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Volta Labs lance un processus automatisé de capture par hybridation Twist sur Callisto
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Volta Labs, a genomics applications company, is transforming the way biological research and analyses are performed with a cutting-edge digital fluidics platform to maximize performance and scalability of sample preparation.

News provided by

Volta Labs Inc.

Oct 09, 2025, 13:31 ET

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BOSTON, 9 octobre 2025 /PRNewswire/ -- Volta Labs, pionnier des solutions de préparation d'échantillons pour le séquençage de nouvelle génération (NGS), a annoncé aujourd'hui le lancement de l'application de capture par hybridation pour le kit Twist Standard Hybridization v2 sur Callisto.

La méthode, développée conjointement par Twist Bioscience et Volta, intègre la chimie de capture par hybridation de pointe de Twist à la plateforme Callisto entièrement automatisée de Volta. Cette collaboration permet aux chercheurs et aux laboratoires cliniques d'obtenir des performances d'enrichissement très cohérentes dans le cadre d'un processus simplifié.

« En associant le kit v2 éprouvé de Twist à l'architecture unique de Callisto pour une automatisation précise à température contrôlée, nous avons rationalisé le processus de capture d'hybrides, offrant un enrichissement uniforme et constant dans une solution simple, fiable et facile à utiliser par tous les laboratoires », a déclaré Udayan Umapathi, PDG de Volta Labs.

Avantages de Callisto pour la capture d'hybrides

La capture par hybridation représente l'une des approches essentielles pour les applications de séquençage ciblé, en particulier lorsque de grands panels sont utilisés ou lorsque la découverte de nouveaux variants est importante. Notre plateforme Callisto automatise cette étape critique. Traditionnellement, ces processus nécessitaient beaucoup de travail et l'expertise de techniciens de laboratoire spécialisés.

L'architecture unique de Callisto permet une manipulation précise des billes magnétiques associée à un contrôle ininterrompu et uniforme de la température pendant le processus de capture d'hybrides. Cela garantit des performances d'enrichissement constantes et élimine la variabilité qui caractérise les méthodes manuelles ou semi-automatiques.

Avec Callisto, cette partie du processus de capture d'hybrides est simple, fiable et entièrement automatisée. Ses performances constantes en matière d'enrichissement des cibles réduisent la nécessité de répéter les essais, ce qui permet aux laboratoires de réduire les coûts de séquençage tout en garantissant une couverture uniforme sur un large éventail de panels.

Avantages du kit Twist Standard Hybridization v2

Grâce à sa plateforme en silicium et à sa capacité à synthétiser l'ADN à grande échelle, Twist est en mesure de développer des outils NGS très uniformes. Le kit Standard Hybridization v2 de Twist offre aux chercheurs une couverture uniforme et une sensibilité élevée pour leurs régions d'intérêt.

« Nous avons conçu nos outils NGS Twist pour permettre à nos clients d'accélérer leurs recherches et de réduire les coûts de séquençage en aval », a déclaré Emily M. Leproust, PDG et cofondatrice de Twist Bioscience. « En associant notre kit Twist Standard Hybridization v2 à la plateforme automatisée de Callisto, nous rationalisons les flux de travail des clients et leur permettons d'atteindre des performances et une efficacité exceptionnelles. »

Pour plus de détails, visitez la page Twist Hybrid Capture App sur le site Web de Volta Labs : https://www.voltalabs.com/apps/hybridization-capture-for-twist-standard-v2

À propos de Volta Labs

Volta Labs est une société d'applications génomiques qui a développé une plateforme fluidique numérique de pointe pour maximiser les performances et l'évolutivité de la préparation des échantillons en génomique tout en assurant une cohérence inégalée. Pour plus d'informations sur nos produits et services, veuillez consulter le site www.voltalabs.com

Relations avec la presse :

Nicole Ellis Ovadia

Directeur du marketing stratégique
[email protected]

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