NEW YORK, Aug. 25, 2017 /PRNewswire/ -- One Drop today announced the results of a retrospective study of people with diabetes (type 1 and type 2) using the One Drop | Mobile diabetes management app, demonstrating a 1.1% to 1.3% absolute reduction in A1C in just 4 months. The results were published yesterday, August 24, 2017, in JMIR Diabetes.
The One Drop | Mobile app for iOS and Android is available for free in the App Store or Google Play Store. With One Drop | Mobile, users can manually and passively (via Apple HealthKit, Google Fit, and the One Drop | Chrome blood glucose meter) store, track, and share data. Users can schedule medication reminders, view statistics, set goals, track A1c and weight, get data-driven insights, provide and receive encouragement from other users, and get tips and advice to assist with diabetes management.
Using retrospective app-collected data, One Drop in collaboration with U.S. and non-U.S.-based scientists, assessed the A1c change of people using One Drop | Mobile. They also assessed the relationship between tracking self-care with the app and changes in A1c.
"We used real-world data to produce timely and relevant results," said Dr. Chandra Osborn, Vice President of Health and Behavioral Informatics at One Drop. "More often than not, relevance and the gold standard randomized controlled trial are at odds. We didn't perform a RCT on outdated technology. We studied current technology and recent data, and found A1c improved among people using the One Drop app. We also linked that improvement to tracking self-care with the app." Dr. Osborn added, "From study to publication in less than 3 months is unheard of. That's impossible to do with a RCT. When it comes to technology, relevance and speed are everything."
As of June 7, 2017, 1288 people with type 1 or type 2 diabetes had entered two A1c values in the app (from 2 to 12 months apart), had their diabetes diagnoses verified with medications entered in the app, and had an average blood glucose consistent with their self-reported A1c values. Of the 367 people with type 1 diabetes and 921 people with type 2 diabetes, 35% were female, diagnosed with diabetes for a mean 9 years, and tracked an average 1700 self-care activities in the app between their two A1c values. Self-reported A1c can be as accurate as laboratory A1c , and we confirmed self-reported A1c was significantly associated with 90-day average blood glucose (rho=.73 to .75, P<.001) and consistent with cohort studies testing the relationship between blood glucose and laboratory A1c. During a median of 4 months, the following outcomes were observed :
A1c improved by -1.1% (from 8.3% to 7.2% in adjusted analyses, P<.001) across all users studied.
A1c improved by -1.3% (from 8.3% to 7.0%, P<.001) for users with T2D.
A1c improved by -0.9% (from 8.4% to 7.5%, P<.001) for users with T1D.
In unadjusted and adjusted analyses, using One Drop | Mobile to record food was associated with greater A1c improvement (all models, P<.05).
"Prior to this study, the scientific literature told us that diabetes mobile apps could potentially improve A1c by -0.45%," said Jeff Dachis, CEO and Founder of One Drop. "I'm thrilled to present evidence that says otherwise. We are seeing dramatic improvements in A1c — often achieved with drugs, but rarely, if ever, seen with digital therapeutics and self-care interventions. And, in this case, we're doing it all at scale for less than a fraction of the cost of current standards of care: free."
At this year's American Diabetes Association 77th Scientific Sessions, Evidation Health Inc. reported results of a non-randomized study evaluating the One Drop | Mobile app and One Drop | Experts coaching service. In only 3 months, people with T2D improved their A1c by :
-0.90% among study completers;
-1.00% among active users who used the app and messaged a coach at least once; and
-1.32% among active users with baseline A1c ≥ 9.0%.
Leveraging data collected in-app, One Drop reported these users :
reduced carbohydrate intake by >10 grams per meal;
increased activity by 25 minutes per week;
decreased average blood glucose by 29 mg/dL (a 1.00% A1c reduction);
reduced glycemic variability; and
increased the percentage of in-range blood glucose values.
"With growing numbers of people developing diabetes and increasing options to treat the disease, self-management has become much more complex," said Dr. David Marrero, Director of the Diabetes Translational Research Center at Indiana University School of Medicine and former President of the American Diabetes Association's Healthcare and Education. "The One Drop | Mobile app illuminates the potential for mobile technology to assist persons with diabetes in both tracking the varied elements of their therapy and making more informed self-management decisions. Too many apps promise to improve health, but often don't deliver. It's great to see an app that finally does."
The One Drop | Mobile solution is available for free download worldwide (iOS, and Android) and is available in Russian, French, Chinese, Spanish, Arabic, and English language versions. For more information, contact [email protected].
1 Kumar S, Uppal J, Osborn CY, Heyman M, Juusola J. The accuracy of self-reported A1c among individuals with type 2 diabetes. 2017 Diabetes Abstract Book, vol 67 (Suppl 1A), Late Breaking. 2 Osborn CY, van Ginkel JR, Rodbard D, Heyman M, Marrero DG, Huddleston B, Dachis J, One Drop | Mobile: An Evaluation of Hemoglobin A1c Improvement Linked to App Engagement, JMIR Diabetes 2017;2(2):e21, http://diabetes.jmir.org/2017/2/e21/, doi: 10.2196/diabetes.8039. 3 Kumar S., et al. Impact of a diabetes mobile app with in-app coaching on glycemic control. Late-breaking peer-reviewed poster presentation at the 77th Annual Meeting of the American Diabetes Association; San Diego, CA, USA, June 2017. 4 Osborn C.Y., et al The One Drop mobile app with in-app coaching improves blood glucose and self-care. Peer-reviewed poster presentation at the 77th Annual Meeting of the American Diabetes Association; San Diego, CA, USA, June 2017.
ABOUT ONE DROP One Drop (Informed Data Systems Inc.) is a digital health company harnessing the power of mobile computing and data science to transform the lives of everyone with diabetes worldwide. The One Drop platform is evidence-based and clinically effective. It brings affordable, accessible diabetes care to everyone with diabetes and a smartphone, as well as their insurers and health care providers. Learn more at http://www.onedrop.today/