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Type 1 Diabetes Therapeutics - Pipeline Assessment and Market Forecasts to 2018


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Reportlinker

Oct 11, 2011, 06:22 ET

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NEW YORK, Oct. 11, 2011 /PRNewswire/ -- Reportlinker.com announces that a new market research report is available in its catalogue:

Type 1 Diabetes Therapeutics - Pipeline Assessment and Market Forecasts to 2018

http://www.reportlinker.com/p0652964/Type-1-Diabetes-Therapeutics---Pipeline-Assessment-and-Market-Forecasts-to-2018.html#utm_source=prnewswire&utm_medium=pr&utm_campaign=Pathology

Type 1 Diabetes Therapeutics - Pipeline Assessment and Market Forecasts to 2018

Summary

GlobalData, the industry analysis specialist, has released its new report, "Type 1 Diabetes Therapeutics - Pipeline Assessment and Market Forecasts to 2018". The report is an essential source of information and analysis on the global Type 1 Diabetes Therapeutics market. The report identifies the key trends shaping and driving the global Type 1 Diabetes Therapeutics market. The report also provides insights on the prevalent competitive landscape and the emerging players expected to significantly alter the market positioning of the current market leaders. Most importantly, the report provides valuable insights on the pipeline products within the global Type 1 Diabetes Therapeutics sector. This report is built using data and information sourced from proprietary databases, primary and secondary research and in-house analysis by GlobalData's team of industry experts.

Scope

The report provides information on the key drivers and challenges of the Type 1 Diabetes Therapeutics market. Its scope includes -

- Annualized seven key markets (US, France, Germany, Italy, Spain, UK and Japan) Type 1 Diabetes Therapeutics market revenues data from 2005 to 2010, forecast for eight years to 2018.

- Pipeline analysis data providing a split across the different phases, mechanisms of action being developed and emerging trends by seven key markets. Pipeline candidates fall under major therapeutic classes.

- Analysis of the current and future competition in the seven key countries Type 1 Diabetes Therapeutics market.

- Insightful review of the key industry drivers, restraints and challenges. Each trend is independently researched to provide a qualitative analysis of its implications.

- Key topics covered include strategic competitor assessment, market characterization, unmet needs and the implications for the Type 1 Diabetes Therapeutics market.

- Analysis of key recent licensing and partnership agreements in Type 1 Diabetes Therapeutics market

Reasons to buy

The report will enhance your decision making capability. It will allow you to -

- Develop and design your in-licensing and out-licensing strategies through a review of pipeline products and technologies and by identifying the companies with the most robust pipeline.

- Develop business strategies by understanding the trends shaping and driving the global Type 1 Diabetes Therapeutics market.

- Drive revenues by understanding the key trends, innovative products and technologies, market segments and companies likely to impact the global Type 1 Diabetes Therapeutics market in future.

- Formulate effective sales and marketing strategies by understanding the competitive landscape and by analyzing the performance of various competitors.

- Identify emerging players with potentially strong product portfolios and create effective counter-strategies to gain a competitive advantage.

- Organize your sales and marketing efforts by identifying the market categories and segments that present maximum opportunities for consolidations, investments and strategic partnerships.

- What's the next big thing in the global Type 1 Diabetes Therapeutics market landscape? – Identify, understand and capitalize.

