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Displaying Results 51-75 of 152 "'PIK'"

May 29, 2026, 17:06 ET Die Menarini Group präsentiert auf der Jahrestagung 2026 der American Society of Clinical Oncology (ASCO) neue Daten aus der Phase-1b/2-Studie ELEVATE zu Elacestrant in Kombination mit Capivasertib bei Patientinnen mit ER-positivem, HER2-negativem metastasiertem Brustkrebs (mBC)

gleichzeitig ESR1- und PIK3CA-Mutationen auf. Die mediane Ansprechdauer (mDOR) ist noch nicht erreicht. Das vorläufige mPFS betrug 11,3 Monate in der gesamten RP2D-Population und 10,9 Monate bei Patienten mit gleichzeitig vorhandenen ESR1- und PIK3CA-Mutationen. Darüber hinaus zeigen diese

More news about: Menarini Industrie Farmaceutiche Riunite


May 29, 2026, 11:40 ET Le Groupe Menarini présente de nouvelles données de l'étude ELEVATE sur l'association de l'élacestrant et du capivasertib

gènes ESR1 et PIK3CA. La durée médiane de la réponse (mDOR) n'a pas encore été atteinte. La mPFS préliminaire était de 11,3 mois dans l'ensemble de la population RP2D, et de 10,9 mois chez les patients présentant des mutations coexistantes des gènes ESR1 et PIK3CA. En outre, ces premiers

More news about: Menarini Industrie Farmaceutiche Riunite


May 29, 2026, 10:13 ET 메나리니 그룹, 2026 미국임상종양학회(ASCO) 연례회의에서 ER+, HER2- 전이성 유방암(mBC) 환자를 대상으로 엘라세스트란트와 카피바서팁 병용요법을 평가한 1b/2상 ELEVATE 시험 신규 데이터 발표

질병 조절률(DCR) 88.9%, 24주 임상적 혜택률(CBR24) 66.7%, 객관적 반응률(ORR) 33.3%로 나타났다. ORR을 보인 모든 환자는 ESR1 및 PIK3CA 공존 돌연변이를 보유했다. 중위 반응 지속기간(mDOR)은 아직 도달하지 않았다. 예비 mPFS는 전체 RP2D 모집단에서 11.3개월, ESR1 및 PIK3CA 공존 돌연변이 환자에서 10.9개월이었다. 또한 이러한 초기 결과는 병용요법이 각 표적 요법과 표준 치료 내분비 요법의 알려진 안전성 프로필과 일치한다는 점을 보여준다.다나파버

More news about: Menarini Industrie Farmaceutiche Riunite


May 29, 2026, 05:23 ET Menarini Group presenta nuevos datos del estudio ELEVATE de elacestrant en combinación con capivasertib

coexistentes en ESR1 y PIK3CA. La mediana de duración de la respuesta (mDOR) aún no se ha alcanzado. La mediana de supervivencia libre de progresión (mPFS) preliminar fue de 11,3 meses en la población general de la RP2D y de 10,9 meses en pacientes con mutaciones coexistentes en ESR1 y PIK3CA. Además, estos resultados

More news about: Menarini Industrie Farmaceutiche Riunite


May 28, 2026, 12:46 ET Menarini Group Presents New Data from the Phase 1b/2 ELEVATE Study of Elacestrant in Combination with Capivasertib in Patients with ER+, HER2- Metastatic Breast Cancer (mBC) at the 2026 American Society of Clinical Oncology (ASCO) Annual Meeting

with ORR had co-existing ESR1 and PIK3CA mutations. The median duration of response (mDOR) has not yet been reached.  The preliminary mPFS was 11.3 months in the overall RP2D population, and 10.9 months in patients with co-existing ESR1 and PIK3CA mutations. Additionally, these initial

