World Market for Continuous Manufacturing for Biologics and Small Molecules 2020-2030

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Sep 14, 2020, 06:30 ET

DUBLIN, Sept. 14, 2020 /PRNewswire/ -- The "Continuous Manufacturing Market (Small Molecules and Biologics), 2020 - 2030" report has been added to ResearchAndMarkets.com's offering.

Recent advances in manufacturing technologies have prompted pharmaceutical companies to shift from the traditional multi-step, batch manufacturing processes to faster, and relatively more efficient continuous manufacturing. Continuous manufacturing, also known as continuous flow chemistry, is an advanced manufacturing technology, which drives operations in a continuous manner (247) in one facility, without hold times. The concept was first described in the 1700s, in relation to the production of pig iron in blast furnaces. Since then, the technique has been used in various industries, including automotive, food and beverage, oil refining, chemicals, pulp and paper, electronics, metal smelting, steel making, and waste-water treatment industries. In recent years, continuous manufacturing is becoming popular within the biopharmaceutical industry as well, having captured the attention of many big pharma players, as well as leading contract manufacturing organizations (CMOs). The key benefits associated with the adoption of continuous manufacturing technology include reduction in manufacturing cost (by 15-30%), reduction in manpower (by 50-70%), less product deviation (by 50%), smaller footprint requirement (by 50-70%), reduction in power consumption (by 40%) and faster scale up. Specifically for biologics, continuous manufacturing, through upstream perfusion, is already a well-established field; this can be justified by the fact that, till now, more than 20 biologics manufactured based on this approach have been approved by the FDA. On the other hand, for oral solid dosage (OSD) forms and small molecules, continuous processing technology presents a versatile and beneficial manufacturing approach.

There are several technology providers/equipment suppliers, offering the necessary technologies and equipment for continuous manufacturing, such as continuous flow reactors (plug flow reactors, continuous stirred tank reactors (CSTR) and microreactors), continuous granulators, continuous coaters, continuous mixers/blenders, continuous chromatography equipment, continuous dryers and process analytical technologies (PAT). In addition, many companies have made heavy investments in order to install this technology and expand their facilities and capabilities in this regard. Moreover, innovators engaged in this field have received significant support in the form of grants from various administering institutes and incentives from key regulatory agencies as well. Despite the challenges associated with the adoption of this technology (such as cost of equipment, process development restrictions, manufacturing of a new facility and maintenance of the equipment), we believe that the opportunity for both technology developers and manufacturers/users engaged in this domain is likely to grow in the foreseen future. In fact, the ongoing COVID-19 crisis is expected to accelerate the industry's shift towards advanced manufacturing platforms including continuous manufacturing.

The report features an extensive study of the current market landscape and future opportunities for companies with capabilities in continuous manufacturing (both innovator companies with in-house expertise and contract manufacturers). It features an in-depth analysis, highlighting the capabilities of various stakeholders engaged in this domain.

Key Topics Covered:

1. PREFACE

2. EXECUTIVE SUMMARY

3. INTRODUCTION

4. MARKET LANDSCAPE

5. COMPANIES WITH EXPERTISE IN CONTINUOUS MANUFACTURING IN NORTH AMERICA: PROFILES

6. COMPANIES WITH EXPERTISE IN CONTINUOUS MANUFACTURING IN EUROPE: PROFILES

7. COMPANIES WITH EXPERTISE IN CONTINUOUS MANUFACTURING IN ASIA-PACIFIC: PROFILES

8. RECENT PARTNERSHIPS AND COLLABORATIONS

9. RECENT EXPANSIONS

10. CAPACITY ANALYSIS

11. ACADEMIC GRANT ANALYSIS

12. PATENT ANALYSIS

13. INITIATIVES OF COMPANIES WITH IN-HOUSE CONTINUOUS MANUFACTURING CAPABILITIES

14. CASE STUDY: MODULAR FACILITIES IN PHARMACEUTICAL/BIOTECHNOLOGY INDUSTRY

15. CASE STUDY: TECHNOLOGY AND EQUIPMENT PROVIDERS

16. CASE STUDY: ROADMAP FOR THE ADOPTION OF CONTINUOUS MANUFACTURING PROCESSES

17. MARKET FORECAST AND OPPORTUNITY ANALYSIS

18. CONCLUSION

19. EXECUTIVE INSIGHT

Companies Mentioned

3P Biopharmaceuticals
Abbott
AbbVie
ABN Cleanroom Technology
AC Immune
Acasti Pharma
ADC Biotechnology
ADDvise Group
ADMARES
AES Clean Technology
Aether
Airgas
Ajinomoto
Albian Group
Alconbury Weston
AMPAC Fine chemicals
AMRI
Angelini Pharma
Angstrom Technology
Arcinova
AstraZeneca
Asymchem
Clestra Cleanroom
Filtration Technology
Flowid
FlowRHEX
KinetiChem
Kingspan
Knowles Group
Konkuk University
KORSCH
L.B. Bohle Maschinen+ Verfahren
Lasco Services
Microflow CVO
Microinnova
Microzone Corporation
Modular Cleanrooms
ModWave
MRC Systems
MTX Contracts
Munson Machinery
Novasep
Nuvonis Technologies
OCTANORM
PaxVax
Pentec Health
Pfizer
PharmaBlock Sciences
Pharmadule Morimatsu
Plascore
Porsche Consulting
PortaFab
Porta-King Building Systems
Precision Cleanrooms
Precision NanoSystems
Skender
Snapdragon Chemistry
Shelving + Rack Systems
Starrco
STEELife
Stefatos
Sterling Pharma
Stodec Products
Stragen Pharma
Strike Bio
Synthelia Organics
Syrris
Ted Thorsen Material Handling
Telstar Life Science Solutions
Weaver Technologies
WH Partnership
Windmill Cardiovascular Systems
Wuxi AppTec
Xytel
YMC Process Technologies

For more information about this report visit https://www.researchandmarkets.com/r/b1jyzg

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