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Dec 07, 2025, 16:30 ET Lilly's Jaypirca (pirtobrutinib) met its primary endpoint in first-of-its-kind, head-to-head Phase 3 study versus Imbruvica (ibrutinib)
with hematologic malignancies, patients aged ≥65 years experienced higher rates of Grade ≥3 ARs and serious ARs compared to patients <65 years of age.Renal Impairment: Because severe renal impairment increases pirtobrutinib exposure, reduce Jaypirca dose in these patients according to
More news about: Eli Lilly and Company
Dec 07, 2025, 09:30 ET Rigel Presents Updated Data from the Ongoing Phase 1b Study Evaluating R289 in Patients with Lower-Risk MDS at the 67th ASH Annual Meeting and Exposition
updated data as of October 28, 2025, include:33 patients were enrolled, representing a difficult-to-treat population. The median age was 75. The median number of prior therapies was 3 (range: 1-8); 76% (25) of patients had received luspatercept, 73% (24) had received an erythropoiesis
More news about: Rigel Pharmaceuticals, Inc.
Dec 07, 2025, 07:30 ET Studies Point to a Growing Role for New Therapies and Immunotherapies in Treating Blood Cancers
arm. Patients whose cancer had certain characteristics, including core binding factor fusions, FLT3 mutations, or NPM1 mutations (unless age 60 or over), were excluded from the trial. As a result, the study reflects a patient population of predominantly intermediate-to-high-risk AML, although
More news about: American Society of Hematology
Dec 07, 2025, 01:27 ET Texas Business Leader and Philanthropist Thomas O. Hicks Passes Away at Age 79
multimedia:https://www.prnewswire.com/news-releases/texas-business-leader-and-philanthropist-thomas-o-hicks-passes-away-at-age-79-302634724.htmlSOURCE
More news about: Hicks Holdings LLC
Dec 06, 2025, 22:40 ET Innovent Announces Inclusion of Seven Innovative Drugs including TYVYT New Indication and SYCUME in China's National Reimbursement Drug List
a RET gene fusion, 2) adult and pediatric patients 12 years of age and older with advanced or metastatic medullary thyroid cancer (MTC) with a RET mutation who require systemic therapy, and 3) adult and pediatric patients 12 years of age and older with advanced or metastatic thyroid cancer with a RET
More news about: Innovent Biologics
Dec 06, 2025, 12:28 ET Lundbeck announces positive Phase 2 long-term data for bexicaserin in rare childhood-onset epilepsies, at American Epilepsy Society (AES) Annual Meeting
Program). The FDA has granted Breakthrough Therapy designation for bexicaserin for the treatment of seizures associated with DEEs for patients two years of age and older. Bexicaserin has also recently been granted Breakthrough Therapy Designation in China for the treatment of seizures associated with DEEs.About
More news about: H. Lundbeck A/S
Dec 06, 2025, 12:25 ET Lundbeck announces positive Phase 2 long-term data for bexicaserin in rare childhood-onset epilepsies, at American Epilepsy Society (AES) Annual Meeting
Program). The FDA has granted Breakthrough Therapy designation for bexicaserin for the treatment of seizures associated with DEEs for patients two years of age and older. Bexicaserin has also recently been granted Breakthrough Therapy Designation in China for the treatment of seizures associated with DEEs.About
More news about: H. Lundbeck A/S
Dec 06, 2025, 11:43 ET Yidan Prize Foundation connects global insights and local expertise at annual flagship Summit
and 100 K–12 schools and networks, across two days. The first day of the Summit brought into focus critical topics, including: Staying human in the age of AI, defining the opportunities and challenges around edtech, how synergy and collaboration drive and sustain change, and cultivating leadership at
More news about: Yidan Prize Foundation
Dec 06, 2025, 09:20 ET Yidan Prize Foundation connects global insights and local expertise at annual flagship Summit
and 100 K–12 schools and networks, across two days. The first day of the Summit brought into focus critical topics, including: Staying human in the age of AI, defining the opportunities and challenges around edtech, how synergy and collaboration drive and sustain change, and cultivating leadership at
More news about: Yidan Prize Foundation
Dec 06, 2025, 08:30 ET Advances in Technology Help Improve Safety and Access to Blood Cancer Therapies
patients were enrolled in the study and received transplants with chemotherapy-based conditioning. Participants' age at the time of their initial B-ALL diagnosis ranged from 2 to 30 with a median age of 13.5 years. Half of the enrolled patients were male. When they received their transplant, half were on their
More news about: American Society of Hematology
Dec 06, 2025, 07:15 ET Studies Highlight Innovative Approaches to Improving Patient Care and Outcomes
common, but readily fixable problem."Women of child-bearing age are at high risk for iron deficiency. Menstruation and low intake of iron-rich foods are some of the most common causes of iron deficiency among women in this age group, Dr. Godby said. In addition, some commonly used medications,
More news about: American Society of Hematology
Dec 06, 2025, 07:00 ET Research Reveals Avenues for Informing and Improving Sickle Cell Care
only provide evidence that the gene therapy works in younger patients, but suggest it could be even more beneficial in this age group. "We think treating them at an earlier age may be better because you could potentially prevent some irreversible complications that lead to chronic issues," said Dr. Frangoul.Based
