MINNEAPOLIS, June 4, 2014 /PRNewswire/ - IMRIS Inc. (NASDAQ: IMRS; TSX: IM)
("IMRIS" or the "Company") today announced that a published
retrospective study indicates that use of VISIUS intraoperative MRI
(iMRI) combined with endoscopy for transsphenoidal surgery (surgical
access through the nose) increases the amount of pituitary (adenoma)
tumor removal compared to conventional microscopy without iMRI. The
amount of tumor removal using iMRI was also associated with longer
patient survival, according to the article.
The retrospective study comparing 446 patients at Barnes-Jewish Hospital
in St. Louis published online in the journal Pituitary showed that iMR revealed that tumor removal was incomplete for 56 out of
156 patients (35.9 percent). Since this additional tumor was discovered
by intraoperative MR rather than postoperative MR, the surgery was able
to continue to remove additional tumor. For 15 of these patients (or
9.6 percent), the article states, this additional tumor removal changed
their outcome classification which significantly improved the
progression-free survival rate for these patients.
"We found in this analyses that the endoscopy and iMRI have a
complementary role in increasing resection in procedures with
transsphenenoidal approaches," said Dr. Michael Chicoine, one of the
study authors and associate professor of neurosurgery at the Washington
University School of Medicine. "While follow up of our patients is
ongoing, the data suggest that extent of resection can be used as a
suitable measure of long-term survival and quality of life."
The extent of tumor removal results are similar to published studies
focused on removing brain tumors accessed through the skull which
report that in 55% of glioma tumor cases, the surgeon resected
additional tumor after iMRI. In addition, a 2011 iMRI study led by Dr.
Chicoine showed that 93 percent of iMRI cases had gross total resection
while 65 percent of non-iMRI surgeries achieved total resection.
This pituitary tumor analyses was the largest study using iMRI and
endoscopy together and the first using a VISIUS Surgical Theatre -
where surgeons have on-demand access to real-time data and diagnostic
quality imaging during the procedure from the OR table. Patient
transport for imaging is eliminated with VISIUS iMRI as the scanner
uniquely moves to the patient on ceiling-mounted rails. With imaging
more accessible during surgery, it is more likely to be incorporated
into the procedure.
IMRIS CEO and President Jay D. Miller added, "This study provides more
evidence of the impact and value of intraoperative MR, especially with
the diagnostic quality imaging only IMRIS can provide during surgery
without moving the patient. We continue to work with leading
neuroscience centers to find ways to enable new neurosurgical
techniques and procedures to improve patient outcomes."
IMRIS supports ongoing studies and research regarding the use and
benefits of ceiling-mounted iMRI through an expanding Washington
University School of Medicine multicenter neurosurgical database called
I-MiND (IMRIS Multicenter iMRI Neurosurgery Database) which includes a
growing number of leading hospitals. In addition, IMRIS produces
proprietary head fixation devices, imaging coils, and OR tables for use
in this unique and multifunctional intraoperative environment.
Published online on March 6 in the journal Pituitary, the article is titled: "Combined high-field intraoperative magnetic
resonance imaging and endoscopy increase extent of resection and
progression-free survival for pituitary adenomas." Information on the
article can be found: http://www.ncbi.nlm.nih.gov/pubmed/24599833.
About IMRIS IMRIS (NASDAQ: IMRS; TSX: IM) is a global leader in providing image
guided therapy solutions through its VISIUS Surgical Theatre - a
revolutionary, multifunctional surgical environment that provides
unmatched intraoperative vision to clinicians to assist in decision
making and enhance precision in treatment. The multi-room suites
incorporate diagnostic quality high-field MR, CT and angio modalities
accessed effortlessly in the operating room setting. VISIUS Surgical
Theatres serve the neurosurgical, spinal, cardiovascular and
cerebrovascular markets and have been selected by 57 leading medical
institutions around the world.