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      BioLife Solutions Reports Third Quarter 2025 Financial Results

      BioLife Solutions Logo (PRNewsfoto/BioLife Solutions, Inc.)

      News provided by

      BioLife Solutions, Inc.

      Nov 06, 2025, 16:03 ET

      Share this article

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      Cell Processing revenue of $25.4 million, up 33% over Q3 2024

      GAAP gross margin of 62%  and non-GAAP adjusted gross margin of 64%

      GAAP net income of $0.6 million and non-GAAP adjusted EBITDA of $7.8 million or 28% of revenue

      Raises 2025 full-year Cell Processing revenue guidance to $93.0 million - $94.0 million; Full-year total revenue guidance to $95.0 - $96.0 million, adjusted for the recent sale of its evo cold chain logistics subsidiary

      Conference call begins at 4:30 p.m. Eastern time today

      BOTHELL, Wash., Nov. 6, 2025 /PRNewswire/ -- BioLife Solutions, Inc. (Nasdaq: BLFS) ("BioLife" or the "Company"), a leading developer and supplier of cell processing tools and services for the cell and gene therapy ("CGT") market, announces financial results for the three and nine months ended September 30, 2025.

      Roderick de Greef, BioLife's Chairman and CEO, commented, "We delivered another strong quarter, with cell processing revenue up 33% year over year and our eighth consecutive quarter of sequential growth. Performance reflected healthy growth across our biopreservation media (BPM) franchise and our broader cell processing tools portfolio, led by continued momentum from commercial BPM customers. By aligning the organization around our core cell processing business, we are driving sustainable, high-quality growth and expanding profitability, achieving another quarter of adjusted EBITDA margin improvement both year over year and sequentially."

      "The divestiture of our evo cold chain logistics business in early October has reshaped BioLife into a leading pure-play cell processing company centered on our highest-value, recurring revenue franchises. This streamlined profile, solid financial position and market leading product portfolio provide a strong foundation for continued profitable growth and long-term value creation."

      Third Quarter 2025 Business Highlights

      • Our biopreservation media is utilized in approximately 250 ongoing commercially sponsored clinical trials in the U.S., representing a more than 70% market share. This includes over 30 Phase III trials, or nearly 80% of these late-stage trials. Our CellSeal vials and hPL products are used in over 35 clinical trials.
      • Our biopreservation media is embedded in 16 unique commercial CGTs as of September 30, 2025, with expectations that approvals for 10 additional products, geographic expansions, earlier lines of treatment, or new indications will occur over the next 12 months. Our CellSeal cryogenic vials and hPL products are embedded into four approved therapies.
      • On October 6, 2025, we completed the sale of evo, a previously wholly owned cold chain logistics subsidiary operated under SAVSU Cleo Technologies, LLC (formerly known as SAVSU Technologies, Inc.), for an aggregate sales price of $25.5 million in cash (subject to certain adjustments). The tables further in this release present key financial results quarterly through the year ended December 31, 2024 and quarterly through September 30, 2025 excluding evo to provide an estimate of our financial profile on a continuing operations basis.

      Third Quarter 2025 Financial Results

      BioLife Solutions is presenting various financial metrics under U.S. generally accepted accounting principles (GAAP) and as adjusted (non-GAAP). In addition, BioLife Solutions completed the divestitures of Global Cooling, Inc., SciSafe, and CBS in 2024, and is presenting its financial condition and operating results as discontinued operations for all periods presented within the Condensed Consolidated Balance Sheets and Condensed Consolidated Statements of Operations. The Condensed Consolidated Statements of Comprehensive Loss, Condensed Consolidated Statements of Shareholders' Equity, and Condensed Consolidated Statements of Cash Flows are presented on a consolidated basis for both continuing operations and discontinued operations. All amounts, percentages, and disclosures for all periods presented reflect only the continuing operations of the Company unless otherwise noted.

