Next Generation Sequencing (NGS) Market Poised to Hit $42.25 Billion by 2033: Key Drivers Behind the Surge - Latest Study by Grand View Research, Inc.

SAN FRANCISCO, Nov. 13, 2025 /PRNewswire/ -- The global next-generation sequencing market size is anticipated to reach USD 42.25 billion by 2033, growing at a CAGR of 18.0% from 2025 to 2033. The next-generation sequencing (NGS) market is experiencing significant growth, driven by the increasing demand for advanced genomic research, ongoing technological advancements in sequencing platforms, and, crucially, the rising adoption of NGS in clinical diagnostics. This technology revolutionizes disease diagnosis and monitoring by offering precise, rapid, and comprehensive genomic insights. Its clinical application is particularly notable in non-invasive prenatal testing (NIPT), which provides early and accurate detection of chromosomal abnormalities, and in extensive use for rare disease diagnosis, carrier screening, and oncology-based testing, where identifying genetic mutations is vital for targeted therapy and disease management.

Technological innovation stands as a significant driver propelling the next-generation sequencing (NGS) market growth, with continuous advancements in sequencing platforms, such as whole genome sequencing (WGS), whole exome sequencing (WES), and targeted sequencing, significantly enhancing the technology's accuracy, speed, and scalability. These innovations, which have reduced sequencing costs and turnaround times, are being complemented by the development of portable, automated, and high-throughput systems, including benchtop and nanopore-based platforms, making genomic analysis more accessible for decentralized testing. Furthermore, the integration of AI-driven bioinformatics tools and cloud-based data analysis platforms is simplifying complex data interpretation and enabling real-time, large-scale analysis, ultimately expanding the practical applications of NGS across research and clinical domains such as personalized medicine, epidemiology, and drug development, thus cementing technological advancement as a key market growth driver.

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The next-generation sequencing (NGS) market is propelled by a confluence of factors, starting with a high degree of technological innovation, which includes ongoing advances in single-cell, long-read sequencing, and AI-driven data analysis, exemplified by product launches like Roche's SBX sequencing technology with Xpandomer chemistry in February 2025, which enhances accuracy, speed, and clinical utility while reducing costs. This innovation is closely linked to product expansion, as companies continually launch new platforms, portable sequencers, and advanced bioinformatics tools to enhance workflow efficiency and meet diverse clinical and research needs. Furthermore, significant merger and acquisition (M&A) activity is fueling market growth and consolidation, allowing leading players to expand their technological capabilities and geographic reach; a notable example is Illumina's June 2025 agreement to acquire SomaLogic to improve its multi-omics capabilities. Crucial to broad adoption are regulatory frameworks which ensure the safety and efficacy of NGS-based assays, as increasing approvals from bodies like the FDA build confidence and facilitate integration into routine clinical practice. Finally, regional expansion into emerging markets across Asia-Pacific and Latin America is driving significant growth by leveraging improving healthcare infrastructure and government initiatives for genomic research, allowing companies to diversify their customer base and sustain long-term market growth worldwide.

Next Generation Sequencing Market Report Highlights:

• Based on product, the consumables segment held the largest market share in 2024 and is expected to grow at the fastest CAGR from 2025 to 2033.
• Based on technology, the targeted sequencing and resequencing segment held the largest revenue share of 48.46% in 2024.
• Based on application, the consumer genomics segment is projected to grow at the fastest CAGR over the forecast period.
• Based on workflow, the sequencing segment held the highest market share of 64.10% in 2024 and is expected to grow at the fastest rate over the forecast period.
• Based on end use, the clinical research segment is anticipated to be the fastest-growing segment during the forecast period.

Read full market research report on Next Generation Sequencing Market with TOC - Next Generation Sequencing Market Size, Share & Trends Analysis Report By Technology (Targeted Sequencing & Resequencing, WGS), By Product (Platform, Consumables), By Application, By Workflow, By End Use, By Region, And Segment Forecasts, 2025 - 2033

Next Generation Sequencing Market Segmentation

Grand View Research has segmented the next-generation sequencing market based on technology, product, workflow, end use, and region:

Next Generation Sequencing Market - Technology Outlook (Revenue, USD Million, 2021 - 2033)

• WGS
• Whole Exome Sequencing
• Targeted Sequencing & Resequencing
• DNA-based
• RNA-based
• Others

Next Generation Sequencing Market - Product Outlook (Revenue, USD Million, 2021 - 2033)

• Platform
• Sequencing
• Data Analysis
• Consumables
• Sample Preparation
• Target Enrichment
• Others

