NEW YORK, March 21, 2011 /PRNewswire/ -- Reportlinker.com announces that a new market research report is available in its catalogue:
Global Chiral Technology Industry
http://www.reportlinker.com/p090558/Global-Chiral-Technology-Industry.html
This report analyzes the worldwide markets for Chiral Technology in US$ Million, both by Chiral Technology Enabling Products (Intermediates, Analytical, and Others) and by Chiral Technology End Use Markets (Pharmaceuticals, and Agrochemicals). The report provides separate comprehensive analytics for the US, Japan, Europe, and Rest of World. Annual estimates and forecasts are provided for the period 2007 through 2015. Also, a seven-year historic analysis is provided for these markets. The report profiles 38 companies including many key and niche players worldwide such as Albemarle Corporation, BASF AG, Cambrex Corp., Chiral Quest Inc., Dalco ChromTech AB, Daicel Chemical Industries Ltd., Chiral Technologies Worldwide, Chiral Technologies, Inc., Chiral Technologies Europe, DSM Pharmaceutical Products, Johnson Matthey PLC, Regis Technologies Inc., Shasun Chemicals and Drugs Limited, Solvias, Sigma Aldrich Corp, and Suven Life Sciences Ltd. Market data and analytics are derived from primary and secondary research. Company profiles are mostly extracted from URL research and reported select online sources.
1. INTRODUCTION, METHODOLOGY & PRODUCT DEFINITIONS 1
Study Reliability and Reporting Limitations 1
Disclaimers 2
Data Interpretation & Reporting Level 3
Quantitative Techniques & Analytics 3
Product Definitions and Scope of Study 3
Chiral Technology Enabling Products 4
Chiral Intermediates 4
Analytical Products 4
Other Products 4
Chiral Technology End-Use Markets 5
Pharmaceuticals 5
Agrochemicals 5
2. MARKET OVERVIEW 6
Bright Outlook for the Global Chiral Technology Market 6
Analysis by Product Segments and End use Markets 6
Table 1: World Chiral Technology Market by Product Segment
(2009): Percentage Share Breakdown by Value Sales for Chiral
Intermediates, Chiral Analytical Products, and Others
(includes corresponding Graph/Chart) 6
Good Tidings for Chiral Technology 7
Market Drivers 8
Demand for Chiral-based Therapeutic Drugs Augments Growth 8
New Legislations Push Chiral Technology Demand 8
Key Market Trends 8
Organizations Extend Approaches 8
Companies' Association with Universities 9
Trends in Chiral Processes 9
Increasing Reliance on Generic Approaches 9
Predominant Use of Polysaccharides Derivatives as CSPs 9
Automation: Introduction of Instruments Supporting Chiral
Processes, a Growing Trend 9
3. CHIRAL TECHNOLOGY 10
An Insight into Chiral Technology 10
Techniques Used for Achieving Single-Isomers 10
Table 2: World Chiral Technology Market (2002 & 2010):
Percentage Breakdown of Revenues by Techniques- Traditional
Methods, Asymmetric Methods, and Biological Methods (includes
corresponding Graph/Chart) 11
Importance and Advancements 11
4. CHIRAL TECHNOLOGY - AN OVERVIEW 13
Definitions 13
Chiral Technology Enabling Products 13
Chiral Intermediates 13
Analytical Products 13
Other Products 13
Chiral Technology End-Use Markets 14
Pharmaceuticals 14
Agrochemicals 14
Description 14
Functioning of Chiral Molecules 15
Chiral Preparation Process 15
Traditional Methods 15
Biological Methods 16
Asymmetric Methods 16
Chiral Separation 17
Factors Influencing the Efficacy of Chiral Separations 17
Recent Approaches in Chiral Separations 17
Extensive Use of Supercritical Fluid Chromatography (SFC) 17
Chromatography - The Widely Used Method for Separation 18
How it Works? 18
Chiral Mobile Phase Additive (CMPA) 19
Chiral Stationary Phase (CSP) 19
List of Newly Introduced Generic Versions of Derivatized
