Sprout Pharmaceuticals' Addyi® (flibanserin) Named "Best Prescription for Low Libido" in the 2026 Oprah Daily Menopause O-wards

Recognition follows Addyi's newly expanded FDA approval to treat both premenopausal and postmenopausal women under age 65

RALEIGH, N.C., Jan. 29, 2026 /PRNewswire/ -- Sprout Pharmaceuticals today announced that Addyi® has been named "Best Prescription for Low Libido" in the 2026 Oprah Daily Menopause O-wards, one of the most trusted and influential honors a brand can receive. 

The Oprah Daily Menopause O-wards shine a light on products that meaningfully improve the lives of women in menopause and midlife. Addyi's recognition reflects its status as a treatment doctors trust and choose more than any other for Hypoactive Sexual Desire Disorder (HSDD), backed by a one-of-a-kind approach to treating low desire and robust clinical proof that earned FDA approval for women under age 65.

"This recognition matters because it finally puts sexual health where it belongs—at the center of the conversation on women's health and longevity," said Cindy Eckert, Founder and CEO of Sprout Pharmaceuticals. "For too long, women were told to downplay or dismiss changes in desire. Addyi shut down that narrative with clinical proof. Being honored by Oprah Daily reinforces what the science shows and what women deserve to hear: HSDD is common, it's treatable, and it warrants real medical attention."

The honor follows a pivotal moment for women's sexual health: in December 2025, the U.S. Food and Drug Administration expanded Addyi's approval from premenopausal women to include women with HSDD under 65 regardless of peri or post-menopausal status. This approval closed a long-standing gap in care and recognized Addyi's well-established safety and efficacy profile backed by more than a decade of clinical and real-world data.

Regarded as a powerful endorsement among consumers, clinicians, and cultural voices, the Oprah Daily Editor's Choice seal reflects a broader shift toward normalizing conversations about menopause, desire, and women's quality of life—topics long overlooked by medicine and media alike.

"Menopause does not end a woman's sexuality but too often, women are made to feel invisible or untreatable when desire changes. I see it every day in my practice," said Dr. Kelly Casperson, board-certified urologist, sexual health specialist, and bestselling author of The Menopause Moment. "When women are offered real treatment options, they get something priceless back: hope. Addyi gives clinicians a science-backed option for HSDD before or after menopause and opens the door to more honest, informed conversations about sexual health at midlife and beyond.'

Since its FDA approval in 2015, Addyi has remained the #1 prescribed treatment for HSDD*, shaping how women's sexual health is understood and treated across the lifespan. Sprout Pharmaceuticals continues to lead the charge for evidence-based care and long-overdue equity in women's health.

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About Sprout Pharmaceuticals

Sprout Pharmaceuticals is leading a revolution in women's health, pioneering innovative treatments that address long-overlooked needs. With the launch of Addyi, the first ever FDA-approved treatment for Hypoactive Sexual Desire Disorder (HSDD), Sprout helped shift the conversation around women's sexual wellness. The company remains committed to advancing science, expanding access, and advocating for the care women deserve.

About Addyi® (flibanserin)

Addyi is the first FDA-approved prescription medication for the treatment of hypoactive sexual desire disorder (HSDD), now including all women under 65. It is a non-hormonal, once-daily pill prescribed by more than 30,000 U.S. healthcare professionals. Addyi works on key neurotransmitters involved in sexual desire and responsiveness.

Addyi is broadly accessible and affordable for most patients: women with insurance typically pay just $40 annually, and for those paying cash, Addyi is available for $149 per month with free shipping through PHILRx mail-order pharmacy. Addyi is also available at more than 70,000 retail pharmacies nationwide, where patients can use a GoodRx coupon to lower out-of-pocket costs.

Patients should consult with their healthcare provider to determine whether Addyi is appropriate for them. Learn more or start a telehealth visit today at Addyi.com.