      REVENUE

      • Total revenue for the third quarter of 2025 was $28.1 million, an increase of $6.7 million, or 31%, from $21.4 million for the third quarter of 2024 and up $2.6 million, or 10%, from the second quarter of 2025.
        • Cell Processing revenue was $25.4 million, an increase of $6.3 million, or 33%, from the same period in 2024 and up $2.4 million, or 10%, from the second quarter of 2025. Growth was primarily due to strong demand from customers with commercially approved therapies. The quarter included approximately $1.3 million in biopreservation media revenue that was accelerated into Q3 2025 at a commercial customer's request.
        • evo and Thaw platform revenue was $2.7 million, an increase of $0.4 million, or 15%, from the same period in 2024 and up $0.2 million, or 10%, from the second quarter of 2025.
      • Total revenue for the nine months ended September 30, 2025 was $77.4 million, an increase of $17.9 million, or 30%, from $59.5 million for the same period in 2024.
        • Cell Processing platform revenue for the nine months ended September 30, 2025 was $69.9 million, an increase of $16.7 million, or 31%, from the same period in 2024. Growth was due to strong demand from customers with commercially approved therapies, as well as revenue from biopreservation media product that was originally expected to ship in Q4 2025, as mentioned above.
        • evo and Thaw platform revenue for the nine months ended September 30, 2025 was $7.5 million, an increase of $1.2 million, or 19%, from the same period in 2024.

      GROSS MARGIN

      • Gross margin (GAAP) for the third quarter of 2025 was 62% compared with 63% for the third quarter of 2024. Adjusted gross margin (non-GAAP) for the third quarter of 2025 was 64% compared with 67% for the third quarter of 2024. The decreases were due to an inventory reserve of approximately $0.6 million recorded during the third quarter, which represented approximately 2% of Q3 2025 revenue.
      • Gross margin (GAAP) for the nine months ended September 30, 2025 was 62% compared with 63% for the same period in 2024. Adjusted gross margin (non-GAAP) for the nine months ended September 30, 2025 was 65% compared with 67% for the same period in 2024. The decreases were due to the inventory reserve of approximately $0.6 million recorded during the third quarter of 2025 mentioned above, and to product mix.

      OPERATING LOSS

      • Operating loss (GAAP) for the third quarter of 2025 was $0.1 million compared with $0.4 million for the third quarter of 2024. Adjusted operating income (non-GAAP) for the third quarter of 2025 was $1.3 million compared with $0.2 million for the third quarter of 2024.
      • Operating loss (GAAP) for the nine months ended September 30, 2025 was $17.9 million compared with $5.0 million for the same period in 2024. Adjusted operating income (non-GAAP) for the nine months ended September 30, 2025 was $1.7 million compared with adjusted operating loss of $3.0 million for the same period in 2024.

      NET INCOME / (LOSS)

      • Net income (GAAP) for the third quarter of 2025 was $0.6 million compared with net loss (GAAP) of $0.5 million for the third quarter of 2024. Adjusted net income (non-GAAP) for the third quarter of 2025 was $2.0 million compared with $34 thousand for the third quarter of 2024.
      • Net loss (GAAP) for the nine months ended September 30, 2025 was $15.7 million compared with $9.2 million for the same period in 2024. Adjusted net income (non-GAAP) for the nine months ended September 30, 2025 was $4.2 million compared with adjusted net loss of $3.2 million for the same period in 2024.

      NET INCOME / (LOSS) PER SHARE

      • Net income per share (GAAP) for the third quarter of 2025 was $0.01 compared with net loss per share of $0.01 for the third quarter of 2024.
      • Net loss per share (GAAP) for the nine months ended September 30, 2025 was $0.33 compared with $0.20 for the same period in 2024.

      ADJUSTED EBITDA

      • Adjusted EBITDA, a non-GAAP measure, for the third quarter of 2025 was $7.8 million, or  28% of revenue, compared with $5.0 million, or 23% of revenue, for the third quarter of 2024. 
      • Adjusted EBITDA, a non-GAAP measure, for the nine months ended September 30, 2025 was $19.7 million, or  25% of revenue, compared with $11.6 million, or 19% of revenue, for the same period in 2024. 

      CASH, CASH EQUIVALENTS, AND MARKETABLE SECURITIES

      • Cash, cash equivalents, and marketable securities as of September 30, 2025, were $98.4 million.
        • The cash, cash equivalents, and marketable securities balance as of September 30, 2025 does not include any cash proceeds from the sale of evo in October 2025.

      (As a result of presenting amounts in millions, rounding differences may exist in the percentages above.)

      2025 Financial Guidance

      Following the sale of its evo cold chain logistics business in early October, BioLife Solutions is updating its 2025 revenue guidance.

