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Human Microbiome Therapeutics Market size to grow at a CAGR of 30.11% from 2022 to 2027 | Increase in industry-academia collaboration for the development of novel therapeutics is a major trend- Technavio

Global Human Microbiome Therapeutics Market

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Technavio

Aug 02, 2023, 12:45 ET

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NEW YORK, Aug. 2, 2023 /PRNewswire/ -- The human microbiome therapeutics market size is estimated to increase by USD 732.95 million from 2022 to 2027, at a CAGR of 30.11%, according to a recent market study by Technavio. This report also offers a 5-year historical (2017-2021) data projection of market size, segmentation, and region. Discover some insights on market size before buying the full report -Request a sample report

Human Microbiome Therapeutics Market 2023-2027 – Vendor Scope

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Technavio has announced its latest market research report titled Global Human Microbiome Therapeutics Market
Technavio has announced its latest market research report titled Global Human Microbiome Therapeutics Market

The human microbiome therapeutics market report also offers information on the criticality of inputs, R&D, CAPEX, technology, and products of 15 companies listed below -

4D Pharma Plc, BiomX Inc., Eligo Bioscience, ENTEROME SA, Evelo Biosciences Inc., Evogene Ltd., Ferring BV, Finch Therapeutics Group Inc., Flightpath Biosciences, Johnson and Johnson Services Inc., MaaT Pharma, Microbiotica Ltd., OptiBiotix Health Plc, PureTech Health Plc, Second Genome Therapeutics, Seres Therapeutics Inc., Synlogic Inc., Takeda Pharmaceutical Co. Ltd., YSOPIA Bioscience, and Locus Biosciences Inc. Download a Sample Report

Chart & Data Table on 5-Year Historic (2017-2021) Market Size, Comparative Analysis of Segments, and Y-O-Y Growth of Human microbiome therapeutics market

Human Microbiome Therapeutics Market 2023-2027: Segmentation

The market is segmented by product (probiotics, prebiotics, medical foods, and prescription drugs), application (gastrointestinal disorders, infectious diseases, and others), and geography (North America, Europe, Asia, and the Rest of the World (ROW))

  • The market share of the probiotics segment is estimated to witness significant growth during the forecast period. Probiotics are living microbes that, when given in sufficient quantities, boost the host's health. Probiotics are bacteria and yeast that support a balanced microbial environment in human intestines. They are generally found in yogurt and other fermented foods. Additionally, they improve the immune system and shield lipids and proteins from oxidative damage. Hence, these factors are expected to drive segment growth during the forecast period.
  • North America is estimated to contribute 41% to the growth of the global market during the forecast period. However, the region is expected to be slower than Europe and Asia. The market in the region is driven by factors such as significant investments in R & D for the development of novel therapeutic procedures and a high prevalence of gastrointestinal, metabolic, and immunological illnesses. Hence, these factors are expected to drive segment growth during the forecast period.

To procure the data - Buy the report!

Human Microbiome Therapeutics Market 2023-2027 – Market Dynamics

Key Driver

The growing prevalence of chronic diseases is a key factor driving market growth. These diseases also lead to the development of other serious diseases which include diabetes, hypertension, and obesity. Hypertension can also be caused by improper lifestyle choices and genetic factors. High blood pressure usually causes no symptoms. In addition, studies have shown that obese middle-aged men have a 50 to 60% higher risk of heart failure than nonobese middle-aged men. Hence, these factors are expected to drive market growth during the forecast period.

Major Trends

The increase in industry-academia collaboration for the development of novel therapeutics is a major trend in the market. To support the R&D of novel medicines for the treatment of diabetes, the major companies in the global pharmaceutical drugs industry are increasingly extending their assistance to academic institutions. Collaborations between businesses and academic institutions make it possible to combine the marketing knowledge of pharmaceutical companies with the scientific competence of academic organizations. Hence, this trend is expected to drive market growth during the forecast period.

Significant Challenges

The indiscriminate use of antibiotics is a significant challenge restricting market growth. In primary care, where viruses typically cause infections, overprescribing of antibiotics is a problem. The already overcrowded healthcare system incurs additional costs because of antibiotic resistance because it reduces both the number of medications that may be used for treatment and the long-term efficacy of the currently available drugs. But indiscriminate antibiotic use harms our body's natural flora and interferes with the effectiveness of microbial medicinal medicines. Hence, the above-mentioned factors are expected to restrict market growth during the forecast period.

