Life Science Tools and Reagents: Global Markets
NEW YORK, June 8, 2011 /PRNewswire/ -- Reportlinker.com announces that a new market research report is available in its catalogue:
Life Science Tools and Reagents: Global Markets
The life science tools market has shown steady growth over the last couple of years despite the economic downturn. This market is currently valued at more than $42 billion and is projected to increase at compound annual growth rate (CAGR) of 13.6% to reach approximately $81 billion in 2016. Reagents and tools for DNA and RNA research are currently worth $27 billion and expected to increase at a 12.2% compound annual growth rate (CAGR) to reach $48 billion in 2016. Cell biology reagents represent at least 30% of the life science research tools market. This particular segment is currently estimated at $10 billion and predicted to at least double its value in the next 5 years to reach $24 billion, a 19.1% compound annual growth rate (CAGR).
INTRODUCTION
STUDY GOALS AND OBJECTIVES
This BCC Research report, Life Science Tools and Reagents: Global Markets, provides an overview of the current overall state of the life science tools and reagents industry, existing products on the market, and a detailed analysis of the competitive environments, including new potential markets for novel products and assay development. This study includes information about significant players, trends, and obstacles and other information affecting the market for research tools and reagents in the life science sector.
REASONS FOR DOING THIS STUDY
Reagents and research tools used in the life sciences are essential parts of routine laboratory research. The discovery of the PCR (polymerase chain reaction) is one of the best examples where a technical method opened a new era of molecular biology, and its significance was acknowledged with a Nobel Prize in 1993.
Yet, despite such contributions and its importance in biomedical research, potential investors often overlook the life science tools industry. It is important to understand that this market follows different business models as compared to the pharmaceutical industry. While pharmaceuticals need more financial leverage and time to develop successful drugs, reagent development is less risky. Reagents companies develop various strategies to grow and expand their activities, offering new outlooks on biotechnology and pharmaceutical market development. In addition, scientific trends, government policies, and the economy in general affect this industrial market differently as compared to pharmaceutical and drug discovery ventures. For example, the launch of new reagents or products is not affected by strict FDA guidelines.
This report highlights the main segments of the life science tools and reagents industry and its major market participants, including current and future market trends. Drivers and challenges in each segment of this industry will be discussed in detail, including forecasts for the next 5 years.
SCOPE OF REPORT
This report is essentially a business tool that can help market players evaluate new commercial opportunities in the life science tools and reagents market. The geographic scope of this study is global. This market is complex and consists of many different segments, each of which is affected differently by scientific and technological developments. This report identifies the main positive and negative factors affecting each segment, and forecasts market growth, future trends, and product and assay development in every major segment of this market.
METHODOLOGY AND INFORMATION SOURCES
Both primary and secondary research methodologies were used in preparing this study. Initially, a comprehensive and exhaustive search of the literature on drug discovery and already marketed products was conducted. These secondary sources included drug discovery and science-related journals, textbooks, press releases, marketing literature, other product/promotional literature, annual reports, security analyst reports, and other publications. A patent search and analysis were also conducted.9
In a second phase, a series of semi-structured interviews was conducted with company representatives, bench scientists, marketing representatives, and other personnel at biotechnology and pharmaceutical companies. Other sources included academics, technology, and consulting companies. Subsequent analysis of the documents and interviews notes was iterative.