      Total 2025 revenue guidance, adjusted for the sale of evo, is $95.0 million to $96.0 million, representing an increase of 27% - 29% when compared to 2024 continuing operations revenues on a like for like basis. This guidance is based on the following expectations:

      • Cell Processing platform revenue: Raised to $93.0 million to $94.0 million from prior guidance of $91.0 million to $93.0 million, representing year-over-year growth of 26% to 28%.
      • Removal of approximately $8 million of evo-related revenue.

      Going forward, BioLife will report revenue as a single line item encompassing its entire product portfolio.

      Management continues to expect 2025 gross margin (GAAP) in the low-60% range and adjusted gross margin (non-GAAP) in the mid-60% range, as well as a reduction in net loss (GAAP) and continued expansion of adjusted EBITDA margin (non-GAAP), both compared with 2024.

      Conference Call & Webcast

      Management will discuss the Company's financial results, provide a general business update and answer questions during a conference call and live webcast today at 4:30 p.m. ET (1:30 p.m. PT).

      To access the webcast, log onto the Investor Relations page of the BioLife Solutions website at https://www.biolifesolutions.com/earnings. In addition, the conference call will be accessible by dialing toll-free 1-833-630-0431 or 1-412-317-1808 for international callers. A webcast replay will be available approximately two hours after the call ends and will be archived on https://www.biolifesolutions.com for 90 days.

      About BioLife Solutions

      BioLife is a leading developer and supplier of cell processing tools and services for the CGT market. Our expertise facilitates the commercialization of new therapies by supplying solutions that maintain the health and function of biologic materials during the collection, development, manufacturing and distribution. For more information, please visit www.biolifesolutions.com, and follow BioLife on LinkedIn and X.

      Cautions Regarding Forward Looking Statements

      Certain statements contained in this press release are not historical facts and may be forward-looking statements within the meaning of the Private Securities Litigation Reform Act of 1995. Words such as "plans," "intend," "expects," "continue," "believes," "anticipates," "designed," and similar words are intended to identify forward-looking statements. Forward-looking statements are based on our current expectations and beliefs, and involve a number of risks and uncertainties that are difficult to predict and that could cause actual results to differ materially from those stated or implied by the forward-looking statements. A description of certain of these risks, uncertainties and other matters can be found in filings we make with the U.S. Securities and Exchange Commission, all of which are available at www.sec.gov. Because forward-looking statements involve risks and uncertainties, actual results and events may differ materially from results and events currently expected by us. Readers are cautioned not to place undue reliance on these forward-looking statements, which speak only as of the date hereof. We undertake no obligation to publicly update these forward-looking statements to reflect events or circumstances that occur after the date hereof or to reflect any change in its expectations with regard to these forward-looking statements or the occurrence of unanticipated events.

      Non-GAAP Measures of Financial Performance

      To supplement our financial statements, which are presented on the basis of U.S. generally accepted accounting principles (GAAP), the following non-GAAP measures of financial performance are included on a consolidated basis in this release: adjusted gross margin, adjusted operating expenses, adjusted operating income/(loss), adjusted net income/(loss), earnings before interest, taxes, depreciation and amortization (EBITDA), and adjusted EBITDA. A reconciliation of GAAP to adjusted non-GAAP financial measures is included as an attachment to this press release.

      We believe these non-GAAP financial measures are useful to investors in assessing our operating performance. We use these financial measures internally to evaluate our operating performance and for planning and forecasting of future periods. We also believe it is in the best interests of investors to provide this non-GAAP information.

      While we believe these non-GAAP financial measures provide useful supplemental information to investors, there are limitations associated with the use of these non-GAAP financial measures. These non-GAAP financial measures may not be reported by competitors, and they may not be directly comparable to similarly titled measures of other companies due to differences in calculation methodologies. The non-GAAP financial measures are not an alternative to GAAP information and are not meant to be considered in isolation or as a substitute for comparable GAAP financial measures. They should be used only as a supplement to GAAP information and should be considered only in conjunction with our consolidated financial statements prepared in accordance with GAAP.

