SAN FRANCISCO, May 16, 2016 /PRNewswire/ -- Kindred Biosciences, Inc. (NASDAQ: KIN), a biopharmaceutical company focused on saving and improving the lives of pets, today announced positive topline results from its pivotal field study of KIND-010, mirtazapine transdermal gel, for the management of weight loss in cats.
This study, KB105, was a multicenter, randomized, double-blind, placebo-controlled pivotal field study that enrolled 231 cats to assess the effectiveness of KIND-010 in stimulating weight gain in cats. The primary endpoint was percentage change in body weight from Day 1 to Week 2. At Week 2, the mean percent increase in body weight from Day 1 was 4.07% in the KIND-010 group (n=90), versus 0.29% in the placebo group (n=97) (p<0.0001). Based on a preliminary review of the safety data, the drug appears to be well tolerated.
"I would like to thank the KindredBio team and our investigators. Inappetence in cats is a serious disease, and is one of the leading causes of veterinary visits among cat owners. We are very pleased to advance this drug closer to approval. The pivotal study was completed on budget and ahead of schedule, underscoring our ability to develop therapeutics that improve the lives of companion animals quickly and in a cost-efficient manner," said Richard Chin, M.D., President and Chief Executive Officer. "We look forward to continuing to build on our successes."
The Company plans to file the Effectiveness Technical Section with the data from the KB105 pivotal field study with the Food and Drug Administration (FDA) in the third quarter of 2016. KindredBio has already filed the Chemistry, Manufacturing, and Controls technical section of the New Animal Drug Application with the FDA and completed the in-life portion of the Target Animal Safety Study successfully.
Conference Call and Webcast
KindredBio will host a conference call and webcast today at 4:30 p.m. Eastern Time / 1:30 p.m. Pacific Time. Interested parties may access the call by dialing toll-free (855) 433-0927 from the US, or (484) 756-4262 internationally, and using conference ID 12596310. The call will also be webcast live at http://edge.media-server.com/m/p/2fukht6k. A replay will also be available at that link for 30 days.
About Inappetence in Cats
Inappetence is a serious unmet medical need in cats, and may be caused by multiple factors, including chronic illness or infection. If untreated, it may lead to hepatic failure, which can be a life-threatening condition. Inappetence is common in cats, especially in older cats. On average, a small animal veterinarian may see up to 7 cats per week with the condition.
About Kindred Biosciences
Kindred Biosciences is a development-stage biopharmaceutical company focused on saving and improving the lives of pets. Its mission is to bring to pets the same kinds of safe and effective medicines that human family members enjoy. The Company's strategy is to identify compounds and targets that have already demonstrated safety and efficacy in humans and to develop therapeutics based on these validated compounds and targets for dogs, cats, and horses. The Company has a deep pipeline of novel drugs and biologics in development across many therapeutic classes. www.kindredbio.com
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SOURCE Kindred Biosciences, Inc.