NEEDHAM, Mass., May 20, 2019 /PRNewswire/ --The National CFIDS Foundation, of Needham, Massachusetts, has provided details regarding its radiation model for Chronic Fatigue Syndrome, a disease that affects millions in the United States. According to Alan Cocchetto, Medical Director for the National CFIDS Foundation, "Our latest model has now identified two key compounds, known as hydroperoxides, that appear to result from cellular injury due to radiation exposure. We believe this finding is of critical importance to the disease process that is present in our patients."
The National CFIDS Foundation identified cardiolipin hydroperoxides as the first key target that acts to disrupt proper functioning of the mitochondria, the energy factory within the cell. The second target, phosphatidylserine hydroperoxides, acts to disrupt red blood cell function resulting in altered tissue oxygenation. Basically, these two hydroperoxides act in concert as cellular toxicants to adversely affect normal cell function.
According to Gail Kansky, National CFIDS Foundation President, "As I understand it, these compounds make for the perfect storm from a disease standpoint since they adversely affect the ability of the body to function properly at many levels. We believe this to be a major tipping point in our understanding of this disease and I truly expect this to have a significant impact on our patients with regards to diagnostic testing and future therapies that will result from these efforts. As such, we are very pleased to be moving full steam ahead on this with our research groups."
Two decades ago, Chernobyl scientists had identified Chronic Fatigue Syndrome as a characteristic aftermath of radioecological catastrophe establishing the first link between radiation exposure and the development of the disease. In 2010, the National CFIDS Foundation became the first organization to report the presence of internal radiation and chromosome damage in its own patient cohort.
According to the National CFIDS Foundation, Chronic Fatigue Syndrome (CFS) is also known as Chronic Fatigue Immune Dysfunction Syndrome (CFIDS) as well as Myalgic Encephalomyelitis (ME). Founded in 1997, the goals of the National CFIDS Foundation are to help fund medical research to find a cause and to expedite appropriate treatments for the disease. Since its inception, the National CFIDS Foundation has provided $4 million dollars in self-directed research grants to global scientists. The National CFIDS Foundation, an all volunteer 501(c)(3) federally approved charity, is funded solely by individual contributions. Additional information can be found on the web at www.ncf-net.org or in The National Forum newsletter. The Foundation can be reached at 781-449-3535.
SOURCE National CFIDS Foundation