      Media & Investor Relations

      At the Company

      Troy Wichterman
      Chief Financial Officer
      (425) 402-1400
      [email protected]

      Investors

      Alliance Advisors IR
      Jody Cain
      (310) 691-7100
      [email protected]

      BIOLIFE SOLUTIONS, INC.
      CONDENSED CONSOLIDATED STATEMENTS OF OPERATIONS
      (Unaudited, amounts in thousands, except share and per share amounts)



      Three Months Ended
      September 30,


      Nine Months Ended
      September 30,

      (In thousands, except per share and share data)

      2025


      2024


      2025


      2024









      Product revenue

      $               26,250


      $               19,928


      $               72,258


      $               54,783

      Service revenue

      26


      20


      122


      119

      Rental revenue

      1,791


      1,443


      5,049


      4,637

      Total product, rental, and service revenue

      28,067


      21,391


      77,429


      59,539

      Costs and operating expenses:








      Cost of product, rental, and service revenue (exclusive of Intangible asset
      amortization)

      10,146


      7,400


      27,288


      20,100

      General and administrative

      12,074


      9,326


      34,970


      29,041

      Sales and marketing

      2,528


      2,507


      7,857


      7,366

      Research and development

      2,709


      1,893


      7,633


      5,997

      IPR&D expense

      —


      —


      15,521


      —

      Intangible asset amortization

      699


      683


      2,109


      2,054

      Total operating expenses

      28,156


      21,809


      95,378


      64,558

      Operating loss

      (89)


      (418)


      (17,949)


      (5,019)









      Other income (expense):








      Change in fair value of equity investments

      —


      —


      —


      (4,074)

      Interest income (expense), net

      508


      (230)


      1,873


      (695)

      Other income

      284


      97


      633


      496

      Total other income (expense), net

      792


      (133)


      2,506


      (4,273)









      Income (loss) before income tax (expense) benefit

      703


      (551)


      (15,443)


      (9,292)

      Income tax (expense) benefit

      (82)


      80


      (222)


      62

      Net income (loss) from continuing operations

      $                    621


      $                  (471)


      $             (15,665)


      $               (9,230)









      Discontinued operations:








      Loss from discontinued operations before income tax expense

      —


      (1,180)


      —


      (23,247)

      Income tax expense

      —


      (52)


      —


      (166)

      Loss from discontinued operations

      $                      —


      $               (1,232)


      $                      —


      $             (23,413)









      Net income (loss)

      $                    621


      $               (1,703)


      $             (15,665)


      $             (32,643)









      Net income (loss) per share - Basic:








      Continuing operations

      $                   0.01


      $                 (0.01)


      $                 (0.33)


      $                 (0.20)

      Discontinued operations

      $                      —


      $                 (0.03)


      $                      —


      $                 (0.51)

      Net income (loss) per share

      $                   0.01


      $                 (0.04)


      $                 (0.33)


      $                 (0.71)









      Net income (loss) per share - Diluted:








      Continuing operations

      $                   0.01


      $                 (0.01)


      $                 (0.33)


      $                 (0.20)

      Discontinued operations

      $                      —


      $                 (0.03)


      $                      —


      $                 (0.51)

      Net income (loss) per share per share

      $                   0.01


      $                 (0.04)


      $                 (0.33)


      $                 (0.71)









      Weighted average shares used to compute income (loss) per share:








      Basic

      47,925,038


      46,175,345


      47,622,196


      45,871,715

      Diluted

      48,723,535


      46,175,345


      47,622,196


      45,871,715

      BIOLIFE SOLUTIONS, INC.
      CONDENSED CONSOLIDATED STATEMENTS OF COMPREHENSIVE INCOME (LOSS)
      (Unaudited, amounts in thousands)



      Three Months Ended

      September 30,


      Nine Months Ended

      September 30,

      (In thousands)

      2025


      2024


      2025


      2024

      Net income (loss)

      $          621


      $      (1,703)


      $    (15,665)


      $    (32,643)

      Other comprehensive income

      59


      347


      106


      137

      Comprehensive income (loss)

      $          680


      $      (1,356)


      $    (15,559)


      $    (32,506)

      BIOLIFE SOLUTIONS, INC.
      CONDENSED CONSOLIDATED BALANCE SHEET INFORMATION
      (Unaudited, amounts in thousands)



      September
      30,


      December 31,

      (In thousands)

      2025


      2024

      Cash, cash equivalents, and marketable securities

      $          98,398


      $        109,212

      Working capital

      99,420


      116,027

      Current assets

      126,566


      148,761

      Total assets

      392,081


      399,487

      Current liabilities

      27,146


      32,734

      Long-term obligations

      11,196


      17,844

      Accumulated deficit

      (350,766)


      (335,101)

      Total shareholders' equity

      $        353,739


      $        348,909

      BIOLIFE SOLUTIONS, INC.
      CONDENSED CONSOLIDATED STATEMENT OF CASH FLOWS INFORMATION
      (Unaudited, amounts in thousands)