CHAPTER ONE: INTRODUCTION
STUDY GOALS AND OBJECTIVES
REASONS FOR DOING THIS STUDY
SCOPE OF REPORT
METHODOLOGY AND INFORMATION SOURCES
INTENDED AUDIENCE
ANALYST CREDENTIALS
RELATED REPORTS
BCC ONLINE SERVICES
DISCLAIMER
CHAPTER TWO: SUMMARY
SUMMARY
SUMMARY TABLE GLOBAL MARKET FOR COMMON REAGENTS AND PRODUCTS IN THE LIFE SCIENCE TOOLS INDUSTRY BY SEGMENT, THROUGH 2016 ($ BILLIONS)
SUMMARY FIGURE GLOBAL MARKET FOR COMMON REAGENTS AND PRODUCTS IN THE LIFE SCIENCE TOOLS INDUSTRY BY SEGMENT, 2010-2016 ($ BILLIONS)
CHAPTER THREE: OVERVIEW
OVERVIEW
TABLE 1 GLOBAL LIFE SCIENCE TOOLS MARKET, THROUGH 2016 ($ BILLIONS)
FIGURE 1 GLOBAL LIFE SCIENCE TOOLS MARKET, 2008-2016 ($ BILLIONS)
FIGURE 2 INTEGRATION SCHEME BETWEEN DIFFERENT SCIENTIFIC AREAS OF RESEARCH
MAIN MARKET PARTICIPANTS IN THE LIFE SCIENCE TOOLS INDUSTRY
TABLE 2 GLOBAL MARKET SHARES OF THE LIFE SCIENCE RESEARCH TOOLS INDUSTRY BY SEGMENT, 2011 (%)
MERGERS AND ACQUISITIONS
TABLE 3 REPRESENTATIVE ACQUISITIONS IN THE LIFE SCINCE TOOLS INDUSTRY, 2010-2011 ($ BILLIONS)
GEOGRAPHIC DISTRIBUTION OF THE RESEARCH TOOLS INDUSTRY
TABLE 4 GLOBAL MARKET SHARES OF THE LIFE SCIENCE TOOLS INDUSTRY BY GEOGRAPHIC REGION, 2011 (%)
FIGURE 3 GLOBAL MARKET SHARES OF THE LIFE SCIENCE TOOLS INDUSTRY BY GEOGRAPHIC REGION, 2011 (%)
TECHNOLOGY PATENTS IN THE LIFE SCIENCE TOOLS INDUSTRY
MAJOR DRIVERS IN THE LIFE SCIENCE RESEARCH TOOLS INDUSTRY
BIOMARKER/DIAGNOSTIC INDUSTRIES
PERSONALIZED MEDICINE TREND
INNOVATIVE TECHNOLOGIES AND TRENDS
GOVERNMENT POLICIES AND FUNDING
CHAPTER FOUR: MOLECULAR BIOLOGY AND GENOMICS RESEARCH TOOLS
OVERVIEW
GENOMICS STUDIES AS A MARKET FOR LIFE SCIENCE TOOLS
TABLE 5 GLOBAL MARKET FOR GENOMICS PRODUCTS, THROUGH 2016 ($ BILLIONS)
MOLECULAR BIOLOGY TOOLS MARKET
DNA RESEARCH TOOLS
DNA Extraction/Purification Market
DNA Amplification and Polymerase Chain Reaction
TABLE 6 GLOBAL DNA AMPLIFICATION/PCR MARKET, THROUGH 2016 ($ BILLIONS)
TABLE 7 GLOBAL PCR MARKET SHARES BY COMPANY, 2011 (%)
TABLE 8 GLOBAL PCR MARKET SHARES BY GEOGRAPHIC REGION, 2011 (%)
DNA Microarrays
TABLE 9 GLOBAL MARKET FOR DNA MICROARRAYS, THROUGH 2016 ($ BILLIONS)
Sequencing in the Research Tools Market
TABLE 10 GLOBAL MARKET FOR DNA SEQUENCING, THROUGH 2016 ($ BILLIONS)
TABLE 11 GLOBAL MARKET FOR NGS AND GENERAL SEQUENCING, THROUGH 2016 ($ BILLIONS)
TABLE 12 MAIN MARKET PARTICIPANTS IN THE NGS MARKET AND RELATED USER STATISTICS, 2010 (%)
DNA Research-Related Products
LIFE SCIENCE TOOLS FOR RNA RESEARCH
RNA Purification
TABLE 13 GLOBAL MARKET SHARES OF RNA ISOLATION PRODUCTS BY COMPANY, 2011 (%)
