NEB Releases CutSmart™ Buffer and Sets New Standard for Restriction Enzyme Convenience and Performance

Apr 22, 2013, 13:40 ET from New England Biolabs

IPSWICH, Mass., April 22, 2013 /PRNewswire/ -- New England Biolabs (NEB), a leader in the production of reagents for the life science industry, announces the release of CutSmart Buffer. This latest development from NEB supports an industry-leading portfolio of over 200 restriction enzymes that exhibit 100% activity in a single buffer. With CutSmart Buffer, it is significantly easier to set up DNA digestion experiments, including double digest reactions. Since CutSmart Buffer includes BSA, there are fewer tubes and pipetting steps to worry about. Additionally, many DNA modifying enzymes are 100% active in CutSmart Buffer, eliminating the need for subsequent downstream purification.

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Simultaneously with the release of this new buffer, NEB instituted stricter criteria for its Time-Saver qualified restriction enzymes. These enzymes have been demonstrated to digest DNA fast, in as little as 5 to 15 minutes. However, they have also been shown to produce the same results in overnight incubations, should such scheduling flexibility be necessary. This type of qualification, which is unique to NEB, is available for more than 180 of NEB's enzymes.

"The combination of CutSmart Buffer and a more stringent definition of the Time-Saver qualification sets a new industry standard for convenience and performance, when using restriction enzymes," says Penny Devoe, Product Marketing Manager at NEB. "Together with our engineered High-Fidelity (HF) Restriction Enzymes, RE-Mix® Restriction Enzyme Master Mixes, and the largest selection (276) of specificities, we are confident that NEB can support every scientists' restriction enzyme needs."

As NEB transitions its restriction enzyme portfolio to this new buffer system, it will continue to support customers using the old buffer system. This includes maintaining supplies of the old buffers and by making the technical support information for both systems, old and new, available on

CutSmart Buffer is being launched at Experimental Biology 2013, which is being held in Boston, MA on April 20-24th. For more information on CutSmart Buffer, visit:

About New England Biolabs
Established in the mid 1970's, New England Biolabs, Inc. is the industry leader in the discovery and production of enzymes for molecular biology applications and now offers the largest selection of recombinant and native enzymes for genomic research. NEB continues to expand its product offerings into areas related to PCR, gene expression, library preparation for next generation sequencing, cellular analysis, epigenetics and RNA analysis. Additionally, NEB is focused on strengthening alliances that enable new technologies to reach key market sectors. New England Biolabs is a privately held company, headquartered in Ipswich, MA, and has extensive worldwide distribution through a network of exclusive distributors, agents and seven subsidiaries located in Canada, China, France, Germany, Japan, Singapore and the UK. For more information about New England Biolabs visit

RE-MIX® is a registered trademark of New England Biolabs, Inc.
CUTSMART™, HF™ and TIME-SAVER™ are trademarks of New England Biolabs, Inc.


SOURCE New England Biolabs