      Nine Months Ended
      September 30,

      (In thousands)

      2025


      2024

      Net cash provided by operating activities

      $         15,199


      $           6,786

      Net cash used in investing activities

      (72,676)


      (15,337)

      Net cash used in financing activities

      (8,428)


      (2,697)

      Effects of currency translation

      —


      (29)

      Net decrease in cash and cash equivalents

      $       (65,905)


      $       (11,277)





      Cash and cash equivalents – beginning of period

      $         95,386


      $         35,438

      Cash and cash equivalents – end of period

      29,481


      24,161





      Marketable securities

      68,917


      15,095





      Total cash, cash equivalents, and marketable securities

      $         98,398


      $         39,256

      BIOLIFE SOLUTIONS, INC.
      RECONCILIATION OF GAAP GROSS PROFIT TO NON-GAAP ADJUSTED GROSS MARGIN
      (Unaudited, amounts in thousands)



      Three Months Ended
      September 30,


      Nine Months Ended
      September 30,

      (In thousands)

      2025


      2024


      2025


      2024

      Total revenues

      $     28,067


      $     21,391


      $     77,429


      $     59,539

      Cost of revenues

      (10,146)


      (7,400)


      (27,288)


      (20,100)

      COGS intangible asset amortization

      (596)


      (577)


      (1,794)


      (1,736)

      GROSS PROFIT

      $     17,325


      $     13,414


      $     48,347


      $     37,703

      GROSS MARGIN

      62 %


      63 %


      62 %


      63 %









      ADJUSTMENTS TO GROSS PROFIT:








      Inventory reserve costs

      —


      247


      —


      247

      Gain on disposal of assets

      —


      —


      (12)


      —

      Intangible asset amortization

      596


      577


      1,794


      1,736

      ADJUSTED GROSS PROFIT

      $     17,921


      $     14,238


      $     50,129


      $     39,686

      ADJUSTED GROSS MARGIN

      64 %


      67 %


      65 %


      67 %

      BIOLIFE SOLUTIONS, INC.
      RECONCILIATION OF GAAP OPERATING EXPENSES TO NON-GAAP ADJUSTED OPERATING EXPENSES
      (Unaudited, amounts in thousands)



      Three Months Ended
      September 30,


      Nine Months Ended
      September 30,

      (In thousands)

      2025


      2024


      2025


      2024

      OPERATING EXPENSES

      $        28,156


      $        21,809


      $        95,378


      $        64,558









      ADJUSTMENTS TO OPERATING
      EXPENSES








      Cost of product, rental, and service
      revenues

      (10,146)


      (7,400)


      (27,288)


      (20,100)

      Acquisition and divestiture costs(1)

      (367)


      (334)


      (1,308)


      (706)

      Severance costs

      (316)


      —


      (732)


      —

      IPR&D expense

      —


      —


      (15,521)


      —

      Intangible asset amortization

      (699)


      (683)


      (2,109)


      (2,054)

      Loss on disposal of assets

      —


      —


      10


      —

      Other income

      —


      679


      —


      979

      ADJUSTED OPERATING EXPENSES

      $        16,628


      $        14,071


      $        48,430


      $        42,677


      (1)

      During the six months ended June 2025, we incurred $0.5 million in transaction expenses resulting from the PanTHERA acquisition, which is recorded in IPR&D expense on our Condensed Consolidated Statement of Operations. We reclassified $0.1 million incurred and recorded in Q1-2025 to conform with this current presentation.

      BIOLIFE SOLUTIONS, INC.
      RECONCILIATION OF GAAP OPERATING LOSS TO NON-GAAP ADJUSTED OPERATING INCOME
      (Unaudited, amounts in thousands)



      Three Months Ended
      September 30,


      Nine Months Ended
      September 30,

      (In thousands)

      2025


      2024


      2025


      2024

      OPERATING LOSS

      $             (89)


      $           (418)


      $       (17,949)


      $        (5,019)









      ADJUSTMENTS TO OPERATING LOSS
















      Acquisition and divestiture costs(1)

      367


      334


      1,308


      706

      Severance costs

      316


      —


      732


      —

      IPR&D expense

      —


      —


      15,521


      —

      Intangible asset amortization

      699


      683


      2,109


      2,054

      Gain on disposal of assets

      —


      —


      (10)


      —

      Other income

      —


      (679)


      —


      (979)

      Inventory reserve costs

      —


      247


      —


      247

      ADJUSTED OPERATING INCOME

      $          1,293


      $             167


      $          1,711


      $        (2,991)


      (1)

      During the six months ended June 2025, we incurred $0.5 million in transaction expenses resulting from the PanTHERA acquisition, which is recorded in IPR&D expense on our Condensed Consolidated Statement of Operations. We reclassified $0.1 million incurred and recorded in Q1-2025 to conform with this current presentation.

