Global Erythropoietin Drugs Market Research Report 2021-2027: Biologics, Biosimilars, Epoetin-alfa, Epoetin-beta, Darbepoetin-alfa

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Jul 07, 2021, 11:45 ET

DUBLIN, July 7, 2021 /PRNewswire/ -- The "Global Erythropoietin Drugs Market By Drug Class, By Product, By Application, By Regional Outlook, Industry Analysis Report and Forecast, 2021 - 2027" report has been added to ResearchAndMarkets.com's offering.

The Global Erythropoietin Drugs Market size is expected to reach $20.2 billion by 2027, rising at a market growth of 11.8% CAGR

Erythropoietin (EPO) also called hematopoietin is a glycoprotein hormone. It stimulates the process of erythropoiesis which results in the production of red blood cells in the bone marrow. The main goal for the development of erythropoietin drug was to treat anaemic conditions arising from end-stage renal disease (ESRD) disease.

Thus, it helps in treatments of this disease and dialysis procedures. Apart from its use in ESRD anaemic conditions, erythropoietin drugs also received approvals for chemotherapy-induced anaemia. The post-abbreviated new drug application (ANDA) is getting approvals and there is a high success rate of erythropoietin drugs in chemotherapy-induced anaemia. Due to all these factors, major biopharmaceutical companies turned their focus towards another form of induced anaemia, that is ART-induced anaemia which occurs mostly among the HIV patients.

Epoetin alfa (Epoge) is a kind of recombinant erythropoietin that was developed by Amgen Inc. in 1983. It was the first rhEPO that was commercialized in the United States, after alfa and beta formulations. Epoetin refers to an erythropoiesis-stimulating glycoprotein that is composed of a 165-amino acid. It is produced in cell culture based on recombinant DNA technology. This drug is used to treat patients suffering from anaemia and other blood-related clinical conditions like chronic renal failure, chemotherapy, and antiviral drug therapy. This drug is also recommended for patients who are at high risk for perioperative blood loss due to surgical procedures.

COVID-19 Impact

The COVID-19 resulted in the disruption of workflows in the health care sector across the world. A number of industries were forced to go for shutdown temporarily due to this outbreak. The main affected industry is the sub-domains of health care. Yet, it has positively affected the demand for medicines and increased the demand for several medical services, such as erythropoietin. The erythropoietin (EPO) drug is used to treat anaemia and works effectively against COVID-19.

This has been scientifically proved by scientists of the Max Planck Institute of Experimental Medicine in Gottingen. According to the research, the SARS-CoV-2 potentially attacks the brain, and erythropoietin can diminish serious disease development. Thus, it can protect people from the development of long-term neurological problems.

However, EPO is beneficial in many other diseases and has cytoprotective effects such as regenerative, anti-ischemic, and anti-apoptotic effects in tissues like lung, kidney, cardiac muscle, retina, pancreas, nervous system, and endothelial cells. Therefore, the impact of the COVID-19 pandemic is likely to have a positive impact on the erythropoietin drug market.

Drug Class Outlook

Based on Drug Class, the market is segmented into Biologics and Biosimilars. Based on Drug Class, the biologics erythropoietin segment dominated the market in 2020 because of the patent protection. Other factors driving the growth of this segment include the presence of a large patient population and increased uptake of biologics in various diseases. The availability of very few biologics in the market resulted in higher adoption of this drug.

Product Outlook

Based on Product, the market is segmented into Epoetin-alfa, Epoetin-beta, Darbepoetin-alfa and others. Epoetin-beta is a recombinant type of drug formed from epoetin-alfa. This product segment is growing owing to its benefits like improved efficacy and a longer half-life compared to the epoetin-alfa.

Darbepoetin-alfa is also a novel erythropoietin drug. It is developed by Amgen, Inc., marketed under the brand name Aranesp. Darbepoetin-alfa segment is likely to see positive growth during the forecast period. It is accredited to its higher efficacy, cost-effectiveness, and longer half-life. It is considered a feasible solution for the treatment of anaemia arising due to end-stage renal diseases.

Application Outlook

Based on Application, the market is segmented into Renal Diseases, Cancer, Hematology and Neurology. The cancer segment is expected to showcase fastest growth rate during the forecast period. It is due to the increasing cases of cancer incidence across the world. Cancer chemotherapy includes the utilization of medication which is capable of increasing the RBC count amongst patients. Thus, the usage of such drugs for chemotherapy has gained considerable attention in recent years. This has increased the demand for EPO drugs for cancer treatment that will act as a positive factor to augment the growth of this segment.

Key companies profiled in the report include

Johnson and Johnson
Teva Pharmaceuticals Industries Ltd.
Amgen, Inc.
F. Hoffmann-La Roche Ltd.
Biocon Limited
Intas Pharmaceutical Ltd.
Sun Pharmaceutical Industries Ltd.
Dr. Reddy's Laboratories Ltd.
LG Corporation (LG Life Sciences Ltd.)
Celltrion, Inc.

Key Topics Covered:

Chapter 1. Market Scope & Methodology

Chapter 2. Market Overview
2.1 Introduction
2.2 Key Factors Impacting the Market

Chapter 3. Global Erythropoietin Drugs Market by Drug Class
3.1 Global Biologics Market by Region
3.2 Global Biosimilars Market by Region

Chapter 4. Global Erythropoietin Drugs Market by Product
4.1 Global Epoetin-alfa Market by Region
4.2 Global Epoetin-beta Market by Region
4.3 Global Darbepoetin-alfa Market by Region
4.4 Global Other Product Market by Region

Chapter 5. Global Erythropoietin Drugs Market by Application
5.1 Global Renal Diseases Market by Region
5.2 Global Cancer Market by Region
5.3 Global Hematology Market by Region
5.4 Global Neurology Market by Region

Chapter 6. Global Erythropoietin Drugs Market by Region

Chapter 7. Company Profiles