The Changing Role of Natural Products in Drug Discovery
NEW YORK, July 19, 2011 /PRNewswire/ -- Reportlinker.com announces that a new market research report is available in its catalogue:
The Changing Role of Natural Products in Drug Discovery
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Introduction
This report reveals how natural products have been of value to the pharmaceutical industry and yet how relatively little of their potential has been explored. It assesses strategies for exploring their continued potential and examines the therapeutic areas in which natural products may offer the greatest benefit. The report also profiles specialist companies.
Features and benefits
* Understand how small a fraction of natural products has been explored for pharmaceutical potential.
* Understand how natural products offer access to underexploited but biologically relevant regions of chemical space
* Identify in which therapeutic areas the exploration of natural products offers better prospects of success.
* Gain insight into the different approaches used for the exploitation of natural products and understand the influence of past successes and failures.
* Assess the value of specialist companies as possible partners or service providers.
Highlights
Natural products have been the source of most classes of antibacterial drugs, a field where target-driven medicinal chemistry programs have proved highly unsuccessful. Natural products have also been the source of, or inspiration for, the majority of older anticancer drugs.
Natural products often have highly novel, albeit complex, chemical structures that have evolved to support biological activity. They thus represent potentially valuable chemical leads in the development of drugs.
Very large numbers of microbial strains and marine natural products have yet to be identified, or explored for their potential therapeutic utility. Nonetheless, the sole pursuit of the development of natural products as therapeutic agents is a risky strategy for a company.
Your key questions answered
* How do natural products offer value in the development of new drugs?
* Who could provide a useful partner in trying to exploit natural product resources?
* What therapeutic areas offer better prospects for commercially exploiting natural product derived therapeutics?
* How do natural products offer scope for innovation in developing new drugs?
* What are the potential problems in trying to exploit natural products?
Executive Summary
Introduction
Use of natural products in drug discovery
Exploiting natural resources
Corporate strategies
Case histories
Specialist companies
Future outlook
About the author
Disclaimer
Introduction
Summary
Introduction
Folk medicine
Use of natural products
From extracts to pure chemicals
Use of natural products in drug discovery
Summary
Overview
Pharmacological tools
Chemical leads
Marketed therapeutics
Infectious diseases
Cancer
Inflammatory disease
Cardiovascular disease
Metabolic diseases
CNS disease
Recent approvals
Exploiting natural resources
Summary
Introduction
Chemical entities
Biosynthetic pathways
Accessing novel chemical space
Disadvantages
Biological sources
Botanical resources
Microbiological resources
Marine resources
Corporate strategies
Summary
Introduction
Exclusive access to natural resources
Prospecting for natural products
Evaluating natural products
Drawing from traditional medicines
Natural products as the sole corporate focus
Case histories
Summary
Introduction
Aspirin
?-Lactam antibiotics
Taxanes
Epothilones
Discodermolide
Eribulin
Artemisinin
Specialist companies
Summary
Introduction
Biotica Technology
EntreChem Biotechnology
GW Pharma
Hypha Discovery
Magellan BioScience
MerLion Pharmaceuticals
Nereus Pharmaceuticals
PharmaMar
Phynova
Phytopharm
PhytoPharmacon
PhytoQuest
Defunct companies
CalBioMarine Technologies
Cerylid Biosciences
Calyx Therapeutics
Shaman Pharmaceutical
Summary of compounds in development
Summary of natural product screening collections
The role of academia
Future outlook
Summary
Introduction
Continued role for natural products
Licensing opportunities
Key opportunities
Oncology
Infectious diseases
Assessment
Appendix
Glossary/Abbreviations
Bibliography
To order this report:
Drug Discovery and Development Industry: The Changing Role of Natural Products in Drug Discovery
Drug Discovery and Development Business News
Check our Company Profile, SWOT and Revenue Analysis!
CONTACT
Nicolas Bombourg
Reportlinker
Email: [email protected]
US: (805)652-2626
Intl: +1 805-652-2626
SOURCE Reportlinker
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