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JNCCN的新研究发现,胰腺癌患者的治疗和生存时间存在明显差异
  • USA - Traditional Chinese
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NCCN徽标(C)NCCN(R)2018。 保留所有权利。

News provided by

National Comprehensive Cancer Network

Apr 09, 2025, 10:12 ET

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俄亥俄州立大学韦克斯纳医学中心和詹姆斯综合癌症中心的研究人员发现,社会弱势的转移性胰腺癌患者接受高质量护理的可能性明显较低,生存率较差。

宾夕法尼亚州普利茅斯米廷2025年4月9日 /美通社/ -- 2025年4月期刊  JNCCN-Journal of the National Comprehensive Cancer Network 的新研究发现,在转移性胰腺癌( mPDAC )患者的护理质量和转归方面,基于种族、社会经济地位和其他因素,存在显著差异,这与癌症死亡率非常高有关。 研究人员使用监测、流行病学和最终结果( SEER ) -Medicare数据库研究了2005-2019年期间被诊断患有mPDAC的14,147名患者。 质量评分是根据1 )指南一致的全身治疗、2 )姑息治疗和3 )癌症特异性生存期超过12个月的患者确定的。

社会脆弱性指数( SVI )测量值较高的患者至少体验三项质量指标之一的可能性降低30%。 值得注意的是,当种族和经济状况分开时,无论收入如何,属于服务不足的种族或族裔群体的个人体验一个或多个质量指标的可能性降低了25%。 较低的社会经济地位与体验质量指标的机会降低34%相关,与种族无关。

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封面, JNCCN 2025年4月。 如需阅读最新期刊,请访问JNCCN.org。
封面, JNCCN 2025年4月。 如需阅读最新期刊,请访问JNCCN.org。

主要作者 Diamantis Tsilimigras, MD, PhD, 俄亥俄州立大学韦克斯纳医学中心和詹姆斯综合癌症中心表示: “我们的研究结果重点表明,需要有针对性的干预措施来缓解癌症护理方面的差异。” “扩大医疗补助或可能扩大姑息治疗的医疗保险覆盖范围的联邦政策可以帮助减少差距。 此外,解决健康的社会决定因素的政策--包括对最弱势群体的财政援助,以及理解和解决与治疗建议相关的潜在隐性偏见--可以帮助解决平等获得护理方面的差距。”

该研究发现,接受适当的全身和/或姑息治疗的患者在诊断后更有可能存活超过一年。 他们还发现,在2005年至2019年的研究期间,质量评分和寿命都有所改善。

资深作者 Timothy M. Pawlik, MD, PhD, MPH, MTS, MBA, 俄亥俄州立大学韦克斯纳医学中心和詹姆斯综合癌症中心补充道: “确保所有患者,无论其背景如何,都能获得与指南一致的护理对于改善转移性胰腺癌患者的预后非常重要。” “我们发现,虽然对NCCN指南的依从性随着时间的推移而提高,但在转移性胰腺癌患者接受指南一致性护理方面仍存在显著差异,这反过来又会影响结局。”

哈佛医学院外科副教授、医学博士Jason S. Gold 没有参与这项研究,他评论道: “人们越来越认识到胰腺癌治疗和结果的差异持续存在。 这项研究增加了这一知识体系,表明社会脆弱性、未婚地位和较低收入都与转移性胰腺导管腺癌的低质量护理独立相关。"

Gold博士是这项研究的较长回应的作者,也可以在 JNCCN的4月期刊上找到。要阅读整个研究“ 转移性胰腺癌患者的质量评分:趋势、种族差异和对结局的影响”和相应的“ 最后一句话”评论,请访问 JNCCN.org 。

关于 JNCCN-国家综合癌症网络期刊
美国更多的25,000名肿瘤学家和其他癌症护理专业人士阅读 JNCCN-国家综合癌症网络期刊。 这本同行评审的索引医学期刊提供有关转化医学创新的最新信息,以及与肿瘤学健康服务研究相关的科学研究,包括优质护理和价值、生物伦理、比较和成本效益、公共政策以及支持性护理和幸存者介入研究。  JNCCN 对《NCCN肿瘤学临床实践指南》( NCCN指南 ® )进行了更新,对指南建议、卫生服务研究和病例报告进行了综述,重点介绍了患者护理中的分子见解。  JNCCN 由Harborside/BroadcastMed出版。 访问 JNCCN.org 。 如需了解您是否有资格获得 JNCCN 的 免费订阅,请访问 NCCN.org/jnccn/subscribe 。 通过 x.com/JNCCN 关注 JNCCN 。

关于国家综合癌症网络
国家综合癌症网络 ® ( NCCN ® )成立30周年,是一家由 领先的癌症中心 组成的非营利联盟,致力于患者护理、研究和教育。 NCCN致力于定义和推进优质、有效、公平且可及的癌症护理和预防,让所有人都能过上更好的生活。 《NCCN肿瘤学临床实践指南》( NCCN指南 ® )为癌症治疗、预防和支持服务提供了透明、循证、获得专家共识的建议,是癌症管理中临床指导和政策制定的公认标准,也是医学领域中最为详尽和更新频率最快的临床实践指南。 NCCN Guidelines for Patients®(《NCCN患者指南》)在NCCN Foundation®(NCCN基金会)的支持下,提供专业的癌症治疗信息,旨在告知并赋予患者和护理人员更多的知识和力量。 NCCN还推动肿瘤学领域的继续教育、全球倡议、政策制定、研究合作以及出版工作。 如需更多信息,请访问 NCCN.org 。

媒体联系人:
Rachel Darwin
267-622-6624
[email protected]

National Comprehensive Cancer Network

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