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MitoSense Inc. und die Universität Uppsala geben in Zusammenarbeit mit dem Elliott Mitochondrial Center und der Sallie Astor Burdine Breast Foundation einen Durchbruch bei der Erhaltung von Mitochondrien bekannt
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Jan 25, 2024, 08:30 ET

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PLYMOUTH, Massachusetts, 25. Januar 2024 /PRNewswire/ -- MitoSense Inc., ein führender Innovator in der Biotechnologie mit Schwerpunkt auf neurodegenerativen Erkrankungen, gibt in Zusammenarbeit mit der Universität Uppsala, dem Elliott Mitochondrial Center und der Sallie Astor Burdine Breast Foundation in Baton Rouge, Louisiana, USA, einen bahnbrechenden wissenschaftlichen Durchbruch auf dem Gebiet der mitochondrialen Konservierung bekannt, einem Schlüsselelement bei mitochondrialen Transplantationstherapien.

Die Studie „Extracellular Vesicles from Mesenchymal Stromal Cells (imEVs) Enhance Cold Preservation of Isolated Mitochondria" (Extrazelluläre Vesikel aus mesenchymalen Stromazellen (imEVs) verbessern die Kältekonservierung isolierter Mitochondrien) zeigt eine innovative Technik zur Erhaltung der Lebensfähigkeit isolierter Mitochondrien während der Kühllagerung.  Diese Methode, bei der extrazelluläre Vesikel aus mesenchymalen Stromazellen (imEVs) verwendet werden, stellt einen bedeutenden Fortschritt in der Mitochondrienmedizin dar. Die Transplantation mitochondrialer Organellen (MOT™) ist eine innovative Strategie zur Behandlung mitochondrialer Dysfunktionen, wie z. B. bei neurodegenerativen Erkrankungen wie Verletzungen, Parkinson, amyotropher Lateralsklerose (ALS) und Alzheimer-Krankheit. Eine der Herausforderungen für eine breite Anwendung ist jedoch eine Methodik zur Konservierung isolierter Mitochondrien.

Karl-Henrik Grinnemo und Sergey Rodin von der Universität Uppsala, die maßgeblich an dieser Forschung beteiligt waren, bezeichneten die Studie als „Meilenstein der Mitochondrienforschung". Sie wiesen auf die bedeutenden Auswirkungen dieser Entdeckung hin, die neue therapeutische Wege für Erkrankungen im Zusammenhang mit mitochondrialer Dysfunktion eröffnen.

Van Hipp, Vorsitzender von MitoSense, betonte die Bedeutung der Zusammenarbeit bei der Erzielung dieses Durchbruchs. „Die Partnerschaft mit dem Elliott Mitochondrial Center und der Sallie Astor Burdine Breast Foundation hat maßgeblich zu dieser Entdeckung beigetragen und spiegelt unser gemeinsames Engagement für bahnbrechende medizinische Lösungen wider", erklärte er.

MitoSense Inc. ist ein Vorreiter bei der Entwicklung neuartiger Therapien für neurodegenerative Erkrankungen. Seine patentierte MOT™-Technologie hat vielversprechende Ergebnisse bei der Behandlung mitochondrialer Dysfunktion gezeigt. Diese Technologie wird derzeit in einem von CAMP/Vinnova geförderten Projekt (https://atmpsweden.se/) untersucht, das sich mit Ischämie-Reperfusionsschäden nach Herzinfarkt befasst.

Diese Zusammenarbeit stellt eine wichtige Ergänzung zu den Erfolgen von MitoSense Inc. dar und unterstreicht die entscheidende Rolle des Unternehmens bei der Förderung der medizinischen Wissenschaft und der Verbesserung der Patientenversorgung.

Informationen zu MitoSense Inc.: MitoSense Inc. steht an der Spitze der Biotechnologie und widmet sich der Entwicklung innovativer Therapien für neurodegenerative Erkrankungen. Das Engagement des Unternehmens für die Förderung der mitochondrialen Gesundheit zeigt sich in der laufenden Forschung und der Erkundung neuer Behandlungsmöglichkeiten.

https://www.mitosenseinc.com/

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