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Lilly and Incyte Announce Webcast to Discuss Baricitinib Phase III Data

Eli Lilly and Company logo.

News provided by

Eli Lilly and Company

May 28, 2015, 01:00 ET

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INDIANAPOLIS, May 28, 2015  /PRNewswire/ -- Eli Lilly and Company (NYSE: LLY) and Incyte Corporation (Nasdaq: INCY) will host a webcast on June 11 to discuss data from the first two pivotal Phase III studies of baricitinib in rheumatoid arthritis. Data from these two trials, RA-BEACON and RA-BUILD, will be presented on June 11 during the Scientific Programme for the EULAR Congress 2015 in Rome, Italy.

Incyte logo.

The webcast will be held from 10:00 to11:00 a.m. Eastern Daylight Time. The live audio webcast can be accessed through a link that will be posted on the investor sections of Lilly's and Incyte's websites. In addition, the webcast will be available for replay through June 18, 2015.

About Baricitinib

Baricitinib is a once daily, oral, selective JAK1 and JAK2 inhibitor. There are four known JAK enzymes: JAK1, JAK2, JAK3 and TYK2. JAK-dependent cytokines have been implicated in the pathogenesis of a number of inflammatory and autoimmune diseases, suggesting that JAK inhibitors may be useful for the treatment of a broad range of inflammatory conditions. Baricitinib demonstrates approximately 100-fold greater potency of inhibition against JAK1 and JAK2 than JAK 3 in kinase assays.

In December 2009, Lilly and Incyte announced an exclusive worldwide license and collaboration agreement for the development and commercialization of baricitinib and certain follow-on compounds for patients with inflammatory and autoimmune diseases. Baricitinib is currently in Phase III clinical development for rheumatoid arthritis and Phase II development for psoriasis and diabetic nephropathy.

About Baricitinib Phase III Trials

Lilly and Incyte are conducting four pivotal Phase III clinical trials of baricitinib in patients with moderately-to-severely active rheumatoid arthritis to support regulatory submission in most countries. An additional Phase III study was initiated to support clinical development in China. The clinical trial program includes a wide range of patients including those who are methotrexate naïve, inadequate responders to methotrexate, inadequate responders to conventional disease-modifying anti-rheumatic drugs, or inadequate responders to TNF inhibitors. Four of these five pivotal studies are expected to be completed by the end of 2015. Patients completing any of the five Phase III studies can enroll in a long-term extension study. For additional information on this clinical trial program, please visit www.clinicaltrials.gov.

About Incyte

Incyte Corporation is a Wilmington, Delaware-based biopharmaceutical company focused on the discovery, development and commercialization of proprietary therapeutics for oncology and inflammation. For additional information on Incyte, please visit the Company's web site at www.incyte.com.

About Eli Lilly and Company

Lilly is a global healthcare leader that unites caring with discovery to make life better for people around the world. We were founded more than a century ago by a man committed to creating high-quality medicines that meet real needs, and today we remain true to that mission in all our work. Across the globe, Lilly employees work to discover and bring life-changing medicines to those who need them, improve the understanding and management of disease, and give back to communities through philanthropy and volunteerism. To learn more about Lilly, please visit us at www.lilly.com and newsroom.lilly.com/social-channels. (P-LLY)

This press release contains forward-looking statements about baricitinib as a potential treatment for patients with rheumatoid arthritis and reflects Lilly and Incyte's current beliefs. However, as with any pharmaceutical product, there are substantial risks and uncertainties in the process of development and commercialization. There is no guarantee that future study results will be consistent with study findings to-date, or that baricitinib will receive regulatory approval. For further discussion of these and other risks and uncertainties, see Lilly's and Incyte's filings with the United States Securities and Exchange Commission. Lilly and Incyte undertake no duty to update forward-looking statements.

Refer to: 

Celeste Stanley; [email protected]; 317-626-8896 (Lilly media)


Phil Johnson; [email protected]; 317-655-6874 (Lilly investors)


Michael Booth, DPhil; [email protected]; 302-498-5914 (Incyte)

Photo - http://photos.prnewswire.com/prnh/20031219/LLYLOGO
Photo - http://photos.prnewswire.com/prnh/20120608/DE21226LOGO

SOURCE Eli Lilly and Company

Related Links

http://www.lilly.com

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