      BIOLIFE SOLUTIONS, INC.
      RECONCILIATION OF GAAP NET INCOME / (LOSS) FROM CONTINUING OPERATIONS TO NON-
      GAAP ADJUSTED NET INCOME
      (Unaudited, amounts in thousands)



      Three Months Ended
      September 30,


      Nine Months Ended
      September 30,

      (In thousands)

      2025


      2024


      2025


      2024

      NET INCOME / (LOSS) FROM
      CONTINUING OPERATIONS

      $             621


      $           (471)


      $       (15,665)


      $        (9,230)









      ADJUSTMENTS TO NET INCOME /
      (LOSS) FROM CONTINUING
      OPERATIONS
















      Acquisition and divestiture costs(1)

      367


      334


      1,308


      706

      Severance costs

      316


      —


      732


      —

      IPR&D expense

      —


      —


      15,521


      —

      Intangible asset amortization

      699


      683


      2,109


      2,054

      Gain on disposal of assets

      —


      —


      (10)


      —

      Change in fair value of investments,
      inclusive of interest

      (41)


      —


      (41)


      4,074

      Income tax expense / (benefit)

      82


      (80)


      222


      (62)

      Other income

      —


      (679)


      —


      (979)

      Inventory reserve costs

      —


      247


      —


      247

      ADJUSTED NET INCOME

      $          2,044


      $              34


      $          4,176


      $        (3,190)


      (1)

      During the six months ended June 2025, we incurred $0.5 million in transaction expenses resulting from the PanTHERA acquisition, which is recorded in IPR&D expense on our Condensed Consolidated Statement of Operations. We reclassified $0.1 million incurred and recorded in Q1-2025 to conform with this current presentation.

      BIOLIFE SOLUTIONS, INC.
      RECONCILIATION OF GAAP NET INCOME / (LOSS) FROM CONTINUING OPERATIONS TO NON-
      GAAP ADJUSTED EBITDA
      (Unaudited, amounts in thousands)



      Three Months Ended
      September 30,


      Nine Months Ended
      September 30,

      (In thousands)

      2025


      2024


      2025


      2024

      NET INCOME / (LOSS) FROM
      CONTINUING OPERATIONS

      $          621


      $        (471)


      $    (15,665)


      $     (9,230)









      ADJUSTMENTS:








      Interest (income) expense, net

      (508)


      230


      (1,873)


      695

      Accretion of available-for-sale investments

      (235)


      (88)


      (540)


      (408)

      Income tax expense / (benefit)

      82


      (80)


      222


      (62)

      Depreciation

      636


      711


      1,992


      2,224

      Intangible asset amortization

      699


      683


      2,109


      2,054

      EBITDA

      $       1,295


      $          985


      $    (13,755)


      $     (4,727)









      OTHER ADJUSTMENTS:








      Share-based compensation (non-cash)

      5,895


      4,134


      15,897


      12,233

      Acquisition and divestiture costs(1)

      367


      334


      1,308


      706

      Severance costs

      316


      —


      732


      —

      IPR&D expense

      —


      —


      15,521


      —

      Gain on disposal of assets

      —


      —


      (10)


      —

      Change in fair value of investments,
      inclusive of interest

      (41)


      —


      (41)


      4,074

      Other income

      —


      (679)


      —


      (979)

      Inventory reserve costs

      —


      247


      —


      247

      ADJUSTED EBITDA

      $       7,832


      $       5,021


      $     19,652


      $     11,554

      % of Revenue

      28 %


      23 %


      25 %


      19 %


      (1)

      During the six months ended June 2025, we incurred $0.5 million in transaction expenses resulting from the PanTHERA acquisition, which is recorded in IPR&D expense on our Condensed Consolidated Statement of Operations. We reclassified $0.1 million incurred and recorded in Q1-2025 to conform with this current presentation.