TABLE 14 SELECT NEW PRODUCTS IN RNA RESEARCH
RNA Synthesis, Degradation, and Modification Products
TABLE 15 SELECT RNA SYNTHESIS, DEGRADATION, AND MODIFICATION PRODUCTS
RNA Interference
TABLE 16 GLOBAL RNA INTERFERENCE MARKET, THROUGH 2016 ($ MILLIONS)
Market Participants in RNA Interference
TABLE 17 GLOBAL RNA INTERFERENCE MARKET SHARES BY GEOGRAPHIC REGION, 2011 (%)
miRNA as a New Trend in Research Tools Development
SYNTHETIC BIOLOGY AS A NEW VENUE IN THE LIFE SCIENCE TOOLS INDUSTRY
CHAPTER FIVE: PROTEOMICS RESEARCH AS A MARKET FOR LIFE SCIENCE TOOLS AND REAGENTS
OVERVIEW
TABLE 18 GLOBAL MARKET FOR PROTEOMICS TOOLS, THROUGH 2016 ($ BILLIONS)
PROTEIN EXPRESSION TECHNIQUES
OVERVIEW
TABLE 19 PERCENTAGE USE OF SPECIFIC PROTEIN EXPRESSION TECHNIQUES (%)
PROKARYOTIC EXPRESSION SYSTEMS
MAMMALIAN EXPRESSION SYSTEMS
PROTEIN EXPRESSION IN INSECT CELL SYSTEMS
PROTEIN EXPRESSION IN YEAST CELL SYSTEMS
PROTEIN EXPRESSION IN PLANT CELL SYSTEMS
CELL-FREE SYSTEMS
TABLE 20 COMPARISON OF PROTEIN EXPRESSION SYSTEMS USED BY THE SCIENTIFIC COMMUNITY
PROTEIN EXPRESSION MARKET PARTICIPANTS
TABLE 21 PROTEIN EXPRESSION PROVIDER MARKET SHARES, 2011 (%)
PROTEIN PURIFICATION MARKET
OVERVIEW
EXTRACTION PROCEDURE
PRECIPITATION AND DIFFERENTIAL SOLUBILIZATION
CHROMATOGRAPHIC METHODS
Size Exclusion Chromatography
Separation Based on Charge or Hydrophobicity
Affinity Chromatography
Immunoaffinity Chromatography
High-Performance Liquid Chromatography
TABLE 22 GLOBAL MARKET FOR PROTEIN CHROMATOGRAPHY, THROUGH 2016 ($ MILLIONS)
TABLE 23 AVERAGE SPENDING PER SCIENTIST ON PURIFICATION/SEPARATION PRODUCTS, 2011 ($)
PROTEIN IDENTIFICATION AND CHARACTERIZATION TECHNIQUES
Mass Spectrometry
TABLE 24 GLOBAL MARKET FOR MASS SPECTROMETRY, THROUGH 2016 ($ MILLIONS)
Protein Sequencing Approach
ICAT (Isotope Coded Affinity Tags)
MudPit (Multi-dimensional Protein Identification Technology)
X-ray Crystallography
NMR (Nuclear Magnetic Resonance)
TABLE 25 PERCENTAGE OF TOTAL NMR APPLICATIONS IN VARIOUS SECTORS (%)
OTHER PRODUCTS AND RESEARCH TOOLS IN PROTEOMICS STUDIES
Two-Dimensional Gel Electrophoresis
TABLE 26 GLOBAL MARKET FOR 2D GEL ANALYSIS, THROUGH 2016 ($ MILLIONS)
Protein-Protein Interaction Identification Techniques
Protein Microarrays
TABLE 27 GLOBAL PROTEIN CHIP MARKET, THROUGH 2016 ($ MILLIONS)
Bioinformatics Tools for Proteomics
NEW PRODUCTS AND DEVELOPMENT TRENDS
MARKET PARTICIPANTS IN PROTEOMICS RESEARCH TOOLS
TABLE 28 PROTEOMICS MARKET PARTICIPANTS BY INDUSTRY SEGMENT
CHAPTER SIX: RECOMBINANT PROTEINS MARKET
OVERVIEW
NON-ENZYME RECOMBINANT PROTEINS