For Insights on the market dynamics & segmentations VIEW PDF SAMPLE!

What are the key data covered in this Human Microbiome Therapeutics Market report?

  • CAGR of the market during the forecast period
  • Detailed information on factors that will drive the growth of the human microbiome therapeutics market between 2023 and 2027
  • Precise estimation of the size of the human microbiome therapeutics market and its contribution to the market with a focus on the parent market
  • Accurate predictions about upcoming trends and changes in consumer behavior
  • Growth of the human microbiome therapeutics market across North America, Europe, Asia, and Rest of the World (ROW)
  • A thorough analysis of the market's competitive landscape and detailed information about companies
  • Comprehensive analysis of factors that will challenge the growth of human microbiome therapeutics market companies.

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Human Microbiome Therapeutics Market Scope

Report Coverage

Details

Base year

2022

Historic period

2017-2021

Forecast period

2023-2027

Growth momentum & CAGR

Accelerate at a CAGR of 30.11%

Market growth 2023-2027

USD 732.95 million

Market structure

Fragmented

YoY growth 2022-2023 (%)

28.29

Regional analysis

North America, Europe, Asia, and the Rest of the World (ROW)

Performing market contribution

North America at 41%

Key countries

US, Germany, France, UK, and Japan

Competitive landscape

Leading Companies, Market Positioning of Companies, Competitive Strategies, and Industry Risks

Key companies profiled

4D pharma Plc, BiomX Inc., Eligo Bioscience, ENTEROME SA, Evelo Biosciences Inc., Evogene Ltd., Ferring BV, Finch Therapeutics Group Inc., Flightpath Biosciences, Johnson and Johnson Services Inc., MaaT Pharma, Microbiotica Ltd., OptiBiotix Health Plc, PureTech Health Plc, Second Genome Therapeutics, Seres Therapeutics Inc., Synlogic Inc., Takeda Pharmaceutical Co. Ltd., YSOPIA Bioscience, and Locus Biosciences Inc.

Market dynamics

Parent market analysis, Market growth inducers and obstacles, Fast-growing and slow-growing segment analysis, COVID-19 impact and recovery analysis and future consumer dynamics, and Market condition analysis for the forecast period.

Customization purview

If our report has not included the data that you are looking for, you can reach out to our analysts and get segments customized.

Table of Contents

1 Executive Summary

  • 1.1 Market Overview
    • Exhibit 01: Executive Summary – Chart on Market Overview
    • Exhibit 02: Executive Summary – Data Table on Market Overview
    • Exhibit 03: Executive Summary – Chart on Global Market Characteristics
    • Exhibit 04: Executive Summary – Chart on Market by Geography
    • Exhibit 05: Executive Summary – Chart on Market Segmentation by Product
    • Exhibit 06: Executive Summary – Chart on Market Segmentation by Application
    • Exhibit 07: Executive Summary – Chart on Incremental Growth
    • Exhibit 08: Executive Summary – Data Table on Incremental Growth
    • Exhibit 09: Executive Summary – Chart on Vendor Market Positioning

2 Market Landscape

  • 2.1 Market ecosystem
    • Exhibit 10: Parent market
    • Exhibit 11: Market Characteristics

3 Market Sizing

  • 3.1 Market definition
    • Exhibit 12: Offerings of companies included in the market definition
  • 3.2 Market segment analysis 
    • Exhibit 13: Market segments
  • 3.3 Market size 2022
  • 3.4 Market outlook: Forecast for 2022-2027 
    • Exhibit 14: Chart on Global - Market size and forecast 2022-2027 ($ million)
    • Exhibit 15: Data Table on Global - Market size and forecast 2022-2027 ($ million)
    • Exhibit 16: Chart on Global Market: Year-over-year growth 2022-2027 (%)
    • Exhibit 17: Data Table on Global Market: Year-over-year growth 2022-2027 (%)