More news about: Menarini Industrie Farmaceutiche Riunite


May 21, 2026, 17:00 ET Lilly to showcase oncology portfolio across tumor types and treatment modalities at the 2026 American Society of Clinical Oncology Annual Meeting

next-generation phosphoinositide 3-kinase alpha (PI3Kα) inhibitor designed to selectively target tumors with PIK3CA mutations while sparing wild-type PI3Kα. Activating mutations in the PIK3CA gene (which encodes PI3Kα enzyme) are oncogenic drivers present in approximately 40% of hormone receptor

More news about: Eli Lilly and Company


May 20, 2026, 06:00 ET Discovery Life Sciences Launches IVDR-Compliant Luminos® Comprehensive with 7-to-10-Day Turnaround for EU Oncology Trials

actionable oncogenes, tumor suppressor genes, DNA damage repair pathways, and emerging therapeutic targets. Established biomarkers (EGFR, KRAS, BRAF, PIK3CA, HER2, TP53) sit alongside less-charted targets relevant to next-generation TKI and small-molecule programs, including KEAP1/NFE2L2, ATM/CHEK2, the

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May 15, 2026, 09:24 ET Elong Hotel Technology Perkuat Strategi "Eco-Going Global"

mulai dari pengadaan barang lintasnegara, pergudangan lokal, distribusi kamar, hingga PMS internasional.Elong Hotel (Jakarta PIK) yang berada di kawasan inti PIK menjadi contoh keberhasilan strategi tersebut. Pada 2025, hotel ini mencatat tingkat okupansi (occupancy rate/OCC) sebesar 93%

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May 11, 2026, 06:51 ET FS KKR Capital Corp. Announces First Quarter 2026 Results and Strategic Value Enhancement Actions; Declares Second Quarter 2026 Distribution of $0.42 per share

amended (the "HSR Act").  The Preferred Stock contains a current dividend rate of 5.00% per annum in cash, or, at the Company's option, 7.00% per annum in PIK dividends.  The Preferred Stock will rank junior to all existing indebtedness of the Company and senior to the Company's common stock.  The Preferred

More news about: Future Standard


May 06, 2026, 16:16 ET Blue Owl Technology Finance Corp. Announces March 31, 2026 Financial Results

143,358Payment-in-kind ("PIK") interest income24,057

More news about: Blue Owl Technology Finance Corp.


May 06, 2026, 16:15 ET Blue Owl Capital Corporation Announces March 31, 2026 Financial Results

$           356,463Payment-in-kind ("PIK") interest income

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May 06, 2026, 16:15 ET Albemarle Reports First Quarter 2026 Results

Other income, net - $9.8 million of income from PIK dividends of preferred equity in a Grace subsidiary and a $1.9 million gain primarily resulting from the adjustment of indemnification related to previously

More news about: Albemarle Corporation


May 05, 2026, 13:48 ET HTGC 2-WEEK DEADLINE ALERT: Hercules Capital (HTGC) Facing Securities Class Action After Allegations of Copying Google Ventures, Misstated Marks, and PIK Loans - Hagens Berman

according to Hunterbrook's analysis, a growing share of Hercules' income is "phantom" because of the company's increasing usage of payment-in-kind ("PIK") loans to enable its borrowers to pay interest by adding to the principal of their debt rather than paying interest on their debt.Hunterbrook

More news about: Hagens Berman Sobol Shapiro LLP


May 01, 2026, 16:15 ET Beasley Broadcast Group Announces Settlement of Previously Announced Exchange Offer and Tender Offer

Second Lien Notes participated in the Exchange Offer, exchanging their Existing Second Lien Notes into $98,475,254 aggregate principal amount of 2027 PIK Notes. On March 30, 2026, the Company completed the purchase of $15.9 million aggregate principal amount of Existing First Lien Notes pursuant

More news about: Beasley Media Group, Inc.