TABLE 29 GLOBAL MARKET FOR CYTOKINES AND GROWTH FACTORS, THROUGH 2016 ($ MILLIONS)
TABLE 30 GLOBAL MARKET SHARES OF CYTOKINES AND GROWTH FACTORS BY COMPANY, 2011 (%)
RECOMBINANT PROTEINS ENZYME MARKET
TABLE 31 GLOBAL MARKET SHARES OF RESEARCH TOOLS BY ENZYME CATEGORY, 2011 VS. 2016 (%)
KINASES
PHOSPHATASES
PHOSPHODIESTERASES (PDES)
EPIGENETIC ENZYMES
UPS ENZYMES: UBIQUITIN LIGASES, DEUBIQUITINASES, AND OTHERS
MARKET PARTICIPANTS AND END-USER ANALYSIS
TABLE 32 GLOBAL RECOMBINANT ENZYME MARKET SHARES BY CUSTOMER, 2011 (%)
IN VITRO ASSAY DEVELOPMENT MARKET
TABLE 33 SELECT IN VITRO ASSAY AND COMMERCIAL KIT PROVIDERS
CHAPTER SEVEN: ANTIBODIES AS LIFE SCIENCE TOOLS AND REAGENTS
OVERVIEW
POLYCLONAL ANTIBODIES (PABS)
MONOCLONAL ANTIBODIES
RECOMBINANT ANTIBODY PRODUCTION
ANTIBODY MARKET
TABLE 34 GLOBAL MARKET FOR ANTIBODIES BY INDUSTRY SEGMENT, THROUGH 2016 ($ BILLIONS)
TABLE 35 DISTRIBUTION OF VARIOUS APPLICATIONS FOR ANTIBODIES AS A RESEARCH TOOL, 2011 (%)
MARKET PARTICIPANTS
TABLE 36 MARKET SHARES OF CATALOG ANTIBODY PROVIDERS, 2011 (%)
TABLE 37 STATISTICS FOR ANTIBODY SOURCES (%)
TABLE 38 GLOBAL MARKET SHARES OF ANTIBODY PRODUCTION BY GEOGRAPHIC REGION, 2011 (%)
MARKET FOR LABELING AND PROBES
TYPES OF LABELING
Fluorescent Labeling
Chemiluminescent Labeling
Radioactive Labeling
TABLE 39 GLOBAL MARKET FOR VARIOUS LABELING AND PROBES, 2011 ($ BILLIONS)
CHAPTER EIGHT: CELL BIOLOGY REAGENTS MARKET
OVERVIEW
TABLE 40 GLOBAL MARKET FOR CELL BIOLOGY REAGENTS, THROUGH 2016 ($ BILLIONS)
TABLE 41 GLOBAL MARKET SHARES OF CELL BIOLOGY REAGENTS BY PRODUCT CATEGORY, 2011 (%)
MEDIUM/SERUM/SUPPLEMENTS
TRANSFECTION SYSTEMS
CELL LINES
FLOW CYTOMETRY MARKET
TABLE 42 GLOBAL MARKET FOR FLOW CYTOMETRY, THROUGH 2016 ($ BILLIONS)
CELL BIOLOGY MARKET PARTICIPANTS
TABLE 43 GLOBAL MARKET SHARES OF CELL BIOLOGY SUPPLIERS, 2011 (%)
CELL-BASED ASSAYS MARKET
TABLE 44 GLOBAL SHARES OF THE CELL-BASED ASSAYS MARKET, BY CATEGORY, 2011 (%)
GPCRS AS A TARGET FOR CELL-BASED ASSAY DEVELOPMENT
ION CHANNELS AS TARGETS FOR CELL-BASED ASSAY DEVELOPMENT
CELL-BASED KINASE ASSAYS
TABLE 45 GLOBAL MARKET FOR CELL-BASED ASSAYS, THROUGH 2016 ($ MILLIONS)
TABLE 46 GLOBAL CELL-BASED ASSAY MARKET BY GEOGRAPHIC REGION, 2011 (%)
CHAPTER NINE: LABORATORY ANIMALS SEGMENT IN THE LIFE SCIENCE RESEARCH TOOLS INDUSTRY
OVERVIEW
MARKET PARTICIPANTS
TABLE 47 SELECT COMPANIES SUPPLYING LABORATORY
ANIMALS FOR LIFE SCIENCE RESEARCH
CHAPTER TEN: IMAGING AND MICROSCOPY AS LIFE SCIENCE
RESEARCH TOOLS
OVERVIEW
IMAGING AND MICROSCOPY MARKET SEGMENTS
LIGHT MICROSCOPY