4 Historic Market Size

  • 4.1 Global human microbiome therapeutics market 2017 - 2021 
    • Exhibit 18: Historic Market Size – Data Table on global human microbiome therapeutics market 2017 - 2021 ($ million)
  • 4.2 Product Segment Analysis 2017 - 2021 
    • Exhibit 19: Historic Market Size – Product Segment 2017 - 2021 ($ million)
  • 4.3 Application Segment Analysis 2017 - 2021 
    • Exhibit 20: Historic Market Size – Application Segment 2017 - 2021 ($ million)
  • 4.4 Geography Segment Analysis 2017 - 2021 
    • Exhibit 21: Historic Market Size – Geography Segment 2017 - 2021 ($ million)
  • 4.5 Country Segment Analysis 2017 - 2021 
    • Exhibit 22: Historic Market Size – Country Segment 2017 - 2021 ($ million)

5 Five Forces Analysis

  • 5.1 Five forces summary
    • Exhibit 23: Five forces analysis - Comparison between 2022 and 2027
  • 5.2 Bargaining power of buyers 
    • Exhibit 24: Chart on Bargaining power of buyers – Impact of key factors 2022 and 2027
  • 5.3 Bargaining power of suppliers 
    • Exhibit 25: Bargaining power of suppliers – Impact of key factors in 2022 and 2027
  • 5.4 Threat of new entrants 
    • Exhibit 26: Threat of new entrants – Impact of key factors in 2022 and 2027
  • 5.5 Threat of substitutes 
    • Exhibit 27: Threat of substitutes – Impact of key factors in 2022 and 2027
  • 5.6 Threat of rivalry
    • Exhibit 28: Threat of rivalry – Impact of key factors in 2022 and 2027
  • 5.7 Market condition
    • Exhibit 29: Chart on Market condition - Five forces 2022 and 2027

6 Market Segmentation by Product

  • 6.1 Market segments
    • Exhibit 30: Chart on Product - Market share 2022-2027 (%)
    • Exhibit 31: Data Table on Product - Market share 2022-2027 (%)
  • 6.2 Comparison by Product 
    • Exhibit 32: Chart on Comparison by Product
    • Exhibit 33: Data Table on Comparison by Product
  • 6.3 Probiotics - Market size and forecast 2022-2027 
    • Exhibit 34: Chart on Probiotics - Market size and forecast 2022-2027 ($ million)
    • Exhibit 35: Data Table on Probiotics - Market size and forecast 2022-2027 ($ million)
    • Exhibit 36: Chart on Probiotics - Year-over-year growth 2022-2027 (%)
    • Exhibit 37: Data Table on Probiotics - Year-over-year growth 2022-2027 (%)
  • 6.4 Prebiotics - Market size and forecast 2022-2027 
    • Exhibit 38: Chart on Prebiotics - Market size and forecast 2022-2027 ($ million)
    • Exhibit 39: Data Table on Prebiotics - Market size and forecast 2022-2027 ($ million)
    • Exhibit 40: Chart on Prebiotics - Year-over-year growth 2022-2027 (%)
    • Exhibit 41: Data Table on Prebiotics - Year-over-year growth 2022-2027 (%)
  • 6.5 Medical foods - Market size and forecast 2022-2027 
    • Exhibit 42: Chart on Medical foods - Market size and forecast 2022-2027 ($ million)
    • Exhibit 43: Data Table on Medical foods - Market size and forecast 2022-2027 ($ million)
    • Exhibit 44: Chart on Medical foods - Year-over-year growth 2022-2027 (%)
    • Exhibit 45: Data Table on Medical foods - Year-over-year growth 2022-2027 (%)
  • 6.6 Prescription drugs - Market size and forecast 2022-2027 
    • Exhibit 46: Chart on Prescription drugs - Market size and forecast 2022-2027 ($ million)
    • Exhibit 47: Data Table on Prescription drugs - Market size and forecast 2022-2027 ($ million)
    • Exhibit 48: Chart on Prescription drugs - Year-over-year growth 2022-2027 (%)
    • Exhibit 49: Data Table on Prescription drugs - Year-over-year growth 2022-2027 (%)
  • 6.7 Market opportunity by Product 
    • Exhibit 50: Market opportunity by Product ($ million)
    • Exhibit 51: Data Table on Market opportunity by Product ($ million)