Amylose and Cellulose Phases 20
Challenges and Novel Concepts in the Development of Chiral
Stationary Phases 20
Novel Concepts 20
Chiral Recognition 21
Protein Chiral Stationary Phases 21
Carbohydrate Columns 21
Pirkle Columns 21
Crystallization 22
Solvent Extraction 22
Kinetic Resolution 23
Capillary Electrophoresis 23
Receptor Based Resolution 23
Miscellaneous Separative Techniques 24
Chiral Synthesis 24
5. CHIRAL TECHNOLOGY - DEVELOPMENT VS ACQUISITION 25
In-House Creation & Development 25
Acquisition of Technology 25
"Economics" of Chiral Technology 26
6. CHIRAL ANALYSIS 27
Chiral Analysis: A Primer 27
Chiral Analysis Products 27
Chiral Analytical Chromatography 27
Chiral Liquid Chromatography 27
Supercritical Fluid Chromatography - Substitute to LC for
Enantiomer Separations 28
Chiral Gas Chromatography 28
Chiral Simulated Moving Bed Chromatography 28
Partition Chromatography 28
Adsorption Chromatography 29
Computer Assisted Resolution 29
Chiral Polarimetry 29
Other Chiral Analytical Techniques 30
Calorimetry 30
Differential Scanning Calorimetry (DSC) 30
Enzymatic Assay 30
Immunoassay 30
Isotope Dilution 31
Nuclear Magnetic Resonance (NMR) 31
X-Ray Crystallography 31
7. APPLICATION MARKETS 32
Pharmaceuticals - The Largest Market 32
Changing Face of the Pharmaceutical Industry: A Review 32
Analysis of Chiral Drugs 32
Select Companies Involved in Chiral Technology Market 33
Table 3: Single-Enantiomer Drugs Market Worldwide (2006- A
Recent past Perspective): Sales of Select Leading Brands
(In US$ Billion) (includes corresponding Graph/Chart) 34
Drugs Built on Chiral Technology 34
Analgesics 34
Anesthetics 35
Anti-Infective Products 35
Cardiovascular System (CVS) Products 35
Angiotensin-Converting Enzyme (ACE) Inhibitors 35
Beta-Blockers 35
Calcium Channel Blockers 36
Diuretics 36
Vasodilators 36
Central Nervous System (CNS) Agents 36
Anticonvulsants 36
Sedatives and Tranquilizers 36
Stimulants and Antidepressants 36
Oncogenic (Cancer-Treatment) Products 37
Biochemicals 37
Oligonucleotides 37
Oxyacids 38
Amino Acids 38
Sugars and Other Oligosaccharides 39
Vitamins 39
Peptides 40
Pesticides - A Thriving Market 41
Herbicides 41
Insecticides 41
Fungicides 42
Other Products 42
Liquid Crystals 42
Flavor and Aroma Chemicals 43
8. CHIRAL ISOMERISM 44
Organic Chemical Isomerism Types 44
Structural Isomerism 44
Chain Isomerism 44
Position Isomerism 44
Functional Group Isomerism 44
Stereoisomerism 44
Dynamic Isomerism (Tautomerism) 45
Patents 45
9. REGULATORY & ENVIRONMENTAL ISSUES- A REVIEW 46
10. PRODUCT INTRODUCTIONS/INNOVATIONS 47
Phenomenex Introduces Chiral Screening Service 47
AminoLogics Develops a Novel Chiral Converting Molecule for
Amino Acids 47
Chiral Technologies Worldwide to Display 3-im and Protein-
based Reversed Phase Columns 47
Chiral Technologies Introduces 3µm Chiral Stationary Phases
for Rapid Analysis 48
Chiral Technologies Introduces 5µm Versions of Polysaccharide
-Based Chiral Stationary 48
Semba Launches Semba Octave™ Chromatography System 48
Modular SFC to Launch Chiral Centrifugal Fraction Collector
and Sample Concentration System 49
Chiral Technologies Introduces New Versions of Immobilized IC
and IA Chiral Phases 49
PDR-Chiral Develops AutoMDS for Automated Screening of Chiral
and Achiral Substances 50
Waters Introduces New Products Under the UPLC Line 50
11. PRODUCT INTRODUCTIONS/INNOVATIONS IN THE RECENT PAST- A
PERSPECTIVE BUILDER 51
Sigma-Aldrich/Supelco Introduces Astec CHIROBIOTIC™ Chiral
HPLC Columns 51
Sigma-Aldrich/Supelco Introduces Astec CYCLOBOND™ Chiral HPLC
Columns 51
Chiral Technologies Introduces CHIRALPAK® IC Columns Under
Polysaccharide Product Range 51