Apr 30, 2026, 09:00 ET HTGC Lawsuit Alleges Company Allegedly Copied Deal Sourcing Process - Hercules Capital Investors Face Losses Following Company Allegedly Copied Deal Sourcing Process-- Hagens Berman

according to Hunterbrook's analysis, a growing share of Hercules' income is "phantom" because of the company's increasing usage of payment-in-kind ("PIK") loans to enable its borrowers to pay interest by adding to the principal of their debt rather than paying interest on their debt.Hunterbrook

More news about: Hagens Berman Sobol Shapiro LLP


Apr 29, 2026, 08:00 ET Beasley Broadcast Group Announces Expiration of Exchange Offer, Tender Offer and Consent Solicitations and Receipt of Valid Consents from 100% of Outstanding Existing First Lien Noteholders to Proposed Amendments to Existing First Lien Notes Indenture and Acceptance of 99.53% of Outstanding Existing Second Lien Notes

"Existing Second Lien Noteholders") had the opportunity to exchange their holdings into newly issued 10.000% Senior Secured Second Lien PIK Notes due 2027 (the "2027 PIK Notes") at an exchange ratio of 50.0% of the aggregate principal amount (or $500 per $1,000 of principal amount) of the Existing

More news about: Beasley Media Group, Inc.


Apr 29, 2026, 06:03 ET 2026 Q2 State of Private Credit Benchmark Report: Heron Finance analyzes 73 of the largest private credit funds

borrowers."Key findings from the State of Private Credit Benchmark Report (Q2 2026 edition) include:PIK interest remains healthy: Payment-in-kind (PIK) interest marginally increased in Q4 2025, but generally remained in line with long-term historical averages.Non-accrual

More news about: Heron Finance


Apr 27, 2026, 18:17 ET Hercules Capital (HTGC) Under Fire: Class Action Filed After Allegations of Copying Google Ventures, Misstated Marks, and PIK Loans -- Hagens Berman

according to Hunterbrook's analysis, a growing share of Hercules' income is "phantom" because of the company's increasing usage of payment-in-kind ("PIK") loans to enable its borrowers to pay interest by adding to the principal of their debt rather than paying interest on their debt.Hunterbrook

More news about: Hagens Berman Sobol Shapiro LLP


Apr 23, 2026, 18:51 ET INVESTOR NOTICE: Hercules Capital (HTGC) Investors with Substantial Losses Have Opportunity to Lead Investor Class Action- Hagens Berman

according to Hunterbrook's analysis, a growing share of Hercules' income is "phantom" because of the company's increasing usage of payment-in-kind ("PIK") loans to enable its borrowers to pay interest by adding to the principal of their debt rather than paying interest on their debt.Hunterbrook

More news about: Hagens Berman Sobol Shapiro LLP


Apr 23, 2026, 07:00 ET Beasley Broadcast Group Extends Early Second Lien Tender Date, Exchange Offer Withdrawal Deadline, Tender Offer Expiration Date, First Lien Consent Solicitation Expiration Date, Exchange Offer Expiration Date, Tender Offer Settlement Date and the Exchange Offer Settlement Date of Previously Announced Exchange Offer and Tender Offer

offer to purchase nor a solicitation of an offer to purchase any Existing Notes or the Issuer's new 10.000% Senior Secured Second Lien PIK Notes due 2027 (the "2027 PIK Notes") in the Offers.Requests for the Exchange Offer Memorandum, the Supplements and other documents relating to the Offers

More news about: Beasley Media Group, Inc.


Apr 17, 2026, 08:17 ET Hercules Capital (HTGC) Under Fire: Class Action Filed After Allegations of Copying Google Ventures, Misstated Marks, and PIK Loans -- Hagens Berman

according to Hunterbrook's analysis, a growing share of Hercules' income is "phantom" because of the company's increasing usage of payment-in-kind ("PIK") loans to enable its borrowers to pay interest by adding to the principal of their debt rather than paying interest on their debt.Hunterbrook

More news about: Hagens Berman Sobol Shapiro LLP


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