NeuroCog Trials Captures Video Recordings of Neurocognitive Testing in a Multinational Clinical Trial

Reflects an evolution toward more 'noise-cancelling' data monitoring methods to enhance signal detection

Nov 14, 2011, 09:42 ET from NeuroCog Trials, Inc.

DURHAM, N.C., Nov. 14, 2011 /PRNewswire/ -- NeuroCog Trials, Inc. and Advance Visuals, Inc. announced today that the use of video recordings of neurocognitive testing in a large international clinical trial is helping to identify both subtle and gross errors in test administration and scoring.  This video recording technology reflects an evolution towards greater vigilance regarding the accurate, unbiased assessment of neuropsychological effects of new drugs.

The use of video review is providing vivid data to enhance centralized data review of the neurocognitive testing that is occurring at sites around the world.  These data, in turn, are enabling near immediate remediation of errors, preventing them from reoccurring in future testing sessions.  Moreover, videotaping raters may also produce a 'sentinel' effect, whereby rater adherence to the assessment protocol is magnified.  This is critically important in large multisite trials where the ability to produce consistently high quality data across sites is often strained by geographic, economic, and cultural differences.

Richard Keefe, Ph.D., Founder and Chief Executive Officer, said, "This kind of heightened scrutiny of the administration of neuropsychological tests is helping to improve data accuracy, resulting in a more exacting test of the potential pro-cognitive effects of new drugs in clinical trials."  Charlie Burnham, Chief Executive Officer of Advance Visuals, NeuroCog Trials partner in this effort, added, "New technologies have allowed us to develop compact, web-based systems for recording and remotely reviewing clinical interviews.  These systems are secure, easy to use, and can be deployed in every country."

About NeuroCog Trials

NeuroCog Trials Inc. is the leading cognition services company for the pharmaceutical industry.  For more than 10 years, NeuroCog Trials has provided consulting, site screening, rater training and certification, and data review services to more than 50 clinical trials in over 25 countries.  NeuroCog Trials has certified more than 4,000 neurocognitive testers and assured data quality for over 50,000 assessments across a variety of therapeutic areas, including schizophrenia, Alzheimer's disease, major depressive disorder, bipolar disorder and brain cancer.  Our mission is to facilitate the development of novel therapies to enhance cognition.  We bring to all of our work deep expertise, strategic innovation, and an unwavering commitment to research excellence.

For more information on NeuroCog Trials, its services, and licensing inquiries for its exclusive neuropsychological and functional capacity assessment batteries, please see

About Advance Visuals

Advance Visuals has been a leader in custom video solutions for the healthcare industry since 1983.  It has produced hundreds of "gold standard" reference patient interviews for rater-training in over 25 languages.  Responding to the increased need for centralized rating and review, the company has developed a series of onsite video recording and upload kits for use in clinical trials.  In addition, the company provides extensive training and customized instruction materials for these systems so as to assist sites in creating clear, ratable records.  It maintains an international network of dedicated web servers and provides ongoing technical support for its systems.

For more information on Advance Visuals, please contact:

Michael Hufford, Ph.D.
(919) 401-4642
NeuroCog Trials, Inc.

Charlie Burnham
Advance Visuals, Inc.

SOURCE NeuroCog Trials, Inc.