Degussa Develops Novel Processes to Synthesize (S) CAP 52
Regis Technologies, Inc. Launches RegisPack Chiral Columns 52
Sigma-Aldrich Introduces ChiroSolv™ Kits 52
Sigma-Aldrich Launches Ascentis Express HPLC Columns 53
Evolved Nanomaterial Releases Revolutionary Analytical Chiral
Column 53
BASF Develops Novel Process to Produce Chiral Intermediates 53
Sepiatech Launches Sepmatix Parallel HPLC system 53
MACHEREY-NAGEL Launches Novel NUCLEOCEL CSP Columns 54
Eksigent to Launch Express™ HPLC System 54
Chiral Quest Launches C3 TunePhos 55
12. RECENT INDUSTRY ACTIVITY 56
WR Grace Takes Over Synthetech 56
Daicel Chiral to Start a New Branch in Beijing 56
Saltigo Concludes Process Development Agreement with Reuter
Chemische 56
Chiral Technologies Europe Inks Global Licensing Agreement
with University of Vienna 56
Shasun Announces Change of Name 57
CT Worldwide Announces the Launch of a Novel Microsite 57
Chiral Technologies Partners with Vanderbilt University's
Program in Drug Discovery 57
DSM Renews Co-Operation Agreement with Fudan University 57
Chiral Technologies Europe Inks Distribution Agreement with
HICHROM 58
Dow Sells Dowpharma Small Molecules Business 58
Daicel Chemical Establishes New Subsidiary in China 59
Chiral Technologies Europe Takes Over ChromTech 59
Cambrex to Buy ProSyntest AS 59
13. CORPORATE ACTIVITY IN THE RECENT PAST- A PERSPECTIVE BUILDER 60
Johnson Matthey and X-Zyme Sign Licensing Agreement 60
Chiral Quest Starts a New Production Facility 60
Chiral Quest Completes Reverse Merger with Surg II 60
DSM and IEP Extend Partnership 60
Shasun Chemicals Acquires Rhodia Pharma Solutions 60
Sigma-Aldrich Corp Acquires Astec 61
Solvias Receives License for MeOBIPHEP Catalyst Technology 61
Codexis Acquires Juelich Fine Chemicals 61
ChiroBlock Exits from Chiral Compounds Business 61
Chiral Quest Opens New Facility in China 61
Chiral Quest to Supply C3 TunePhos to Phoenix Chemicals 61
Lonza and Codexis Sign Agreement for Biocatalysis Process 62
DSM Signs Licensing Agreement with Chiral Quest 62
Chiral Quest Signs Distribution Agreement with Aldrich Chemical 62
BASF and Solvias to Collaborate on Chiral Molecule Development 62
Chiral Quest and Avantium Enter into Partnership 62
14. FOCUS ON SELECT PLAYERS 63
Albemarle Corporation (USA) 63
BASF SE (Germany) 63
Cambrex Corp. (USA) 63
Chiral Quest Inc. (US) 64
Dalco ChromTech AB (Sweden) 64
Daicel Chemical Industries Ltd. (Japan) 64
Chiral Technologies Worldwide 65
Chiral Technologies, Inc. (USA) 65
Chiral Technologies Europe (France) 65
DSM Pharmaceutical Products (The Netherlands) 65
Johnson Matthey PLC (UK) 66
Regis Technologies, Inc. (USA) 66
Shasun Pharmaceuticals Limited (India) 66
Solvias (Switzerland) 67
Sigma Aldrich Corp. (USA) 67
Suven Life Sciences Ltd. (USA) 67
15. GLOBAL MARKET PERSPECTIVE 69
Table 4: World Recent Past, Current & Future Analysis for
Chiral Technology Enabling Products by Geographic Region - US,
Japan, Europe, and Rest of World Markets Independently
Analyzed with Annual Sales Figures in US$ Million for Years
2007 through 2015 (includes corresponding Graph/Chart) 69
Table 5: World Historic Review for Chiral Technology Enabling
Products by Geographic Region - US, Japan, Europe, and Rest of
World Markets Independently Analyzed with Annual Sales Figures
in US$ Million for Years 2000 through 2006 (includes
corresponding Graph/Chart) 70
Table 6: World 11-Year Perspective for Chiral Technology
Enabling Products by Geographic Region - Percentage Breakdown
of Value Sales for US, Japan, Europe, and Rest of World
Markets for Years 2005, 2010 & 2015 (includes corresponding
Graph/Chart) 71
Table 7: World Recent Past, Current & Future Analysis for