7 Market Segmentation by Application

  • 7.1 Market segments
    • Exhibit 52: Chart on Application - Market share 2022-2027 (%)
    • Exhibit 53: Data Table on Application - Market share 2022-2027 (%)
  • 7.2 Comparison by Application 
    • Exhibit 54: Chart on Comparison by Application
    • Exhibit 55: Data Table on Comparison by Application
  • 7.3 Gastrointestinal disorders - Market size and forecast 2022-2027 
    • Exhibit 56: Chart on Gastrointestinal disorders - Market size and forecast 2022-2027 ($ million)
    • Exhibit 57: Data Table on Gastrointestinal disorders - Market size and forecast 2022-2027 ($ million)
    • Exhibit 58: Chart on Gastrointestinal disorders - Year-over-year growth 2022-2027 (%)
    • Exhibit 59: Data Table on Gastrointestinal disorders - Year-over-year growth 2022-2027 (%)
  • 7.4 Infectious diseases - Market size and forecast 2022-2027 
    • Exhibit 60: Chart on Infectious diseases - Market size and forecast 2022-2027 ($ million)
    • Exhibit 61: Data Table on Infectious diseases - Market size and forecast 2022-2027 ($ million)
    • Exhibit 62: Chart on Infectious diseases - Year-over-year growth 2022-2027 (%)
    • Exhibit 63: Data Table on Infectious diseases - Year-over-year growth 2022-2027 (%)
  • 7.5 Others - Market size and forecast 2022-2027 
    • Exhibit 64: Chart on Others - Market size and forecast 2022-2027 ($ million)
    • Exhibit 65: Data Table on Others - Market size and forecast 2022-2027 ($ million)
    • Exhibit 66: Chart on Others - Year-over-year growth 2022-2027 (%)
    • Exhibit 67: Data Table on Others - Year-over-year growth 2022-2027 (%)
  • 7.6 Market opportunity by Application 
    • Exhibit 68: Market opportunity by Application ($ million)
    • Exhibit 69: Data Table on Market opportunity by Application ($ million)

8 Customer Landscape

  • 8.1 Customer landscape overview 
    • Exhibit 70: Analysis of price sensitivity, lifecycle, customer purchase basket, adoption rates, and purchase criteria

9 Geographic Landscape

  • 9.1 Geographic segmentation 
    • Exhibit 71: Chart on Market share by geography 2022-2027 (%)
    • Exhibit 72: Data Table on Market share by geography 2022-2027 (%)
  • 9.2 Geographic comparison 
    • Exhibit 73: Chart on Geographic comparison
    • Exhibit 74: Data Table on Geographic comparison
  • 9.3 North America - Market size and forecast 2022-2027 
    • Exhibit 75: Chart on North America - Market size and forecast 2022-2027 ($ million)
    • Exhibit 76: Data Table on North America - Market size and forecast 2022-2027 ($ million)
    • Exhibit 77: Chart on North America - Year-over-year growth 2022-2027 (%)
    • Exhibit 78: Data Table on North America - Year-over-year growth 2022-2027 (%)
  • 9.4 Europe - Market size and forecast 2022-2027 
    • Exhibit 79: Chart on Europe - Market size and forecast 2022-2027 ($ million)
    • Exhibit 80: Data Table on Europe - Market size and forecast 2022-2027 ($ million)
