Project 0 Makes DeFi History, Unlocking Unified Margin Across Multiple Venues for the First Time

First protocol to enable generalized cross-margin across more than one venue; Project 0 is now the largest permissionless prime broker in crypto

NEW YORK, Oct. 13, 2025 /PRNewswire/ -- Project 0, the first DeFi-native prime broker, today announced its integration with Kamino, creating the first instance of generalized cross-margin across multiple DeFi venues. With this release, Project 0 has become the largest permissionless prime broker in crypto, introducing new tools for traders and lenders to manage risk, collateral, and capital efficiency across platforms.

Under the existing DeFi market structure, users are required to overcollateralize separately on each platform, which fragments capital and increases the chance of liquidation even when offsetting positions exist elsewhere. The integration between Project 0 and Kamino directly addresses this problem by consolidating deposits under a single margin framework. Users can now borrow against their Kamino and Project 0 deposits in one click, with unified loan-to-value (LTV), borrow weights, and interest rates. This system also introduces better risk-adjusted parameters by evaluating the user's comprehensive portfolio, rather than treating each position in isolation.

"Solving liquidity fragmentation was the driving force behind founding Project 0. By enabling cross-margin across multiple venues, users can now manage their entire portfolio under a single margin account, addressing a long-standing inefficiency in DeFi and providing clearer oversight of portfolio-wide risk," said MacBrennan Peet, Founder of Project 0. "I'm incredibly proud that we've brought this vision to life with the dedication and expertise of our amazing Project 0 team."

For active traders, the integration makes it possible to arbitrage between Kamino and Project 0 rates with a single pool of credit. This reduces friction, improves capital efficiency, and allows for more effective use of leverage without the need to manage multiple sets of collateral. Lenders also benefit from the integration, as Kamino and Project 0 depositors will be able to access Project 0 incentives and benefit from a unified interface for tracking and managing their positions.

The integration is available today to Project 0's top 5,000 users, who will test the functionality and provide feedback over the next few days. Following the completion of this initial testing period, a staggered public rollout is expected within 3–5 days. This phased approach ensures the system operates smoothly and that the user experience is optimized before wider access. By enabling generalized cross-margin across venues, Project 0 is introducing a capability that has long been discussed but never before implemented in DeFi, integrating leading venues like Kamino into a unified margin protocol.

About Project 0

Project 0 is the first generalized, on-chain, permissionless, multi-venue unified margin protocol. As a DeFi-native trustless prime broker, Project 0 eliminates capital inefficiencies by enabling users to manage their entire DeFi portfolio with unified margin and risk management. The protocol integrates with leading DeFi platforms to provide sophisticated trading and yield strategies while maintaining the composability that makes decentralized finance powerful.

To learn more, users can visit: 0.xyz

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