1 Table of contents

1 Table of contents 3

1.1 List of Tables 5

1.2 List of Figures 6

2 Type 1 Diabetes Therapeutics - Introduction 7

2.1 Disease Overview 7

2.2 Epidemiology 8

2.3 Etiology and Pathophysiology 8

2.4 Signs and Symptoms 9

2.5 Commonly Used Diagnostic Tests 10

2.6 Treatment and Management Options for Type 1 Diabetes 11

2.6.1 Types of Insulin 11

2.7 GlobalData Pipeline Report Guidance 13

3 Type 1 Diabetes Therapeutics - Market Characterization 14

3.1 Type 1 Diabetes Therapeutics Market Size (2005-2010) - Global 14

3.2 Type 1 Diabetes Therapeutics Market Forecast (2010-2018) - Global 15

3.3 Type 1 Diabetes Therapeutics Market Size (2005-2010) - The US 17

3.4 Type 1 Diabetes Therapeutics Market Forecast (2010-2018) - The US 18

3.5 Type 1 Diabetes Therapeutics Market Size (2005-2010) - France 19

3.6 Type 1 Diabetes Therapeutics Market Forecast (2010-2018) - France 20

3.7 Type 1 Diabetes Therapeutics Market Size (2005-2010) - Germany 21

3.8 Type 1 Diabetes Therapeutics Market Forecast (2010-2018) - Germany 22

3.9 Type 1 Diabetes Therapeutics Market Size (2005-2010) - Italy 23

3.10 Type 1 Diabetes Therapeutics Market Forecast (2010-2018) - Italy 24

3.11 Type 1 Diabetes Therapeutics Market Size (2005-2010) - Spain 25

3.12 Type 1 Diabetes Therapeutics Market Forecast (2010-2018) - Spain 26

3.13 Type 1 Diabetes Therapeutics Market Size (2005-2010) - The UK 27

3.14 Type 1 Diabetes Therapeutics Market Forecast (2010-2018) - The UK 28

3.15 Type 1 Diabetes Therapeutics Market Size (2005-2010) - Japan 29

3.16 Type 1 Diabetes Therapeutics Market Forecast (2010-2018) - Japan 30

3.17 Drivers and Barriers for the Type 1 Diabetes Therapeutics Market 31

3.17.1 Drivers for the Type 1 Diabetes Therapeutics Market 31

3.17.2 Barriers for the Type 1 Diabetes Therapeutics Market 32

3.18 Opportunity and Unmet Need Analysis 32

3.19 Key Takeaway 33

4 Type 1 Diabetes Therapeutics - Competitive Assessment 34

4.1 Overview 34

4.2 Strategic Competitor Assessment 34

4.3 Product Profiles for the Major Marketed Products in the Type 1 Diabetes Therapeutics Market 35

4.3.1 Apidra (insulin glulisine) 35

4.3.2 Humalog (insulin lispro) 37

4.3.3 Novolog (insulin aspart) 39

4.3.4 Lantus (insulin glargine) 40

4.3.5 Levemir (insulin detemir) 43

4.3.6 Symlin (pramlintide acetate) 44

4.4 Key Takeaway 45

5 Type 1 Diabetes Mellitus Therapeutics - Pipeline Assessment 46

5.1 Overview 46

5.2 Strategic Pipeline Assessment 46

5.3 Type 1 Diabetes Therapeutics Pipeline - Pipeline by Phases of Development 47

5.3.1 Type 1 Diabetes Therapeutics - Phase III Pipeline 47

5.3.2 Type 1 Diabetes Therapeutics - Phase II Pipeline 48

5.3.3 Type 1 Diabetes Therapeutics - Phase I Pipeline 49

5.3.4 Type 1 Diabetes Therapeutics - Pre-Clinical Pipeline 50

5.3.5 Type 1 Diabetes Therapeutics - Discovery 50

5.3.6 Technology Trends Analytic Framework 51

5.4 Type 1 Diabetes Therapeutics Market - Pipeline by Mechanism of Action 52

5.5 Type 1 Diabetes Therapeutics - Promising Drugs in Clinical Development 53

5.6 Molecule Profile for Promising Drugs in Clinical Development 53