FLUORESCENT MICROSCOPY
CONFOCAL MICROSCOPY
ELECTRON MICROSCOPY
MARKET EVALUATION OF IMAGING AND MICROSCOPY
TABLE 48 GLOBAL IMAGING AND MICROSCOPY MARKET BY SEGMENT, 2010 ($ BILLIONS)
MARKET PARTICIPANTS
TABLE 49 SELECT IMAGING AND MICROSCOPY TOOLS PROVIDERS
CHAPTER ELEVEN: BIOINFORMATICS PRODUCTS AS PART OF LIFE SCIENCE TOOLS INDUSTRY
OVERVIEW
MARKET EVALUATION OF BIOINFORMATICS PRODUCTS
TABLE 50 GLOBAL BIOINFORMATICS MARKET, THJROUGH 2016 ($ BILLIONS)
CATEGORIES OF BIOINFORMATICS PRODUCTS
Hardware, Instruments, and Software Development
Database and Content Products and Services
Data Management and Storage
MARKET PARTICIPANTS
TABLE 51 GLOBAL BIOINFORMATICS MARKET BY GEOGRAPHIC REGION, 2011 (%)
CHAPTER TWELVE: METABOLOMICS AS A RESEARCH TOOLS MARKET OPPORTUNITY
OVERVIEW
TECHNIQUES AND METHODS FOR METABOLITE PROFILING
METABOLOMICS APPLICATIONS
MARKET EVALUATION OF METABOLITE PROFILING
TABLE 52 U.S. METABOLITE PROFILING MARKET, 2011-2016 ($ MILLIONS)
BIOMARKER DISCOVERY SERVICES
FURTHER DEVELOPMENT OF BIOINFORMATICS AND CHEMOMETRICS STUDIES
NEW TECHNOLOGICAL PLATFORMS
MARKET PARTICIPANTS
TABLE 53 SELECT MARKET PARTICIPANTS IN THE METABOLOMICS MARKET
CHAPTER THIRTEEN: NEW SCIENTIFIC TRENDS AS MARKETS FOR RESEARCH TOOLS DEVELOPMENT PRODUCTS
EPIGENETICS AND ITS RESEARCH TOOLS
OVERVIEW
TABLE 54 GLOBAL MARKET FOR DRUG DISCOVERY IN EPIGENETIC RESEARCH, THROUGH 2016 ($ BILLIONS)
EPIGENETIC RESEARCH TOOLS AND PRODUCTS
DNA Methylation
Histone Methylations and Modifications
TABLE 55 PERCENTAGE OF COMMERCIAL KITS GENERALLY PURCHASED FOR EPIGENETIC RESEARCH (%)
TABLE 56 SELECT SUPPLIERS OF EPIGENETIC PRODUCTS
MARKET FOR EPIGENETICS TOOLS
TABLE 57 GLOBAL MARKET RESEARCH TOOLS IN THE EPIGENETIC SEGMENT, THROUGH 2016 ($ BILLIONS)
STEM CELL RESEARCH TOOLS
OVERVIEW
TABLE 58 GLOBAL MARKET FOR STEM CELL RESEARCH AND DRUG DISCOVERY, THROUGH 2016 ($ BILLIONS)
RESEARCH TOOLS AND PRODUCTS FOR STEM CELL RESEARCH
TABLE 59 U.S. MARKET FOR STEM CELL RESEARCH TOOLS, THROUGH 2016 ($ BILLIONS)
TABLE 60 PERCENTAGE OF SPENDING ON VARIOUS PRODUCT CATEGORIES IN STEM CELL RESEARCH, 2011 VS. 2016 (%)
TABLE 61 DISTRIBUTION OF STEM CELL RESEARCH TOOL PURCHASES BY CUSTOMER, 2010 (%)
TABLE 62 CATEGORIES OF STEM CELL RESEARCH THAT REQUIRE DEVELOPMENT OF SPECIFIC RESEARCH TOOLS
TABLE 63 GLOBAL STEM CELL RESEARCH MARKET OPPORTUNITIES BY GEOGRAPHIC REGION, 2010 (%)
LEADING STEM CELL REAGENT COMPANIES
TABLE 64 SELECT REAGENT PROVIDERS IN STEM CELL RESEARCH
UBIQUITIN-PROTEASOME RESEARCH AS A MARKET FOR LIFE SCIENCE TOOL DEVELOPMENT
OVERVIEW
