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El probiótico S. boulardii de Angel Yeast alivia los síntomas comunes de la EII
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Angel Yeast

Feb 09, 2022, 14:44 ET

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- El probiótico patentado S. boulardii de Angel Yeast alivia los síntomas comunes de la EII, según muestra una nueva investigación

YICHANG, China, 9 de febrero de 2022 /PRNewswire/ -- Angel Yeast Co., Ltd ("Angel Yeast"), un fabricante global de levadura y extracto de levadura, se asoció con la Universidad de Ciencia y Tecnología de Huazhong para realizar un estudio clínico que investigó la relación entre Saccharomyces boulardii Bld-3 (S. boulardii) y la enfermedad inflamatoria intestinal (EII). Los resultados del estudio muestran que el probiótico patentado a base de levadura desarrollado por Angel Yeast desempeña un papel beneficioso en el tratamiento de los síntomas de la EII.

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Research shows that Angel Yeast's patented probiotic S. boulardii alleviates common IBD symptoms.
Research shows that Angel Yeast's patented probiotic S. boulardii alleviates common IBD symptoms.

Los datos de la Fundación Internacional para los Trastornos Gastrointestinales (IFGD) revelan que la EII es el trastorno gastrointestinal funcional más común y afecta entre el 10 y el 15% de la población mundial.[1] Los tratamientos médicos típicos para la EII incluyen anticuerpos, esteroides e inmunomoduladores; sin embargo, estos tienen una eficacia baja y una alta incidencia de recurrencia.[2] Como resultado, existe una necesidad apremiante de terapias de salud innovadoras para ayudar a los pacientes a controlar y tratar la afección. S. boulardii fue desarrollado por Angel Yeast para abordar los problemas de diarrea, uno de los síntomas más comunes de la EII,[3] y mejorar la salud digestiva en general.

Antes del estudio conjunto, hubo una investigación mínima que examinó los efectos de las moléculas derivadas de S. boulardii y S. boulardii en la microbiota intestinal en la inflamación intestinal. Durante mucho tiempo se ha reconocido que la microbiota intestinal desempeña un papel fundamental en el mantenimiento de la salud de su huésped, con datos clínicos que demuestran que la microbiota intestinal de los pacientes con EII varía considerablemente en composición y función.[4]

Angel Yeast se asoció con la Universidad de Ciencia y Tecnología de Huazhong para explorar los mecanismos subyacentes involucrados en la prevalencia de la EII e identificar la relación científica entre S. boulardii y la EII. El dúo examinó el papel del probiótico en el ecosistema microbiano intestinal e identificó los posibles mecanismos de su actividad antiinflamatoria intestinal.

En el estudio, [5] los organismos modelo poblados con microbiota humana sintética recibieron una dieta del suplemento probiótico S. boulardii durante un total de 16 días, antes de recibir el tratamiento DSS para estimular la colitis. Los resultados encontraron que alimentar a los sujetos con S.boulardii alivió significativamente el daño de la mucosa en el tejido del colon, alteró la composición de la microbiota intestinal y el fenotipo metabólico fecal, y aumentó el desarrollo de ácidos grasos de cadena corta de metabolitos microbianos. Estos hallazgos apuntan hacia el potencial del probiótico para mejorar la regulación de las respuestas inflamatorias y disminuir la colitis inducida por DSS, y confirman que S. boulardii tiene el potencial de modular la microbiota intestinal para prevenir y tratar con éxito la EII. Los hallazgos se publicaron en la revista Food & Function en noviembre de 2021.

Empresas de todo el mundo han implementado el probiótico patentado S. boulardii de Angel Yeast en suplementos para la salud para cubrir las necesidades de los consumidores en busca de un ingrediente nutricional que apoye la salud inmunológica general, la buena digestión y un intestino feliz y saludable. Ahora, tras los nuevos hallazgos del estudio clínico, S. boulardii ha demostrado aún más su potencial para tratar la EII y apoyar a quienes la padecen mediante la prevención y el tratamiento de sus síntomas.

Lanzado en septiembre de 2021, el probiótico S. boulardii de Angel Yeast se desarrolla utilizando un proceso de lecho fluidizado a baja temperatura y una tecnología de protección única que forma rápidamente una capa de levadura densa para encerrar los probióticos de levadura activos atrapados en su interior. Esto fortalece la resistencia de la levadura al ácido gástrico y las sales biliares, lo que permite su uso como ingrediente para una amplia gama de suplementos dietéticos probióticos, como polvos, tabletas, cápsulas, bloques de yogur y chocolate.

Fuentes: 

[1] International Foundation for Gastrointestinal Disorders (IFFGD).Statistics. 

[2] Hvas CL et al., 2018. Current, Experimental, and Future Treatments in Inflammatory Bowel Disease: A Clinical Review, Immunopharmacology and Immunotoxicology, 40, 446-460. 

[3] World Gastroenterology Organisation Global Guidelines., 2015. Inflammatory Bowel Disease. 

[4] Lee T et al., 2017.Oral Versus Intravenous Iron Replacement Therapy Distinctly Alters the Gut Microbiota and Metabolome in Patients with Ibd, Gut, 66, 863-871.

[5] Li B et al., 2021. Saccharomyces boulardii alleviates DSS-induced intestinal barrier dysfunction and inflammation in humanized mice. Food & Function.

 

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