5.6.1 Degludec (NN1250) 53

5.6.2 DiaPep277 54

5.6.3 Generex Oral-lyn 55

5.7 Others Drugs Profile in Clinical Development 56

5.7.1 Afrezza (insulin human [rDNA origin]) 56

5.7.2 Diamyd 57

5.7.3 Linjeta (formerly known as VIAject) 58

5.7.4 Otelixizumab 59

5.7.5 Teplizumab 60

5.8 Key Takeaway 60

6 Type 1 Diabetes Therapeutics - Clinical Trial Mapping 61

6.1 Clinical Trials by Region and Country 61

6.2 Clinical Trials by Phase 62

6.3 Clinical Trials by Trial Status 63

6.4 Clinical Trial Mapping by Sponsors 64

6.5 Prominent Sponsors 65

6.6 Top Companies Participating in Type 1 Diabetes Therapeutics Clinical Trials 66

7 Type 1 Diabetes Therapeutics - Strategic Assessment 67

7.1 Key Events Impacting the Future Market 67

7.2 Type 1 Diabetes Therapeutics: Implications for Future Market Competition 68

8 Type 1 Diabetes Therapeutics - Future Players 69

8.1 Introduction 69

8.2 Company Profiles 69

8.2.1 BioDelivery Sciences International, Inc 69

8.2.2 Diamyd Medical AB 70

8.2.3 Evotec Aktiengesellschaft 71

8.2.4 GlaxoSmithKline plc 72

8.2.5 Generex Biotechnology Corporation 73

8.2.6 Halozyme Therapeutics, Inc. 74

8.2.7 MacroGenics, Inc. 75

8.2.8 MannKind Corporation 76

8.2.9 Novo Nordisk A/S 77

8.2.10 Other Companies in the Type 1 Diabetes Therapeutics Market 78

9 Type 1 Diabetes Therapeutics - Licensing and Partnership Deals 79

10 Type 1 Diabetes Therapeutics - Appendix 96

10.1 Market Definitions 96

10.2 Abbreviations 96

10.3 Methodology 97

10.3.1 Coverage 97

10.3.2 Secondary Research 97

10.3.3 Forecasting 98

10.3.4 Primary Research 100

10.3.5 Expert Panel Validation 101

10.4 Contact Us 101

10.5 Disclaimer 101

10.6 Bibliography 102

List of Tables

Table 1: Recommended Diagnostic Test for Diabetes Mellitus 10

Table 2: Plasma Blood Glucose and A1C Goals for Type 1 Diabetes By Age Group 10

Table 3: Types of Insulin Preparations 12

Table 4: Type 1 Diabetes Therapeutics Market, Global, Revenue ($m), 2005-2010 14

Table 5: Type 1 Diabetes Therapeutics Market, Global, Forecast ($m), 2010-2018 16

Table 6: Type 1 Diabetes Therapeutics Market, The US, Revenue ($m), 2005-2010 17

Table 7: Type 1 Diabetes Therapeutics Market, The US, Forecasts ($m), 2010-2018 19

Table 8: Type 1 Diabetes Therapeutics Market, France, Revenue ($m), 2005-2010 19

Table 9: Type 1 Diabetes Therapeutics Market, France, Forecasts ($m), 2010-2018 20

Table 10: Type 1 Diabetes Therapeutics Market, Germany, Revenue ($m), 2005-2010 21

Table 11: Type 1 Diabetes Therapeutics Market, Germany, Forecasts ($m), 2010-2018 22

Table 12: Type 1 Diabetes Therapeutics Market, Italy, Revenue ($m), 2005-2010 23

Table 13: Type 1 Diabetes Therapeutics Market, Italy, Forecasts ($m), 2010-2018 24

Table 14: Type 1 Diabetes Therapeutics Market, Spain, Revenue ($m), 2005-2010 25

Table 15: Type 1 Diabetes Therapeutics Market, Spain, Forecasts ($m), 2010-2018 26

Table 16: Type 1 Diabetes Therapeutics Market, The UK, Revenue ($m), 2005-2010 27

Table 17: Type 1 Diabetes Therapeutics Market, The UK, Forecasts ($m), 2010-2018 28