Chiral Intermediates by Geographic Region - US, Japan, Europe,
and Rest of World Markets Independently Analyzed with Annual
Sales Figures in US$ Million for Years 2007 through 2015
(includes corresponding Graph/Chart) 72
Table 8: World Historic Review for Chiral Intermediates by
Geographic Region - US, Japan, Europe, and Rest of World
Markets Independently Analyzed with Annual Sales Figures in
US$ Million for Years 2000 through 2006 (includes
corresponding Graph/Chart) 73
Table 9: World 11-Year Perspective for Chiral Intermediates by
Geographic Region - Percentage Breakdown of Value Sales for
US, Japan, Europe, and Rest of World Markets for Years 2005,
2010 & 2015 (includes corresponding Graph/Chart) 74
Table 10: World Recent Past, Current & Future Analysis for
Chiral Analytical Products by Geographic Region - US, Japan,
Europe, and Rest of World Markets Independently Analyzed with
Annual Sales Figures in US$ Million for Years 2007 through
2015 (includes corresponding Graph/Chart) 75
Table 11: World Historic Review for Chiral Analytical Products
by Geographic Region - US, Japan, Europe, and Rest of World
Markets Independently Analyzed with Annual Sales Figures in
US$ Million for Years 2000 through 2006 (includes
corresponding Graph/Chart) 76
Table 12: World 11-Year Perspective for Chiral Analytical
Products by Geographic Region - Percentage Breakdown of Value
Sales for US, Japan, Europe, and Rest of World Markets for
Years 2005, 2010 & 2015 (includes corresponding Graph/Chart) 77
Table 13: World Recent Past, Current & Future Analysis for
Other Chiral Technology Enabling Products by Geographic Region
- US, Japan, Europe, and Rest of World Markets Independently
Analyzed with Annual Sales Figures in US$ Million for Years
2007 through 2015 (includes corresponding Graph/Chart) 78
Table 14: World Historic Review for Other Chiral Technology
Enabling Products by Geographic Region - US, Japan, Europe,
and Rest of World Markets Independently Analyzed with Annual
Sales Figures in US$ Million for Years 2000 through 2006
(includes corresponding Graph/Chart) 79
Table 15: World 11-Year Perspective for Other Chiral
Technology Enabling Products by Geographic Region - Percentage
Breakdown of Value Sales for US, Japan, Europe, and Rest of
World Markets for Years 2005, 2010 & 2015 (includes
corresponding Graph/Chart) 80
Table 16: World Recent Past, Current & Future Analysis for
Chiral Technology in Pharmaceuticals by Geographic Region -
US, Japan, Europe, and Rest of World Markets Independently
Analyzed with Annual Sales Figures in US$ Million for Years
2007 through 2015 (includes corresponding Graph/Chart) 81
Table 17: World Historic Review for Chiral Technology in
Pharmaceuticals by Geographic Region - US, Japan, Europe, and
Rest of World Markets Independently Analyzed with Annual Sales
Figures in US$ Million for Years 2000 through 2006 (includes
corresponding Graph/Chart) 82
Table 18: World 11-Year Perspective for Chiral Technology in
Pharmaceuticals by Geographic Region - Percentage Breakdown of
Value Sales for US, Japan, Europe, and Rest of World Markets
for Years 2005, 2010 & 2015 (includes corresponding
Graph/Chart) 83
Table 19: World Recent Past, Current & Future Analysis for
Chiral Technology in Agrochemicals by Geographic Region - US,
Japan, Europe, and Rest of World Markets Independently
Analyzed with Annual Sales Figures in US$ Million for Years
2007 through 2015 (includes corresponding Graph/Chart) 84
Table 20: World Historic Review for Chiral Technology in
Agrochemicals by Geographic Region - US, Japan, Europe, and
Rest of World Markets Independently Analyzed with Annual Sales
