RIFM Human Health Articles on Fragrance Ingredients Are Among Most Cited in Elsevier Peer-Reviewed Scientific Journals and on BioMedLib

WOODCLIFF LAKE, N.J., March 10, 2011 /PRNewswire-USNewswire/ -- Peer review is an essential part of scientific publication. These top cited RIFM articles were recognized in 2010 by scientific publishing giant Elsevier. The citation of RIFM's articles by the scientific community validates RIFM's methodology.

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Dermal sensitization quantitative risk assessment (QRA) for fragrance ingredients published in Regulatory Toxicology and Pharmacology, vol. 52, no.1, October 2008 was recognized in 2010 by Elsevier as one of the Top 10 most cited articles on Scopus for the years 2007-2008 even though it was published at the end of 2008. The article is part of a special issue of Regulatory Toxicology and Pharmacology that also contains 6 other manuscripts on the QRA. This new methodology is a major improvement over the former approach because it specifically addresses the elements of exposure-based risk assessment that are unique to the induction of dermal sensitization, while being consistent with the principles of general toxicology risk assessment. This QRA is now used to determine global fragrance industry product management practices (IFRA Standards) for fragrance ingredients that are potential dermal sensitizers. Recognition of the QRA publication represents recognition of the QRA approach by the scientific community.

Food and Chemical Toxicology recognized RIFM's consistently high quality papers in their announcement of their Top 10 Most Cited Articles from 2007 to 2010. Click here to see Elsevier's announcement.

#2 A toxicologic and dermatologic assessment of cyclic and non-cyclic terpene alcohols when used as fragrance ingredients, Belsito, D., et al.,  Food and Chemical Toxicology, Volume 46, Issue 11, Supplement 1, November 2008

#5 A toxicologic and dermatologic assessment of ionones when used as fragrance ingredients, Belsito, D., et al., Food and Chemical Toxicology, Volume 45, Issue 1, Supplement 1, 2007

#7 A toxicologic and dermatologic assessment of related esters and alcohols of cinnamic acid and cinnamyl alcohol when used as a fragrance ingredient, Belsito, D., et al., Food and Chemical Toxicology, Vol. 45, Issue 1, Supplement 1, 2007

In the period 2006-2009, RIFM had 4 Group Summaries in the Top 45 most highly cited publications in Food and Chemical Toxicology. The Terpene Alcohol Group was the #2 most cited, the Ionone Group #13, the Cinnamic Acid, Alcohols, Aldehydes Group #16 and the Salicylate Group #45. This is out of more than 1600 published in this time frame. To date RIFM has published a total of 10 Group Summaries and more than 200 Fragrance Material Reviews (FMRs) on individual fragrance ingredients.

On BioMedLib, RIFM had the top 7 of the top ten cited on these subjects. BioMedLib is the online search engine for the National Library of Medicine's Medline® database containing millions of biomedical articles.

9/18/2010 - From the Desk of: Tom Elder, Article Delivery Services www.BioMedLib.com, Email correspondence: [email protected]

Top 10 Articles Published in the Same Domain Since Your Publication

Api AM, et al: Evaluation of the developmental toxicity of alpha-methyl-3,4-methylene-dioxyhydrocinnamic aldehyde in rats. Int J Toxicol; 2006 Mar-Apr; 25(2):127-32

Politano VT, et al: Evaluation of the developmental toxicity of alpha-iso-methylionone …. Int J Toxicol; 2007 May-Jun; 26(3):271-6

Politano VT, et al: Evaluation of the developmental toxicity of 1-(1,2,3,4,5,6,7,8-octahydro-2,3,8,8-tetramethyl-2-naphthalenyl) ethanone (OTNE) ….. Int J Toxicol; 2009 May-Jun; 28(3):213-8

Politano VT, et al: Evaluation of the developmental toxicity of methyl dihydrojasmonate (MDJ) ….. Int J Toxicol; 2008; 27(3):295-300

Lapczynski A, et al: Evaluation of the developmental toxicity of acetyl cedrene. Int J Toxicol; 2006 Sep-Oct; 25(5):423-8

Politano VT, et al: Evaluation of the developmental toxicity of linalool ….. Int J Toxicol; 2008 Mar-Apr; 27(2):183-8

Politano VT, et al: Evaluation of the developmental toxicity of dihydromyrcenol ….. Int J Toxicol; 2009 Mar-Apr; 28(2):80-7

Kim JC, Shin et al: Evaluation of developmental toxicity of amitraz ….. Arch Environ Contam Toxicol; 2007 Jan; 52(1):137-44

Houpt JT, et al: Developmental toxicity of thiodiglycol ….. Int J Toxicol; 2007 Jul-Aug; 26(4):365-71

Ema M, et al: Evaluation of developmental toxicity of ultraviolet absorber 2-(3',5'-di-tert-butyl-2'-hydroxyphenyl)-5-chlorobenzotriazole ….. Drug Chem Toxicol; 2006; 29(2):215-25

RIFM is the international scientific authority for the safe use of fragrance materials. RIFM generates, evaluates and distributes scientific data on the safety assessment of fragrance raw materials found in personal and household care products. Through extensive research, testing and constant monitoring of all scientific literature available, RIFM maintains its Database as the most comprehensive source worldwide of physical-chemical, toxicological and eco-toxicological data associated with known fragrance and flavor materials. All of RIFM's scientific findings are evaluated by an independent Expert Panel — an international group of dermatologists, pathologists, toxicologists, respiratory, reproductive and environmental scientists. The Expert Panel evaluates the safety of fragrance ingredients under conditions of intended use and publishes their results in peer-reviewed scientific journals. The decisions of the Expert Panel regarding restrictions of use are also published in the IFRA Standards, publicly available from the International Fragrance Association (IFRA) web site at www.ifraorg.org. For more information about RIFM and its activities, visit www.rifm.org or e-mail [email protected].

SOURCE Research Institute for Fragrance Materials, Inc.