Table 18: Type 1 Diabetes Therapeutics Market, Japan, Revenue ($m), 2005-2010 29

Table 19: Type 1 Diabetes Therapeutics Market, Japan, Forecasts ($m), 2010-2018 30

Table 20: Apidra - Efficacy Result of 26 Week Study Comparing Apidra with Insulin Lispro, 2011 35

Table 21: Apidra - Efficacy Result of 26 Week Study Comparing Apidra with Regular Insulin, 2011 36

Table 22: Apidra - Adverse Reactions Observed in Pooled Studies in Type 1 Diabetic Adults, 2011 36

Table 23: Type 1 Diabetes Therapeutics Market, Humalog, Glycemic Parameters at the End of Treatment Period in Randomized Patients in Three Month Cross Over Studies, 2011 37

Table 24: Humalog - Results of a Two Month Study Comparing the Use of Humalog and Humulin With Sulfonyluria (SU) Therapy, 2011 38

Table 25: Type 1 Diabetes Therapeutics Market, Novolog, Glycemic Parameters at the End of 24 Week Study, 2011 39

Table 26: Type 1 Diabetes Therapeutics Market, Lantus, Clinical Studies Outcome for Efficacy, 2011 41

Table 27: Type 1 Diabetes Therapeutics Market, Lantus, Adverse Events in 28 Week Clinical Trials of Adults and Children With Type 1 Diabetes, 2011 41

Table 28: Type 1 Diabetes Therapeutics Market, Lantus, Clinical Studies Outcome for Safety, 2011 42

Table 29: Levemir - Efficacy Result in 16 Week Non Blinded Study, 2011 43

Table 30: Type 1 Diabetes Therapeutics - Phase III Pipeline, 2011 47

Table 31: Type 1 Diabetes Therapeutics - Phase II Pipeline, 2011 48

Table 32: Type 1 Diabetes Therapeutics - Phase I Pipeline, 2011 49

Table 33: Type 1 Diabetes Therapeutics - Pre-Clinical Pipeline, 2011 50

Table 34: Type 1 Diabetes Therapeutics - Discovery, 2011 50

Table 35: Type 1 Diabetes Therapeutics - Most Promising Drugs in Clinical Development, 2011 53

Table 36: Type 1 Diabetes Therapeutics - Clinical Trials by Country, 2011 61

Table 37: Type 1 Diabetes Therapeutics - Clinical Trials by Phase, 2011 62

Table 38: Type 1 Diabetes Therapeutics - Clinical Trials by Status, 2011 63

Table 39: Type 1 Diabetes Therapeutics - Overall Sponsors, 2011 64

Table 40: Type 1 Diabetes Therapeutics - Prominent Sponsors, 2011 65

Table 41: Type 1 Diabetes Therapeutics - Top Companies Participating in Therapeutics Clinical Trials, 2011 66

Table 42: BioDelivery Sciences International, Inc.– Type 1 Diabetes, Pipeline, 2011 70

Table 43: Diamyd Medical AB – Type 1 Diabetes, Pipeline, 2011 71

Table 44: Evotec – Metabolic Disorder, Pipeline, 2011 72

Table 45: GlaxoSmithKline plc – Metabolic Disorder, Pipeline, 2011 73

Table 46: Generex Biotechnology Corporation–Metabolic Disorder, Pipeline, 2011 74

Table 47: Halozyme Therapeutics–Metabolic Disorder, Pipeline, 2011 75

Table 48: Halozyme Therapeutics–Metabolic Disorder, Pipeline, 2011 75

Table 49: MannKind Corporation –Metabolic Disorder, Pipeline, 2011 76

Table 50: Novo Nordisk A/S – Type 1 Diabetes, Pipeline, 2011 77

Table 51: Type 1 Diabetes Therapeutics Market – Future Players 78

Table 52: Type 1 Diabetes–Global, Deals, 2011 79

List of Figures

Figure 1: Pathogenesis of Type 1 Diabetes 8

Figure 2: Type 1 Diabetes Therapeutics Market, Global, Revenue ($m), 2005-2010 14