About Hypoactive Sexual Desire Disorder (HSDD)
Hypoactive Sexual Desire Disorder (HSDD), also known as frustrating low libido, is a persistent lack of sexual interest or desire. It is the most common form of sexual dysfunction in women, impacting an estimated 40% of women according to the Mayo Clinic.

INDICATION

ADDYI (flibanserin) is indicated for the treatment of women less than 65 years of age with acquired, generalized hypoactive sexual desire disorder (HSDD) as characterized by low sexual desire that causes marked distress or interpersonal difficulty and is not due to:

• A co-existing medical or psychiatric condition,
• Problems within the relationship, or
• The effects of a medication or other drug substance.

Acquired HSDD refers to HSDD that develops in a patient who previously had no problems with sexual desire. Generalized HSDD refers to HSDD that occurs regardless of the type of stimulation, situation, or partner.

Limitations of Use:

• ADDYI is not indicated in men.
• ADDYI is not indicated to enhance sexual performance.

IMPORTANT SAFETY INFORMATION

Contraindications

• Moderate or strong cytochrome P450 3A4 (CYP3A4) inhibitors
• Hepatic impairment
• Known hypersensitivity to ADDYI or any of its components. Reactions, including anaphylaxis, reactions consistent with angioedema, pruritus, and urticaria have been reported.

Warnings and Precautions

• Hypotension and Syncope Due to an Interaction with Alcohol:  See Boxed Warning for risks associated with alcohol consumption. After taking ADDYI at bedtime, advise patients to not use alcohol until the following day.
• Hypotension and Syncope with CYP3A4 Inhibitors:  See Boxed Warning and Contraindication about use with moderate or strong cytochrome P450 3A4. Concomitant use of multiple weak CYP3A4 inhibitors that may include herbal supplements (e.g., ginkgo, resveratrol) or non-prescription drugs (e.g., cimetidine) could also lead to clinically relevant increases in flibanserin concentrations that may increase the risk of hypotension and syncope.
• Central Nervous System (CNS) Depression (e.g., Somnolence, Sedation):  Can occur with ADDYI alone and is exacerbated by other CNS depressants. The risk of CNS depression is also increased if ADDYI is taken during waking hours. Patients should avoid activities requiring full alertness (e.g., operating machinery or driving) until at least six hours after each dose and until they know how ADDYI affects them.
• Hypotension and Syncope with ADDYI Alone:  The use of ADDYI - without other concomitant medications known to cause hypotension or syncope - can cause hypotension and syncope. The risk is increased if ADDYI is taken during waking hours or if higher than the recommend dose is taken.
• Syncope and Hypotension in Patients with Hepatic Impairment: Any degree of hepatic impairment significantly increases flibanserin concentrations, which can lead to hypotension and syncope. ADDYI is contraindicated in patients with hepatic impairment.
• Hypersensitivity Reactions: Reactions including anaphylaxis, reactions consistent with angioedema, pruritus, and urticaria have been reported with ADDYI. Immediately discontinue ADDYI and initiate appropriate treatment if hypersensitivity reaction occurs.

Drug Interactions

• Oral Contraceptives and Other Weak CYP3A4 Inhibitors: Increases flibanserin exposures and incidence of adverse reactions. 
• Strong CYP2C19 Inhibitors: Increases flibanserin exposure which may increase risk of hypotension, syncope, and CNS depression.
• CYP3A4 Inducers: Use of ADDYI not recommended, flibanserin concentrations substantially reduced.
• Digoxin: Increases digoxin concentrations, which may lead to digoxin toxicity. Increase monitoring of digoxin concentrations.

Most Common Adverse Reactions

• Most common adverse reactions (incidence ≥2%) are dizziness, somnolence, nausea, fatigue, insomnia, urinary tract infection, anxiety, sinusitis, constipation, and dry mouth.

See Full Prescribing Information and Medication Guide, including Boxed Warning regarding hypotension and syncope in certain settings at Addyi.com/pi.

SOURCE: Sprout Pharmaceuticals
* IQVIA Monthly Total Prescriptions Volume Data Comparing Addyi vs Vyleesi in the US. Sept 2022–Dec 2025