    • Exhibit 81: Chart on Europe - Year-over-year growth 2022-2027 (%)
    • Exhibit 82: Data Table on Europe - Year-over-year growth 2022-2027 (%)
  • 9.5 Asia - Market size and forecast 2022-2027 
    • Exhibit 83: Chart on Asia - Market size and forecast 2022-2027 ($ million)
    • Exhibit 84: Data Table on Asia - Market size and forecast 2022-2027 ($ million)
    • Exhibit 85: Chart on Asia - Year-over-year growth 2022-2027 (%)
    • Exhibit 86: Data Table on Asia - Year-over-year growth 2022-2027 (%)
  • 9.6 Rest of World (ROW) - Market size and forecast 2022-2027 
    • Exhibit 87: Chart on Rest of World (ROW) - Market size and forecast 2022-2027 ($ million)
    • Exhibit 88: Data Table on Rest of World (ROW) - Market size and forecast 2022-2027 ($ million)
    • Exhibit 89: Chart on Rest of World (ROW) - Year-over-year growth 2022-2027 (%)
    • Exhibit 90: Data Table on Rest of World (ROW) - Year-over-year growth 2022-2027 (%)
  • 9.7 US - Market size and forecast 2022-2027 
    • Exhibit 91: Chart on US - Market size and forecast 2022-2027 ($ million)
    • Exhibit 92: Data Table on US - Market size and forecast 2022-2027 ($ million)
    • Exhibit 93: Chart on US - Year-over-year growth 2022-2027 (%)
    • Exhibit 94: Data Table on US - Year-over-year growth 2022-2027 (%)
  • 9.8 Germany - Market size and forecast 2022-2027 
    • Exhibit 95: Chart on Germany - Market size and forecast 2022-2027 ($ million)
    • Exhibit 96: Data Table on Germany - Market size and forecast 2022-2027 ($ million)
    • Exhibit 97: Chart on Germany - Year-over-year growth 2022-2027 (%)
    • Exhibit 98: Data Table on Germany - Year-over-year growth 2022-2027 (%)
  • 9.9 France - Market size and forecast 2022-2027 
    • Exhibit 99: Chart on France - Market size and forecast 2022-2027 ($ million)
    • Exhibit 100: Data Table on France - Market size and forecast 2022-2027 ($ million)
    • Exhibit 101: Chart on France - Year-over-year growth 2022-2027 (%)
    • Exhibit 102: Data Table on France - Year-over-year growth 2022-2027 (%)
  • 9.10 UK - Market size and forecast 2022-2027 
    • Exhibit 103: Chart on UK - Market size and forecast 2022-2027 ($ million)
    • Exhibit 104: Data Table on UK - Market size and forecast 2022-2027 ($ million)
    • Exhibit 105: Chart on UK - Year-over-year growth 2022-2027 (%)
    • Exhibit 106: Data Table on UK - Year-over-year growth 2022-2027 (%)
  • 9.11 Japan - Market size and forecast 2022-2027 
    • Exhibit 107: Chart on Japan - Market size and forecast 2022-2027 ($ million)
    • Exhibit 108: Data Table on Japan - Market size and forecast 2022-2027 ($ million)
    • Exhibit 109: Chart on Japan - Year-over-year growth 2022-2027 (%)
    • Exhibit 110: Data Table on Japan - Year-over-year growth 2022-2027 (%)
  • 9.12 Market opportunity by geography 
    • Exhibit 111: Market opportunity by geography ($ million)
    • Exhibit 112: Data Tables on Market opportunity by geography ($ million)