Figure 3: Type 1 Diabetes Therapeutics Market, Global, Forecast ($m), 2010-2018 16

Figure 4: Type 1 Diabetes Therapeutics Market, The US, Forecast ($m), 2005-2010 17

Figure 5: Type 1 Diabetes Therapeutics Market, The US, Forecasts ($m), 2010-2018 18

Figure 6: Type 1 Diabetes Therapeutics Market, France, Revenue ($m), 2005-2010 19

Figure 7: Type 1 Diabetes Therapeutics Market, France, Forecast ($m), 2010-2018 20

Figure 8: Type 1 Diabetes Therapeutics Market, Germany, Revenue ($m), 2005-2010 21

Figure 9: Type 1 Diabetes Therapeutics Market, Germany, Forecast ($m), 2010-2018 22

Figure 10: Type 1 Diabetes Therapeutics Market, Italy, Revenue ($m), 2005-2010 23

Figure 11: Type 1 Diabetes Therapeutics Market, Italy, Forecast ($m), 2010-2018 24

Figure 12: Type 1 Diabetes Therapeutics Market, Spain, Revenue ($m), 2005-2010 25

Figure 13: Type 1 Diabetes Therapeutics Market, Spain, Forecast ($m), 2010-2018 26

Figure 14: Type 1 Diabetes Therapeutics Market, The UK, Revenue ($m), 2005-2010 27

Figure 15: Type 1 Diabetes Therapeutics Market, The UK, Forecast ($m), 2010-2018 28

Figure 16: Type 1 Diabetes Therapeutics Market, Japan, Revenue ($m), 2005-2010 29

Figure 17: Type 1 Diabetes Therapeutics Market, Japan, Forecasts ($m), 2010-2018 30

Figure 18: Opportunity and Unmet Need in the Type 1 Diabetes Therapeutics Market 33

Figure 19: Type 1 Diabetes Therapeutics - Strategic Competitor Assessment, 2011 35

Figure 20: Type 1 Diabetes Therapeutics - Pipeline by Phase of Development, 2011 47

Figure 21: Type 1 Diabetes Therapeutics - Technology Trends Analytics Framework, 2011 51

Figure 22: Type 1 Diabetes Therapeutics - Pipeline by Mechanism of Action, 2011 52

Figure 23: Type 1 Diabetes Therapeutics - Clinical Trials by Country, 2011 61

Figure 24: Type 1 Diabetes Therapeutics - Clinical Trials by Phase, 2011 62

Figure 25: Type 1 Diabetes Therapeutics - Clinical Trials by Status, 2011 63

Figure 26: Type 1 Diabetes Therapeutics - Overall Sponsors, 2011 64

Figure 27: Type 1 Diabetes Therapeutics - Prominent Sponsors, 2011 65

Figure 28: Type 1 Diabetes Therapeutics - Top Companies Participating in Therapeutics Clinical Trials, 2011 66

Figure 29: Type 1 Diabetes Therapeutics Market, Drivers and Barriers, 2011 67

Figure 30: Implications for Future Market Competition in the Type 1 Diabetes Market, 2011 68

Figure 31: Type 1 Diabetes Therapeutics Market - Pipeline by Company, 2011 69

Figure 32: GlobalData Market Forecasting Model 100

Companies Mentioned

BioDelivery Sciences International, Inc

Diamyd Medical AB

Evotec Aktiengesellschaft

GlaxoSmithKline plc

Generex Biotechnology Corporation

Halozyme Therapeutics, Inc.

MacroGenics, Inc.

MannKind Corporation

Novo Nordisk A/S

To order this report:

Pathology Industry: Type 1 Diabetes Therapeutics - Pipeline Assessment and Market Forecasts to 2018

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Nicolas Bombourg
Reportlinker
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Intl: +1 805-652-2626

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