      As stated above, we anticipate the divestiture of evo to qualify and be presented as Discontinued Operations in our Annual Report on Form 10-K for the year ended December 31, 2025. Below we are presenting key financial results by quarter for the year ended December 31, 2024 and quarter ended September 30, 2025 exclusive of evo to provide an estimate of our financial profile on a continuing operations basis. This includes the non-GAAP measures Adjusted Gross Margin and Adjusted EBITDA.

      We have not yet finalized the accounting for the divestiture of evo and therefore note that all results below are subject to a number of assumptions, and actual results may differ. We do not anticipate actual results to be materially different from those presented below.

      BIOLIFE SOLUTIONS, INC.
      CONDENSED CONSOLIDATED STATEMENTS OF OPERATIONS, EXCLUSIVE OF EVO
      (Unaudited, amounts in thousands)


      (In thousands)

      Q1 2024


      Q2 2024


      Q3 2024


      Q4 2024


      FY2024

      Total revenues

      $     16,485


      $     18,042


      $     19,405


      $     20,714


      $     74,646

      Cost of revenues

      4,961


      5,905


      5,888


      6,829


      23,583

      Gross profit

      11,524


      12,137


      13,517


      13,885


      51,063

      General and administrative

      10,623


      9,174


      9,355


      11,476


      40,628

      Sales and marketing

      2,180


      2,325


      2,340


      2,087


      8,932

      Research and development

      1,159


      1,243


      1,166


      1,183


      4,751

      Intangible asset amortization

      312


      307


      307


      307


      1,233

      Operating (loss) income

      (2,750)


      (912)


      349


      (1,168)


      (4,481)

      Other income (expense), net

      52


      (4,245)


      (129)


      (24)


      (4,346)

      (Loss) income before income taxes

      (2,698)


      (5,157)


      220


      (1,192)


      (8,827)

      Income tax (expense) benefit

      (17)


      (1)


      80


      (24)


      38

      (Loss) income from continuing
      operations, net of tax

      $      (2,715)


      $      (5,158)


      $          300


      $      (1,216)


      $      (8,789)

      (In thousands)

      Q1 2025


      Q2 2025


      Q3 2025


      YTD 2025

      Total revenues

      $          22,053


      $          23,438


      $          25,958


      $          71,449

      Cost of revenues

      6,995


      7,938


      9,130


      24,063

      Gross profit

      15,058


      15,500


      16,828


      47,386

      General and administrative

      11,481


      11,363


      12,049


      34,893

      Sales and marketing

      2,443


      2,577


      2,386


      7,406

      Research and development

      1,439


      1,965


      2,097


      5,501

      Intangible asset amortization

      325


      332


      325


      982

      IPR&D expense

      —


      15,521


      —


      15,521

      Operating (loss) income

      (630)


      (16,258)


      (29)


      (16,917)

      Other income, net

      784


      930


      791


      2,505

      Income (loss) before income taxes

      154


      (15,328)


      762


      (14,412)

      Income tax (expense) benefit

      (14)


      (126)


      (82)


      (222)

      Income (loss) from continuing
      operations, net of tax

      $               140


      $         (15,454)


      $               680


      $         (14,634)

      BIOLIFE SOLUTIONS, INC.
      RECONCILIATION OF GROSS PROFIT TO NON-GAAP ADJUSTED GROSS MARGIN, EXCLUSIVE OF
      EVO
      (Unaudited, amounts in thousands)


      (In thousands)

      Q1 2024


      Q2 2024


      Q3 2024


      Q4 2024


      FY2024

      Total revenues

      $   16,485


      $   18,042


      $   19,405


      $   20,714


      $   74,646

      Cost of revenues

      (4,961)


      (5,905)


      (5,888)


      (6,829)


      (23,583)

      COGS intangible asset
      amortization

      (246)


      (241)


      (241)


      (241)


      (969)

      Gross profit

      $   11,278


      $   11,896


      $   13,276


      $   13,644


      $   50,094

      Gross margin

      68 %


      66 %


      68 %


      66 %


      67 %











      ADJUSTMENTS TO GROSS
      PROFIT:










      Inventory reserve costs

      —


      —


      247


      —


      247

      Gain on disposal of assets

      —


      —


      —


      87


      87

      Intangible asset amortization

      246


      241


      241


      241


      969

      ADJUSTED GROSS PROFIT

      $   11,524


      $   12,137


      $   13,764


      $   13,972


      $   51,397

      ADJUSTED GROSS MARGIN

      70 %


      67 %


      71 %


      67 %


      69 %

      (In thousands)

