Global Alzheimer Disease Markets to 2030: Drug Discovery, markets, Regulatory Aspects, Competitive Landscape, Clinical Features, Epidemiology and Pathology

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Dec 01, 2021, 09:15 ET

DUBLIN, Dec. 1, 2021 /PRNewswire/ -- The "Alzheimer Disease - New Drugs, Markets and Companies" report from Jain PharmaBiotech has been added to ResearchAndMarkets.com's offering.

Alzheimer's disease remains a challenge in management. With nearly 8 million sufferers from this condition in the seven major markets of the world and anticipated increases in the future.

Alzheimer's disease market in the seven major markets is analyzed for the year 2020. Several new therapies are expected to be in the market and the shares of various types of approaches are estimated for the future up to the year 2030. As a background to the markets, pharmacoeconomic aspects of care of Alzheimer's disease patients and patterns of practice are reviewed in the seven major markets.

Profiles of 117 companies involved in developing diagnostics and therapeutics for Alzheimer's disease are presented along with 89 collaborations. The bibliography contains over 900 publications that are cited in the report.

Considerable research is in progress to understand the pathomechanism of the disease and find a cure. The only drugs approved currently are acetylcholinesterase inhibitors but they do not correct the basic pathology of the disease, beta amyloid deposits and neurofibrillary tangles. Several new approaches emphasize neuroprotection as well.

Early diagnosis of Alzheimer's disease is an important first step in management. Several biomarkers in cerebrospinal fluid, blood and urine can detect the disease. They provide a valuable aid to the clinical examination and neuropsychological testing which are the main diagnostic methods supplemented by brain imaging. Genotyping, particularly of ApoE gene alleles is also useful in the evaluation of cases and planning management.

The current management of Alzheimer's disease is reviewed and it involves a multidisciplinary approach. Acetylcholinesterase inhibitors are mostly asymptomatic treatment but some claims are made about a neuroprotective effect. Currently, the only approved neuroprotective therapy is memantine.

Management of these patients also requires neuroleptics for aggressive behavior and antidepressants. There is an emphasis on early detection at the stage of mild cognitive impairment and the early institution of neuroprotective measures. The value of mental exercise in delaying the onset of Alzheimer's disease is being recognized.

Research in Alzheimer's disease still aims at elucidating the basic pathomechanisms. Animal models are important for research, particularly in testing some of the potential therapeutic approaches. There is considerable research in progress at the various centers, some of which are funded by the National Institute of Aging of the National Institutes of Health.

Over 300 different compounds are at various stages of development for the treatment of Alzheimer's disease. These are classified and described. There are non-pharmacological approaches such as vagal nerve stimulation and cerebrospinal fluid shunting, which are in clinical trials. Ongoing as well as discontinued clinical trials of AD are tabulated.

Markets & Finances of AD Care

Introduction
Pharmacoeconomics of treatment of AD
Quality of Life in relation to the economics of AD
Costs associated with Alzheimer disease
Pharmacoeconomics of donepezil
Pharmacoeconomics studies using rivastigmine
Pharmacoenonomics studies using galantamine
Pharmacoenonomics studies using memantine
Epidemiology of AD
Patterns of AD care in major markets
Care of AD patients in the US
Cost of care
Medicare and AD
Patterns of practice in AD care
Opinions of physicians' organizations on drugs for dementia
Care of AD patients in the UK
Cost of care
Patterns of practice in AD care
NICE recommendations to NHS
Care of AD patients in Germany
Care of AD patients in France
Care of AD patients in Italy
Care of AD patients in Spain
Care of AD patients in Japan
Markets for AD diagnostics
Markets for AD therapeutics
Geographical markets for AD
Markets for currently approved drugs for AD
Markets for generic AD drugs
Statins
Future growth of AD market
Limitations of AD drug development by the biotechnology industry
Unmet needs in the management of AD
Drivers of AD markets
Increase of the aged populations
Increase in the number of approved drugs for AD
Limitations of the current therapies
Improvements in diagnosis
Increasing awareness of the disease
Support for AD research

Key Topics Covered:

Part I: Pathogenesis and Therapeutics

Executive Summary

1. Clinical Features, Epidemiology and Pathology

2. Diagnostic Procedures for Alzheimer Disease

3. Management of Alzheimer Disease

4. Research in Alzheimer Disease

5. Drug Discovery & Development for Alzheimer Disease

6. Innovative approaches to Alzheimer disease

7. Future and Regulatory Aspects of Alzheimer disease

Part II: Markets & Companies

8. Markets & Finances of AD Care

9. Companies

10. References

For more information about this report visit https://www.researchandmarkets.com/r/ed9bko

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