TABLE 65 ENZYMATIC COMPONENTS OF THE UBIQTUINATIONDEUBIQUITINATION REACTION
ASSAY DEVELOPMENT AND REAGENTS FOR UPS DRUG DISCOVERY
BOSTON BIOCHEM
ENZO LIFE SCIENCES
LIFE TECHNOLOGIES
LIFESENSORS
MESO SCALE DISCOVERY
PROTEASOMES.COM
TABLE 66 EXAMPLES OF COMMON UPS REAGENT PRICES BY COMPANY ($)
ASSAY DEVELOPMENT FOR UPS DRUG DISCOVERY
TABLE 67 PROVIDERS OF SCREENING ASSAY TOOLS
LANTHASCREEN TECHNOLOGY FOR UBIQUITINATIONDECONJUGATION ASSAYS
ALPHASCREEN APPROACH FOR UBIQUITINATIONDECONJUGATION ASSAYS
CISBIO
MESO SCALE DISCOVERY
LIFESENSORS
PROMEGA
MILTENYI BIOTEC
BIOGENOVA
UBIQUIGENT
UBIQUITIN AS A RESEARCH TOOL FOR OTHER DRUG DISCOVERIES VENUES
SCIL PROTEINS
DUALSYSTEM BIOTECH
CHAPTER FOURTEEN: MARKET SUMMARY
TABLE 68 GLOBAL LIFE SCIENCE TOOLS MARKET BY SEGMENT, THROUGH 2016 ($ BILLIONS)
TABLE 69 FINALISTS AND WINNERS OF THE LIFE SCIENCE INDUSTRY AWARDS, 2008
TABLE 70 MAIN MARKET PARTICIPANTS IN THE LIFE SCIENCE TOOLS INDUSTRY
CHAPTER FIFTEEN: PROFILES OF SELECT COMPANIES
LIFE TECHNOLOGIES CORP.
PROMEGA CORP.
SIGMA-ALDRICH CORP.
THERMO FISHER SCIENTIFIC, INC.
WATERS CORP.
APPENDIX
LIST OF COMPANIES
ABGENT, INC.
ACTIVE MOTIF
AFFYMETRIX
AGILENT TECHNOLOGIES
ALDEVRON
ALPHAHELIX MOLECULAR DIAGNOSTICS AB
AMPLICON EXPRESS
ANASPEC (EUROGENTEC GROUP)
APERIO TECHNOLOGIES, INC.
APPLIED PRECISION, INC.
APPLIED SPECTRAL IMAGING, INC.
ATACTIC TECHNOLOGIES
AVANTI POLAR LIPIDS, INC.
AVIVA BIOSCIENCES CORP.
BD BIOSCIENCES
BECKMAN COULTER, INC.
BENITEC
BIO-RAD LABORATORIES
BIOSYNTHESIS, INC.
BIOCARTA, LLC
BIOLIFE SOLUTIONS, INC.
BIOLOG
BIOMYX TECHNOLOGY
BIONEER
BIOVISION
BRUKER CORP.
CALIPER LIFE SCIENCES
CELL BIOSCIENCES, INC.
CELL SCIENCES
CELL SIGNALING TECHNOLOGY
CEPHEID
CHARLES RIVER LABORATORIES INTERNATIONAL, INC.
CHEMGENES CORP.
COMPLETE GENOMICS, INC.
CORNING, INC.
DNA2.0
DNAPRINT GENOMICS
DYOMICS GMBH
ECHELON BIOSCIENCES, INC.
EMD4BIOSCIENCES
ENZO BIOCHEM
GE HEALTHCARE U.K., LTD.
GENECRAFT
GENETEX, INC.
GENOME EXPLORATIONS
GENOWAY
GLYCOTECH
F. HOFFMAN-LA ROCHE AG
ILLUMINA, INC.
INTEGRATED DNA TECHNOLOGIES, INC.
IRVINE SCIENTIFIC
KREATECH DIAGNOSTICS
LI-COR
LIFESENSORS, INC.
LIFE TECHNOLOGIES CORP.
LONZA GROUP
MILLIPORE (EMD GROUP)
MOLECULAR DEVICES, INC.
NEW BRUNSWICK SCIENTIFIC
ORIGENE TECHNOLOGIES
PERKIN-ELMER
PROMEGA CORP.
PROSCI, INC.
PROTAGEN AG
PROTEA BIOSCIENCES, INC.
QIAGEN
R&D SYSTEMS, INC.
SHIMADZU CORP.
SIGMA-ALDRICH
STEMCELL TECHNOLOGIES, INC.
STEMGENT
THERMO FISHER SCIENTIFIC, INC.
TRILINK BIOTECHNOLOGIES
TOCRIS BIOSCIENCE
UBIQUIGENT
VITRO DIAGNOSTICS, INC.
WATERS CORP.
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