      Q1 2025


      Q2 2025


      Q3 2025


      YTD 2025

      Total revenues

      $        22,053


      $        23,438


      $        25,958


      $        71,449

      Cost of revenues

      (6,995)


      (7,938)


      (9,130)


      (24,063)

      COGS intangible asset
      amortization

      (259)


      (267)


      (259)


      (785)

      Gross profit

      $        14,799


      $        15,233


      $        16,569


      $        46,601

      Gross margin

      67 %


      65 %


      64 %


      65 %









      ADJUSTMENTS TO GROSS
      PROFIT:








      Gain on disposal of assets

      (12)


      —


      —


      (12)

      Intangible asset amortization

      259


      267


      259


      785

      ADJUSTED GROSS PROFIT

      $        15,046


      $        15,500


      $        16,828


      $        47,374

      ADJUSTED GROSS MARGIN

      68 %


      66 %


      65 %


      66 %

      BIOLIFE SOLUTIONS, INC.
      RECONCILIATION OF (LOSS) INCOME, EXCLUSIVE OF EVO, TO NON-GAAP ADJUSTED EBITDA
      EXCLUSIVE OF EVO
      (Unaudited, amounts in thousands)


      (In thousands)

      Q1 2024


      Q2 2024


      Q3 2024


      Q4 2024


      FY2024

      Income (loss) from continuing
      operations

      $   (2,715)


      $   (5,158)


      $       300


      $   (1,216)


      $   (8,789)











      ADJUSTMENTS:










      Interest expense, net

      200


      316


      226


      24


      766

      Accretion of available-for-sale investments

      (183)


      (137)


      (88)


      (68)


      (476)

      Income tax expense (benefit)

      17


      1


      (80)


      24


      (38)

      Depreciation

      172


      159


      151


      161


      643

      Intangible asset amortization

      312


      307


      307


      307


      1,233

      EBITDA

      $   (2,197)


      $   (4,512)


      $       816


      $      (768)


      $   (6,661)











      OTHER ADJUSTMENTS:










      Share-based compensation (non-
      cash)

      3,886


      3,730


      3,918


      3,748


      15,282

      Acquisition and divestiture costs

      237


      134


      334


      540


      1,245

      (Gain) loss on disposal of assets

      —


      —


      —


      129


      129

      Change in fair value of
      investments

      —


      4,074


      —


      —


      4,074

      Other income

      —


      (300)


      (679)


      —


      (979)

      Inventory reserve costs

      —


      —


      247


      —


      247

      ADJUSTED EBITDA FROM
      CONTINUING OPERATIONS

      $     1,926


      $     3,126


      $     4,636


      $     3,649


      $   13,337

      % of Revenue

      12 %


      17 %


      24 %


      18 %


      18 %

      (In thousands)

      Q1 2025


      Q2 2025


      Q3 2025


      YTD 2025

      Income (loss) from continuing
      operations

      $           140


      $     (15,454)


      $           680


      $     (14,634)









      ADJUSTMENTS:








      Interest income, net

      (683)


      (684)


      (508)


      (1,875)

      Accretion of available-for-sale investments

      (105)


      (200)


      (235)


      (540)

      Income tax expense (benefit)

      14


      126


      82


      222

      Depreciation

      185


      200


      203


      588

      Intangible asset amortization

      325


      332


      325


      982

      EBITDA

      $         (124)


      $     (15,680)


      $           547


      $     (15,257)









      OTHER ADJUSTMENTS:








      Share-based compensation (non-
      cash)

      3,982


      5,707


      5,779


      15,468

      Acquisition and divestiture costs

      1,001


      (59)


      367


      1,309

      Severance costs

      416


      —


      316


      732

      IPR&D expense

      —


      15,521


      —


      15,521

      (Gain) loss on disposal of assets

      (10)


      —


      —


      (10)

      Change in fair value of
      investments, inclusive of interest

      —


      —


      (41)


      (41)

      ADJUSTED EBITDA FROM
      CONTINUING OPERATIONS

      $        5,265


      $        5,489


      $        6,968


      $      17,722

      % of Revenue

      24 %


      23 %


      27 %


      25 %

      SOURCE BioLife Solutions, Inc.

      Modal title

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