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The Zacks Analyst Blog Highlights:Clovis, Biogen, Halozyme, Ariad and Chart Industries

Zacks Investment Research, Inc., www.zacks.com. (PRNewsFoto/Zacks Investment Research) (PRNewsFoto/ZACKS INVESTMENT RESEARCH)

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Zacks Investment Research, Inc.

Jun 12, 2014, 09:30 ET

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CHICAGO, June 12, 2014 /PRNewswire/ -- Zacks.com announces the list of stocks featured in the Analyst Blog. Every day the Zacks Equity Research analysts discuss the latest news and events impacting stocks and the financial markets. Stocks recently featured in the blog include the Clovis (Nasdaq:CLVS-Free Report), Biogen (Nasdaq:BIIB-Free Report), Halozyme (Nasdaq:HALO-Free Report), Ariad (Nasdaq:ARIA-Free Report) andChart Industries Inc. (Nasdaq:GTLS-Free Report).

Today, Zacks is promoting its ''Buy'' stock recommendations. Get #1Stock of the Day pick for free.

Here are highlights from Wednesday's Analyst Blog:

Biotech Stock Roundup

Apart from the usual study results, last week's top stories include the lifting of clinical holds for two experimental treatments as well as the granting of fast track and orphan drug status to a couple of candidates.

Clovis (Nasdaq:CLVS-Free Report) Down on Safety Concerns: Clovis' shares slumped 19.9% on safety concerns about its experimental lung cancer treatment, CO-1686. Clovis had presented encouraging data on the treatment at the annual meeting of the American Society of Clinical Oncology (ASCO). However, about 22% of patients were found to have high sugar, which is associated with diabetes. Clovis is trying to bring its cancer treatment ahead of AstraZeneca which has a similar candidate in its portfolio. But safety concerns could put a lid on progress.

Another Hemophilia Win for Biogen (Nasdaq:BIIB-Free Report): Biogen now has another hemophilia treatment in its portfolio with the FDA approving Eloctate (hemophilia A). Hemophilia A, a rare, chronic, genetic disorder under which blood clotting ability is impaired, can lead to recurrent and extended bleeding episodes.

Earlier this year, Biogen's hemophilia B treatment Alprolix was approved in the U.S. A convenient dosing schedule (supported by a longer duration of action and a suitable safety profile) could help these products capture share from existing products in the hemophilia market.

FDA Lifts Clinical Hold, Halozyme (Nasdaq:HALO-Free Report) Soars: The FDA lifted its clinical hold on Halozyme's mid-stage study on PEGPH20 for pancreatic cancer. This removes uncertainty regarding this program which had run into trouble earlier this year due to safety concerns. The study will continue under a revised protocol. Shares were up 12%.

Partial Clinical Hold on Ariad (Nasdaq:ARIA-Free Report) Study Lifted: Ariad's investors finally had something to cheer about with the FDA lifting a partial clinical hold on the company's phase II study of Iclusig in patients with refractory metastatic and/or unresectable gastrointestinal stromal tumors. New patients can now be enrolled in this study. Ariad also presented initial data which indicate Iclusig's anti-tumor activity in patients with advanced GIST, particularly in patients with KIT exon 11 mutations. Shares were up 7.4%.

Chart Industries Downgraded to Strong Sell

Zacks Investment Research downgraded Chart Industries Inc. (Nasdaq:GTLS-Free Report) to a Zacks Rank #5 (Strong Sell) on Jun 10, 2014. Going by the Zacks model, companies holding a Zacks Rank #5 have strong chances of performing worse than the broader market.

Why the Downgrade?

Chart Industries reported disappointing results for first-quarter 2014. The company's earnings were 41 cents per share, down from 54 cents per share earned in the year-ago quarter. Also, the bottom-line result lagged the Zacks Consensus Estimate of 62 cents per share.  

Revenues decreased 3% year over year to $266.2 million due to weak performance in the BioMedical segment. Orders declined 8.6% sequentially while backlog inched down 1% at the quarter-end. Gross profit slipped 2.4% year over year with gross margin standing at 29.1%.

For 2014, Chart Industries revised its sales guidance downward to a range of $1.25−$1.3 billion from the prior expectation of $1.3−$1.35 billion. Earnings are anticipated to lie within $3.00−$3.40 per share, down from the $3.10−$3.50 range projected earlier.

Lower-than-expected results and lowered sales and earnings per share guidance for 2014 triggered downward revisions in the earnings estimates for Chart Industries. Over the last 60 days, the Zacks Consensus Estimate has decreased 5.2% to $3.09 for 2014 and 5.5% to $3.99 for 2015. Also, the company has an Earnings ESP of -1.33% for second-quarter 2014 and -4.8% for full-year 2014.

Today, Zacks is promoting its ''Buy'' stock recommendations. Get #1Stock of the Day pick for free.

About Zacks Equity Research

Zacks Equity Research provides the best of quantitative and qualitative analysis to help investors know what stocks to buy and which to sell for the long-term.

Continuous coverage is provided for a universe of 1,150 publicly traded stocks. Our analysts are organized by industry which gives them keen insights to developments that affect company profits and stock performance. Recommendations and target prices are six-month time horizons.

Zacks "Profit from the Pros" e-mail newsletter provides highlights of the latest analysis from Zacks Equity Research. Subscribe to this free newsletter today.

About Zacks

Zacks.com is a property of Zacks Investment Research, Inc., which was formed in 1978. The later formation of the Zacks Rank, a proprietary stock picking system; continues to outperform the market by nearly a 3 to 1 margin. The best way to unlock the profitable stock recommendations and market insights of Zacks Investment Research is through our free daily email newsletter; Profit from the Pros. In short, it's your steady flow of Profitable ideas GUARANTEED to be worth your time! Register for your free subscription to Profit from the Pros.

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Past performance is no guarantee of future results. Inherent in any investment is the potential for loss. This material is being provided for informational purposes only and nothing herein constitutes investment, legal, accounting or tax advice, or a recommendation to buy, sell or hold a security. No recommendation or advice is being given as to whether any investment is suitable for a particular investor. It should not be assumed that any investments in securities, companies, sectors or markets identified and described were or will be profitable. All information is current as of the date of herein and is subject to change without notice. Any views or opinions expressed may not reflect those of the firm as a whole. Zacks Investment Research does not engage in investment banking, market making or asset management activities of any securities. These returns are from hypothetical portfolios consisting of stocks with Zacks Rank = 1 that were rebalanced monthly with zero transaction costs. These are not the returns of actual portfolios of stocks. The S&P 500 is an unmanaged index. Visit http://www.zacks.com/performance for information about the performance numbers displayed in this press release.

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SOURCE Zacks Investment Research, Inc.

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