COVINGTON, Ky., May 13, 2020 /PRNewswire/ -- Bexion Pharmaceuticals announced today that the following three abstracts submitted to the 2020 American Society of Clinical Oncology (ASCO) have been accepted for oral or poster presentation:
Oral Presentation Tolerability and preliminary efficacy of BXQ-350 for refractory solid tumors and high-grade gliomas: First-in-human, first-in-class phase I trial.
Session: Developmental Therapeutics—Molecularly Targeted Agents and Tumor Biology Author(s): Olivier Rixe, John C. Morris, Robert Wesolowski, Emrullah Yilmaz, Richard Curry, Trisha M. Wise-Draper, Vinay K. Puduvalli Abstract: 3505
Poster Presentation A pediatric and young adult phase I dose escalation study of BXQ-350 for solid and central nervous system tumors.
Session: Central Nervous System Tumors Author(s): Mohamed Abdelbaki, Bhuvana Setty, Mariko D. DeWire, Timothy P. Cripe, Richard Curry Abstract: 2541 Poster: 32
Poster Presentation BXQ-350 to target to the lysosome and kill glioblastoma (GBM) cells via activation of apoptotic caspases in vitro.
Session: Developmental Therapeutics—Molecularly Targeted Agents and Tumor Biology Author(s): Laura Felix, Timothy J. Stephens, Nikhil J. Wilkins Abstract: 3639 Poster: 369
ASCO 2020 will be a virtual meeting held Friday, May 29 through Sunday, May 31.
The abstracts will be available on the ASCO website on May 13, 2020 at 5:00 p.m. ET. All posters, including poster discussions, will be available on the meeting website beginning Friday, May 29 at 8:00 am ET.
About Bexion Pharmaceuticals Bexion Pharmaceuticals is a clinical-stage biopharmaceutical company developing BXQ-350, a first-in-class agent composed of the multifunctional, lysosomal activator protein Saposin C and phosphatidylserine. BXQ-350 has demonstrated pre-clinical antitumor effects in vitro and in vivo, particularly in brain and other solid tumors, including those that may lead to brain metastases. Bexion has completed a multi-site first-in-human Phase 1 clinical trial of BXQ-350 for solid tumors and gliomas. A Phase 1 Pediatric Trial enrollment was completed in late 2019.
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