poland
    • Portugal
    • Russia
    • Slovakia
    • Spain
    • Sweden
    • United Kingdom

    My Services

  • All New Releases
  • Online Member Center
  • ProfNet

Contact Cision


Products


About


My Services
  • All News Releases
  • Online Member Center
  • ProfNet℠
Cision Distribution Helpline
888-776-0942
  • Terms of Use
  • Privacy Policy
  • Information Security Policy
  • Site Map
  • RSS
  • Cookie Settings
Copyright © 2021 Cision US Inc.