DENVER, Oct. 21, 2015 /PRNewswire/ -- New studies conducted by the Colorado Center for Reproductive Medicine (CCRM) conclude that single embryo transfer (SET) with comprehensive chromosomal screening (CCS) is a successful and viable option for women age 35 and older undergoing in vitro fertilization (IVF) giving them success as high as their younger counterparts. Both studies will be presented at the American Society for Reproductive Medicine Annual Meeting in Baltimore, October 17-21, 2015.
In conjunction with CCS, SET is the most effective way of reducing multiple pregnancy rates associated with assisted reproductive technology. The single greatest health risk for women who conceive following fertility treatment is a multiple pregnancy (a pregnancy with two or more fetuses). These risks include miscarriage, pre-eclampsia, postpartum hemorrhage, maternal and/or fetal mortality, as well as very pre-term birth resulting in lengthy stays in neonatal intensive care and ongoing health consequences for premature infants.
CCRM researchers examined 1,000 single embryo transfers. All outcomes were comparable between younger women (<37 years) and women of advanced maternal age (38-42 years), including high pregnancy rates and live birth (AMA = 60.0 percent vs. <37 years = 64.6 percent), low miscarriage rates (AMA = 2.7 percent vs. <37 years = 4.3 percent), and healthy delivery outcomes. CCS allows AMA women to have success that's equal to their younger counterparts independent of their maternal age.
Concerns about maternal and perinatal morbidity associated with multiple births have led to attempts to restrict the number of embryos transferred. Some European and Asia/Pacific countries, such as Australia, New Zealand, Sweden, and the UK, already have SET policies in place to reduce the risk of women having fertility treatment bearing multiples.
CCRM is the first to investigate birth outcomes of singleton deliveries with CCS revealing no additional risk from the embryo biopsy to fetal growth and/or perinatal outcomes compared to non-CCS SETs.
"CCRM's ultimate goal is to help our patients accomplish a single embryo transfer resulting in one healthy baby born," says William Schoolcraft, M.D., founder and medical director of CCRM. "The bottom line is the health of the baby and the mom is most important."
Founded in 1987 by Dr. William Schoolcraft, the Colorado Center for Reproductive Medicine (CCRM) is one of the nation's leading infertility treatment centers, providing a wide spectrum of infertility treatments ranging from basic infertility care to advanced in vitro fertilization (IVF) technology. CCRM has locations in Colorado, Atlanta, Houston, Minneapolis, Orange County and Toronto, Canada. Dr. Schoolcraft and his colleagues achieve some of the highest pregnancy rates in the country. CCRM has been ranked "The #1 Fertility Center in the U.S. with the Greatest Chance of Success" by Child.com. To learn more, visit www.ccrmivf.com. Follow us on Facebook and Twitter.
Katie Trexler Kern, Evolution Communications Agency
303.941.4118 or [email protected]
Sarah Stavros, Colorado Center for Reproductive Medicine
303.761.0579 or [email protected]