10 Drivers, Challenges, and Trends

  • 10.1 Market drivers
  • 10.2 Market challenges
  • 10.3 Impact of drivers and challenges 
    • Exhibit 113: Impact of drivers and challenges in 2022 and 2027
  • 10.4 Market trends

11 Vendor Landscape

  • 11.1 Overview
  • 11.2 Vendor landscape
    • Exhibit 114: Overview on Criticality of inputs and Factors of differentiation
  • 11.3 Landscape disruption
    • Exhibit 115: Overview on factors of disruption
  • 11.4 Industry risks
    • Exhibit 116: Impact of key risks on business

12 Vendor Analysis

  • 12.1 Companies covered 
    • Exhibit 117: Companiescovered
  • 12.2 Market positioning of companies 
    • Exhibit 118: Matrix on vendor position and classification
  • 12.3 4D pharma Plc
    • Exhibit 119: 4D pharma Plc - Overview
    • Exhibit 120: 4D pharma Plc - Product / Service
    • Exhibit 121: 4D pharma Plc - Key offerings
  • 12.4 BiomX Inc.
    • Exhibit 122: BiomX Inc. - Overview
    • Exhibit 123: BiomX Inc. - Product / Service
    • Exhibit 124: BiomX Inc. - Key offerings
  • 12.5 Eligo Bioscience
    • Exhibit 125: Eligo Bioscience - Overview
    • Exhibit 126: Eligo Bioscience - Product / Service
    • Exhibit 127: Eligo Bioscience - Key offerings
  • 12.6 ENTEROME SA
    • Exhibit 128: ENTEROME SA - Overview
    • Exhibit 129: ENTEROME SA - Product / Service
    • Exhibit 130: ENTEROME SA - Key offerings
  • 12.7 Evelo Biosciences Inc. 
    • Exhibit 131: Evelo Biosciences Inc. - Overview
    • Exhibit 132: Evelo Biosciences Inc. - Product / Service
    • Exhibit 133: Evelo Biosciences Inc. - Key offerings
  • 12.8 Evogene Ltd.
    • Exhibit 134: Evogene Ltd. - Overview
    • Exhibit 135: Evogene Ltd. - Business segments
    • Exhibit 136: Evogene Ltd. - Key offerings
    • Exhibit 137: Evogene Ltd. - Segment focus
  • 12.9 Ferring BV
    • Exhibit 138: Ferring BV - Overview
    • Exhibit 139: Ferring BV - Product / Service
    • Exhibit 140: Ferring BV - Key offerings
  • 12.10 Finch Therapeutics Group Inc. 
    • Exhibit 141: Finch Therapeutics Group Inc. - Overview
    • Exhibit 142: Finch Therapeutics Group Inc. - Product / Service
    • Exhibit 143: Finch Therapeutics Group Inc. - Key offerings
  • 12.11 Johnson and Johnson Services Inc. 
    • Exhibit 144: Johnson and Johnson Services Inc. - Overview
    • Exhibit 145: Johnson and Johnson Services Inc. - Business segments
    • Exhibit 146: Johnson and Johnson Services Inc. - Key news
    • Exhibit 147: Johnson and Johnson Services Inc. - Key offerings
    • Exhibit 148: Johnson and Johnson Services Inc. - Segment focus
  • 12.12 OptiBiotix Health Plc 
    • Exhibit 149: OptiBiotix Health Plc - Overview
    • Exhibit 150: OptiBiotix Health Plc - Product / Service
    • Exhibit 151: OptiBiotix Health Plc - Key offerings
  • 12.13 PureTech Health Plc
    • Exhibit 152: PureTech Health Plc - Overview
    • Exhibit 153: PureTech Health Plc - Business segments
    • Exhibit 154: PureTech Health Plc - Key offerings
    • Exhibit 155: PureTech Health Plc - Segment focus
  • 12.14 Second Genome Therapeutics 
    • Exhibit 156: Second Genome Therapeutics - Overview
    • Exhibit 157: Second Genome Therapeutics - Product / Service
    • Exhibit 158: Second Genome Therapeutics - Key offerings
  • 12.15 Seres Therapeutics Inc. 
    • Exhibit 159: Seres Therapeutics Inc. - Overview
    • Exhibit 160: Seres Therapeutics Inc. - Product / Service
    • Exhibit 161: Seres Therapeutics Inc. - Key offerings
  • 12.16 Synlogic Inc.
    • Exhibit 162: Synlogic Inc. - Overview
    • Exhibit 163: Synlogic Inc. - Product / Service
    • Exhibit 164: Synlogic Inc. - Key offerings
  • 12.17 Takeda Pharmaceutical Co. Ltd. 
    • Exhibit 165: Takeda Pharmaceutical Co. Ltd. - Overview
    • Exhibit 166: Takeda Pharmaceutical Co. Ltd. - Product / Service
    • Exhibit 167: Takeda Pharmaceutical Co. Ltd. - Key news
    • Exhibit 168: Takeda Pharmaceutical Co. Ltd. - Key offerings

13 Appendix

  • 13.1 Scope of the report
  • 13.2 Inclusions and exclusions checklist 
    • Exhibit 169: Inclusions checklist
    • Exhibit 170: Exclusions checklist
  • 13.3 Currency conversion rates for US$ 
    • Exhibit 171: Currency conversion rates for US$
  • 13.4 Research methodology
    • Exhibit 172: Research methodology
    • Exhibit 173: Validation techniques employed for market sizing
    • Exhibit 174: Information sources
  • 13.5 List of abbreviations
    • Exhibit 175: List of abbreviations

About Us
Technavio is a leading global technology research and advisory company. Their research and analysis focus on emerging market trends and provide actionable insights to help businesses identify market opportunities and develop effective strategies to optimize their market positions. With over 500 specialized analysts, Technavio's report library consists of more than 17,000 reports and counting, covering 800 technologies, spanning 50 countries. Their client base consists of enterprises of all sizes, including more than 100 Fortune 500 companies. This growing client base relies on Technavio's comprehensive coverage, extensive research, and actionable market insights to identify opportunities in existing and potential markets and assess their competitive positions within changing market scenarios.

Contact
Technavio Research
Jesse Maida
Media & Marketing Executive
US: +1 844 364 1100
UK: +44 203 893 3200
Email: [email protected]
Website: www.technavio.com

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