More news about: American Society of Hematology
Dec 05, 2025, 18:31 ET Children's Education Franchise COMPUCHILD Expands Further Into Santa Clara County, California
passionate about education and the transformative impact that early enrichment can have on children. "Introducing children to new ideas at an early age can completely change the way they see the world," said Ms. Mahalingam. "When I joined COMPUCHILD, I wanted to bring meaningful and relevant after-school
More news about: CompuChild
Dec 05, 2025, 16:20 ET Johnson & Johnson's INLEXZO™ (gemcitabine intravesical system) delivers 74 percent disease-free survival at one year in BCG-unresponsive, high-risk, papillary-only NMIBC
monotherapy in Cohort 2 of SunRISe-1, 72% were 65 years of age or older and 34% were 75 years or older. There were insufficient numbers of patients <65 years of age to determine if these patients respond differently to patients 65 years of age and older. Please read full
More news about: Johnson & Johnson
Dec 05, 2025, 15:24 ET Omni Consumer Products Welcomes 10-Foot RoboCop Statue to Detroit, Marking 20 Years of Artistic Defictionalization
installation)Installation Date - Wednesday, December 3, 2025Location - Eastern Market, 3434 Russell Street, Detroit, MI, adjacent to FREE AGE Production StudioStatue Specs - 10-foot-tall, 2.5-ton Bronze Statue (~3,500lb statue with ~1,600lb stainless steel base)Interactivity
More news about: Omni Consumer Products
Dec 05, 2025, 14:40 ET Frame It Easy Responds to a Colorless 2026 With a First-Ever Matboard Matching Breakthrough
customization to complement any print or space. And this isn't just a feature; it's a rebellion.As creativity risks flattening in the age of algorithms, Frame It Easy is doubling down on personalization, expression, and artistry. Instead of settling for sameness, the company invites creators,
More news about: Frame It Easy
Dec 05, 2025, 14:38 ET Elijah Craig Barrel Proof Rye Named Whisky Advocate's 2025 "Whisky of the Year"
established his distillery in 1789 on the banks of Elkhorn Creek in modern day Georgetown, Kentucky. He is credited with being the first distiller to age his wares in charred oak barrels. The clear, unaged corn liquor became transformed into a bold amber liquid with a distinctively smooth flavor that makes
More news about: Heaven Hill Brands
Dec 05, 2025, 12:59 ET 'I'D RATHER GET A ROOT CANAL': US WORKERS DREAD THE OFFICE HOLIDAY PARTY
World."Gen Z workers are the loneliest of all. Nearly half (45%) of workers aged 18-25 say they regularly feel lonely at work – far more than any other age group, according to a
More news about: Sunny
Dec 05, 2025, 12:46 ET Sobi to Showcase Scientific advances and Commitment to Haematology at ASH 2025
alfa)ALTUVOCT® (efanesoctocog alfa) is indicated for the treatment and prophylaxis of bleeding in patients with haemophilia A (HA). ALTUVOCT can be used for all age groups and any disease severity.About the Sobi and Sanofi CollaborationSobi and Sanofi collaborate on the development and commercialisation
More news about: Swedish Orphan Biovitrum AB
Dec 05, 2025, 12:00 ET Heartland Dental Announces Launch of the Orahh Care Dental Community
AARP AARP is the nation's largest nonprofit, nonpartisan organization dedicated to empowering people 50 and older to choose how they live as they age. With a nationwide presence, AARP strengthens communities and advocates for what matters most to the more than 125 million Americans 50-plus and their
More news about: Heartland Dental
Dec 05, 2025, 12:00 ET AAOS Establishes Orthobiologics Registry to Advance Evidence-Based Orthobiologics Research
and greater emphasis on staying active continues to drive demand for innovative orthobiologic treatment options. With over 18% of the population over age 55 experiencing symptomatic knee osteoarthritis3, the social and physical impact of this condition continues to be widespread.For more
More news about: American Academy of Orthopaedic Surgeons
Dec 05, 2025, 11:59 ET DUPR and USA Pickleball Announce Landmark Agreement to Adopt DUPR as Official Exclusive Rating System
technology platform, trusted by the world's leading clubs, tournaments, leagues, and players. DUPR's dynamic rating system unifies pickleball across age, gender, and location by analyzing match results to accurately evaluate all players across a 2.000 - 8.000 scale. DUPR is the official pickleball rating
More news about: DUPR
Dec 05, 2025, 09:15 ET The Jed Foundation Receives $40 Million Gift From MacKenzie Scott
2024 report by the Substance Abuse and Mental Health Services Administration, 2.6 million adolescents age 12 to 17 years (10.1%) had serious thoughts of suicide in the past year. Approximately 1.2 million (4.6 %) made a plan for suicide, and 700,000 (2.7%)
More news about: The Jed Foundation
Dec 05, 2025, 09:04 ET USMNT Stars Gio Reyna and Joe Scally Mentor International Soccer Academy Players at Borussia Mönchengladbach
standards that separate prospects from pros."I wish something like this existed when I was younger," said Reyna. "Being exposed to Europe at this age gives players opportunities that can change their careers. The talent level here is high — that's why it's great that you get to live here and experience
More news about: International Soccer Academy
Dec 05, 2025, 09:02 ET SUBARU: GEAR FOR GOOD INITIATIVE NAMES FIVE YOUTH SOCCER PROGRAM BENEFICIARIES TO HELP GROW THE GAME IN 2026
official rules) is open to legal U.S. residents at least 18 years of age who live within a 75-mile radius of
More news about: Subaru of America, Inc.