Figures in US$ Million for Years 2000 through 2006 (includes
corresponding Graph/Chart) 85
Table 21: World 11-Year Perspective for Chiral Technology in
Agrochemicals by Geographic Region - Percentage Breakdown of
Value Sales for US, Japan, Europe, and Rest of World Markets
for Years 2005, 2010 & 2015 (includes corresponding
Graph/Chart) 86
16. THE UNITED STATES 87
A.Market Analysis 87
Overview 87
B.Market Analytics 88
Table 22: US Recent Past, Current and Future Analysis for
Chiral Technology Enabling Products by Product Segment -
Intermediates, Analytical, and Other Markets Independently
Analyzed with Annual Sales Figures in US$ Million for Years
2007 through 2015 (includes corresponding Graph/Chart) 88
Table 23: US Historic Review for Chiral Technology Enabling
Products by Product Segment - Intermediates, Analytical, and
Other Markets Independently Analyzed with Annual Sales
Figures in US$ Million for Years 2000 through 2006 (includes
corresponding Graph/Chart) 89
Table 24: US 11-Year Perspective for Chiral Technology
Enabling Products by Product Segment - Percentage Breakdown
of Value Sales for Intermediates, Analytical, and Other
Markets for Years 2005, 2010 & 2015 (includes corresponding
Graph/Chart) 90
Table 25: US Recent Past, Current & Future Analysis for
Chiral Technology by End-Use Segment - Pharmaceuticals, and
Agrochemicals Markets Independently Analyzed with Annual
Sales Figures in US$ Million for Years 2007 through 2015
(includes corresponding Graph/Chart) 91
Table 26: US Historic Review for Chiral Technology by
End-Use Segment - Pharmaceuticals, and Agrochemicals Markets
Independently Analyzed with Annual Sales Figures in US$
Million for Years 2000 through 2006 (includes corresponding
Graph/Chart) 92
Table 27: US 11-Year Perspective for Chiral Technology by
End-Use Segment - Percentage Breakdown of Value Sales for
Pharmaceuticals, and Agrochemicals Markets for Years 2005,
2010 & 2015 92
17. JAPAN 93
A.Market Analysis 93
Outlook 93
B.Market Analytics 93
Table 28: Japanese Recent Past, Current & Future Analysis
for Chiral Technology Enabling Products by Product Segment -
Intermediates, Analytical, and Other Markets Independently
Analyzed with Annual Sales Figures in US$ Million for Years
2007 through 2015 (includes corresponding Graph/Chart) 93
Table 29: Japanese Historic Review for Chiral Technology
Enabling Products by Product Segment - Intermediates,
Analytical, and Other Markets Independently Analyzed with
Annual Sales Figures in US$ Million for Years 2000 through
2006 (includes corresponding Graph/Chart) 94
Table 30: Japanese 11-Year Perspective for Chiral Technology
Enabling Products by Product Segment - Percentage Breakdown
of Value Sales for Intermediates, Analytical, and Other
Markets for Years 2005, 2005 & 2015 (includes corresponding
Graph/Chart) 95
Table 31: Japanese Recent Past, Current & Future Analysis
for Chiral Technology by End-Use Segment - Pharmaceuticals,
and Agrochemicals Markets Independently Analyzed with Annual
Sales Figures in US$ Million for Years 2007 through 2015
(includes corresponding Graph/Chart) 96
Table 32: Japanese Historic Review for Chiral Technology by
End-Use Segment - Pharmaceuticals, and Agrochemicals Markets
Independently Analyzed with Annual Sales Figures in US$
Million for Years 2011 through 2015 (includes corresponding
Graph/Chart) 97
Table 33: Japanese 11-Year Perspective for Chiral Technology
by End-Use Segment - Percentage Breakdown of Value Sales for
Pharmaceuticals and Agrochemicals Markets for Years 2005,
2005 & 2015 97
18. EUROPE 98
A.Market Analysis 98
Overview 98
B.Market Analytics 99
Table 34: European Recent Past, Current & Future Analysis