Next Generation Sequencing Market - Application Outlook (Revenue, USD Million, 2021 - 2033)

• Oncology
  • Diagnostics and Screening
    • Oncology Screening
      • Sporadic Cancer
      • Inherited Cancer
    • Companion Diagnostics
    • Other Diagnostics
  • Research Studies

• Clinical Investigation
  • Infectious Diseases
  • Inherited Diseases
  • Idiopathic Diseases
  • Non-Communicable/Other Diseases
• Reproductive Health
  • NIPT
    • Aneuploidy
    • Microdeletions

• PGT
• Newborn Genetic Screening
• Single Gene Analysis
• HLA Typing/Immune System Monitoring
• Metagenomics, Epidemiology & Drug Development
• Agrigenomics & Forensics
• Consumer Genomics

Next Generation Sequencing Market - Workflow Outlook (Revenue, USD Million, 2021 - 2033)

• Pre-Sequencing
• Nucleic Acid Extraction
• Library Preparation
• Sequencing
• NGS Data Analysis
• NGS Primary Data Analysis
• NGS Secondary Data Analysis
• NGS Tertiary Data Analysis

Next Generation Sequencing Market - End Use Outlook (Revenue, USD Million, 2021 - 2033)

• Academic Research
• Clinical Research
• Hospitals & Clinics
• Pharma & Biotech Entities
• Other Users

Next Generation Sequencing Market - Regional Outlook (Revenue, USD Million, 2021 - 2033)

• North America
• U.S.
• Canada
• Mexico
• Europe
• Germany
• UK
• France
• Italy
• Spain
• Denmark
• Sweden
• Norway
• Asia Pacific
• Japan
• China
• India
• South Korea
• Australia
• Thailand
• Latin America
• Brazil
• Argentina
• Middle East & Africa
• South Africa
• Saudi Arabia
• UAE
• Kuwait

List of Key Players in the Next Generation Sequencing Market

• Illumina
• F. Hoffman-La Roche Ltd.
• QIAGEN
• Thermo Fisher Scientific, Inc.
• Bio-Rad Laboratories, Inc.
• PacBio
• Oxford Nanopore Technologies
• Revvity, Inc.
• Merck KGaA
• BGI

Check out more related studies published by Grand View Research:

• Clinical Oncology Next Generation Sequencing Market  - The global clinical oncology next generation sequencing market size is anticipated to reach USD 1,930.2 million by 2033, according to a new report by Grand View Research, Inc. The market is projected to grow at a CAGR of 16.77% from 2025 to 2033. The clinical oncology next generation sequencing (NGS) market is in high demand. It is projected to expand at an increasing rate throughout the forecast period owing to the rising healthcare expenditure triggering the development of effective personalized medicine & therapeutic procedures for cancer and increasing adoption of NGS.
• Next-generation Sequencing Services Market  - The global next-generation sequencing services market size is expected to reach USD 40.43 billion by 2033, according to a new report by Grand View Research, Inc. It is expected to expand at a CAGR of 22.54% from 2025 to 2033. The development of next-generation sequencing (NGS) technologies has revolutionized gene sequencing in terms of reproducibility and cost savings. This has resulted in the introduction of several advancements in NGS technology to promote its usage in clinical labs and hospitals. Most current innovations in this field revolve around simplifying the usage of seq-technology and making it more sophisticated. These factors have driven the uptake of NGS services across various end-users.
• Next-generation Sequencing Library Preparation Market  - The global next-generation sequencing library preparation market size is anticipated to reach USD 5.33 billion by 2033, according to a new report by Grand View Research, Inc. The market is projected to grow at a CAGR of 13.3% from 2025 to 2033. Owing the to increasing prevalence of genetic diseases, decreasing costs of sequencing, and rising usage of NGS in disease diagnostics. Moreover, numerous market players offer a broad spectrum of solutions for NGS library preparation to suit the specific requirements of NGS-based analysis.
• Next-generation Sequencing Data Analysis Market  - The global next-generation sequencing data analysis market size is estimated to reach USD 3.45 billion by 2030, expanding at a CAGR of 23.10% from 2025 to 2030, according to a new report by Grand View Research, Inc. The growth can be attributed to a significant decline in the cost of NGS installation in clinical diagnosis. Furthermore, the accessibility of genomic and proteomic data is anticipated to create significant growth opportunities. In addition, a reduction in the cost of sequencing is anticipated to boost the adoption rate of NGS, which would further drive the industry.

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