Skinbetter Science Advances Retinoid Science with New AlphaRet Clinical Findings During National Retinoid Week

LOS ANGELES, Sept. 14, 2026 /PRNewswire/ -- skinbetter science, the creator of National Retinoid Week and the #1 dermatologist-recommended retinoid brand, continues to lead the evolution of the retinoid category as it kicks off its third annual National Retinoid Week with new clinical findings that further demonstrate the brand's commitment to advancing retinoid science, innovation and education.

Created by skinbetter science to help shape a more informed conversation around retinoid use, National Retinoid Week reflects the brand's ongoing leadership in making expert-backed education more accessible and empowering consumers to find effective retinoid solutions they can use consistently. Following the 10-year anniversary of the brand's award-winning AlphaRet Technology earlier this year, new clinical findings further reinforce the approach that has defined AlphaRet for a decade: delivering visible retinoid results with a high level of tolerability.

In the new study, 98% of retinoid-sensitive users agreed that AlphaRet Overnight Cream can be used nightly, demonstrating the potential for consistent use even among consumers who have historically struggled to incorporate a retinoid into their skincare routine.

Clinical findings from the 12-week clinical study on patients with retinoid intolerance showcase*:

• 98% agreed AlphaRet Overnight Cream can be used nightly
• 95% agreed skin felt smoother, firmer and comfortable 
• +42% improvement in hydration at 12 weeks
• +48% improvement in skin dullness at 12 weeks

"As we celebrate our third National Retinoid Week, we're continuing our commitment to advancing the category and helping more consumers better understand how to confidently incorporate retinoids into their routines," says Geneviève Bibeau, General Manager of skinbetter science USA. "At skinbetter science, we believe consumers shouldn't have to choose between efficacy and tolerability. AlphaRet was created to challenge that compromise through advanced science that delivers prescription-strength efficacy and visible results with a high level of tolerability. National Retinoid Week allows us to bring that science to life through dermatologist-led education, expert partnerships and engaging social programming that connects consumers with credible information and helps them make more informed choices for their individual skin needs." 

skinbetter partner Annie Gonzalez, MD, FAAD Board-certified Dermatologist and Founder of Glösense Dermatology & Aesthetics shares,"what impressed me most about this study wasn't the efficacy data - it was who they tested it on. These were self-identified retinoid-intolerant patients, the ones who'd already tried and failed other retinoids and even in that group, skinbetter science saw extremely high tolerability over twelve weeks. That's impressive!" 

As part of the week, skinbetter science will also bring retinoid education to consumers through dermatologist-led content and social activations, while offering exclusive gifts and promotions on skinbetter.com.

skinbetter science AlphaRet Collection and products can be purchased exclusively on www.skinbetter.com or through an authorized physician provider. To learn more and find an authorized skinbetter science physician near you, please visit www.skinbetter.com.

Study Details:
*A 12-week multicenter, dermatologist-led clinical study evaluated nightly use of AlphaRet Overnight Cream in participants with self-identified retinoid sensitivity and mild-to-moderate photoaging. (N=56) 

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About skinbetter science
skinbetter science was formed in 2016 to establish a new biotech-based approach to skincare, built on three pillars: science, care and results. The team is committed to a technology pipeline of scientific innovation across multiple skincare categories, rigorous clinical substantiation of safety and efficacy of its products, as well as partnership with dermatologists, plastic surgeons, and other healthcare professionals in the aesthetic medical community in order to deliver best-in-class skincare solutions to their patients. skinbetter science is available exclusively through the leading dermatology, plastic surgery and medical aesthetics practices nationwide. To find an authorized skinbetter science physician near you, please visit www.skinbetter.com.

SOURCE Skinbetter Science