for Chiral Technology Enabling Products by Product Segment -
Intermediates, Analytical, and Other Markets Independently
Analyzed with Annual Sales Figures in US$ Million for Years
2007 through 2015 (includes corresponding Graph/Chart) 99
Table 35: European Historic Review for Chiral Technology
Enabling Products by Product Segment - Intermediates,
Analytical, and Other Markets Independently Analyzed with
Annual Sales Figures in US$ Million for Years 2000 through
2006 (includes corresponding Graph/Chart) 100
Table 36: European 11-Year Perspective for Chiral Technology
Enabling Products by Product Segment - Percentage Breakdown
of Value Sales for Intermediates, Analytical, and Other
Markets for Years 2005, 2010 & 2015 (includes corresponding
Graph/Chart) 101
Table 37: European Recent Past, Current and Future Analysis
for Chiral Technology by End-Use Segment - Pharmaceuticals,
and Agrochemicals Markets Independently Analyzed with Annual
Sales Figures in US$ Million for Years 2007 through 2015
(includes corresponding Graph/Chart) 102
Table 38: European Historic Review for Chiral Technology by
End-Use Segment - Pharmaceuticals, and Agrochemicals Markets
Independently Analyzed with Annual Sales Figures in US$
Million for Years 2000 through 2006 (includes corresponding
Graph/Chart) 103
Table 39: European 11-Year Perspective for Chiral Technology
by End-Use Segment - Percentage Breakdown of Value Sales for
Pharmaceuticals, and Agrochemicals Markets for Years 2005,
2010 & 2015 103
19. REST OF WORLD 104
A.Market Analysis 104
Outlook 104
India 104
Chiral Drugs in the Indian Market 104
China-A Hub for Pharmaceutical Manufacturing 104
B.Market Analytics 105
Table 40: Rest of World Recent Past, Current & Future
Analysis for Chiral Technology Enabling Products by Product
Segment - Intermediates, Analytical, and Other Markets
Independently Analyzed with Annual Sales Figures in US$
Million for Years 2007 through 2015 (includes corresponding
Graph/Chart) 105
Table 41: Rest of World Historic Review for Chiral
Technology Enabling Products by Product Segment -
Intermediates, Analytical, and Other Markets Independently
Analyzed with Annual Sales Figures in US$ Million for Years
2000 through 2006 (includes corresponding Graph/Chart) 106
Table 42: Rest of World 11-Year Perspective for Chiral
Technology Enabling Products by Product Segment - Percentage
Breakdown of Value Sales for Intermediates, Analytical, and
Other Markets for Years 2005, 2010 & 2015 (includes
corresponding Graph/Chart) 107
Table 43: Rest of World Recent Past, Current & Future
Analysis for Chiral Technology by End-Use Segment -
Pharmaceuticals, and Agrochemicals Markets Independently
Analyzed with Annual Sales Figures in US$ Million for Years
2007 through 2015 (includes corresponding Graph/Chart) 108
Table 44: Rest of World Historic Review for Chiral
Technology by End-Use Segment - Pharmaceuticals, and
Agrochemicals Markets Independently Analyzed with Annual
Sales Figures in US$ Million for Years 2000 through 2006
(includes corresponding Graph/Chart) 109
Table 45: Rest of World 11-Year Perspective for Chiral
Technology by End-Use Segment - Percentage Breakdown of
Value Sales for Pharmaceuticals, and Agrochemicals Markets
for Years 2005, 2010 & 2015 109
COMPETITIVE LANDSCAPE
Total Companies Profiled: 38 (including Divisions/Subsidiaries - 48)
------------------------------------------
Region/Country Players
------------------------------------------
The United States 29
Canada 1
Japan 2
Europe 12
France 4
Germany 1
The United Kingdom 2
Italy 1
Rest of Europe 4
Asia-Pacific (Excluding Japan) 4
------------------------------------------
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