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Dec 08, 2025, 13:30 ET Menarini Group Presents Elacestrant (ORSERDU®) Phase 2 Combination Data in Patients with ER+, HER2- Metastatic Breast Cancer (mBC) at the 2025 San Antonio Breast Cancer Symposium
increased cholesterol (30%), increased AST (29%), increased triglycerides (27%), fatigue (26%), decreased hemoglobin (26%), vomiting (19%), increased ALT (17%), decreased sodium (16%), increased creatinine (16%), decreased appetite(15%), diarrhea(13%), headache (12%), constipation (12%), abdominal pain
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Dec 08, 2025, 10:13 ET Dr Pepper Marks 18 Years of Impact with the Announcement of the 2025 Dr Pepper Tuition Giveaway Winners
to Belmont University where she studied Music Business and is now the manager of an award-winning international country superstar and an independent alt/pop band. Jimenez is now completing his education at the University of North Carolina at Chapel Hill with plans to join a top marketing consulting firm
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Dec 08, 2025, 04:40 ET Ascletis' Oral Small Molecule GLP-1, ASC30, Demonstrated Placebo-Adjusted Weight Loss of 7.7% with Better Gastrointestinal Tolerability in Its 13-Week U.S. Phase II Study in Participants with Obesity or Overweight
vomiting observed with orforglipron titrated weekly. - No hepatic safety signal was observed, and no elevations of alanine transaminase (ALT), aspartate aminotransferase (AST) or total bilirubin (TBL) were observed.- Two conference calls/webcasts are scheduled to discuss
More news about: Ascletis Pharma Inc.
Dec 07, 2025, 16:30 ET Lilly's Jaypirca (pirtobrutinib) met its primary endpoint in first-of-its-kind, head-to-head Phase 3 study versus Imbruvica (ibrutinib)
AST increased (17; 1.6), pneumonia (16; 14), bruising (16; -), potassium decreased (13; 1.6), sodium decreased (13; -), lipase increased (12; 4.4), ALT increased (11; 1.6), potassium increased (11; 0.8), alkaline phosphatase increased (11; -). Grade 4 laboratory abnormalities in >5% of patients included
More news about: Eli Lilly and Company
Dec 07, 2025, 12:01 ET Data Published in the New England Journal of Medicine Confirm the Long-term Durability and Safety of HEMGENIX® (etranacogene dezaparvovec-drlb) Over Five Years
months post-infusion. Only five TRAEs were reported between years four and five. The most common adverse events were an increase in alanine transaminase (ALT), for which nine (16.7%) participants received supportive care with reactive corticosteroids for a mean duration of 81.4 days (standard deviation: 28.6;
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Dec 07, 2025, 09:30 ET Rigel Presents Updated Data from the Ongoing Phase 1b Study Evaluating R289 in Patients with Lower-Risk MDS at the 67th ASH Annual Meeting and Exposition
count decreased and pneumonia (each n=5, 15%), and alanine aminotransferase (ALT) increased and aspartate aminotransferase (AST) increased (each n=3, 9%). One (1) dose limiting toxicity (DLT) (Grade 4 AST increased/Grade 3 ALT increased) was reported in the 750 mg dose group.For evaluable transfusion
More news about: Rigel Pharmaceuticals, Inc.
Dec 06, 2025, 09:18 ET ALT5 Investor Alert: Hagens Berman Investigates ALT5 Sigma (ALTS) Over Auditor Resignation and Potentially False Financials
in ALT5 who suffered significant losses to contact the firm now."ALT5 Sigma
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Dec 05, 2025, 16:48 ET Au Québec : Janette Bertrand moderiert eine Sendung mit 100 Jahren!
„Jung und Alt, wir haben etwas gemeinsam. Wir werden selten angehört und selten verstanden. Deshalb schlage ich Ihnen vor, jungen Menschen zuzuhören, um zu versuchen,
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Dec 05, 2025, 16:20 ET Johnson & Johnson's INLEXZO™ (gemcitabine intravesical system) delivers 74 percent disease-free survival at one year in BCG-unresponsive, high-risk, papillary-only NMIBC
pain, decreased lymphocytes, hematuria, increased creatinine, increased potassium, increased AST, decreased sodium, bladder irritation, and increased ALT. USE IN SPECIFIC POPULATIONS Pregnancy There are no available data on the use of INLEXZO™ in pregnant women to inform
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Dec 03, 2025, 22:45 ET Le TECNO MEGABOOK K15S fait son entrée officielle sur le marché français avec des promotions pour le Black Friday
importantes. Les utilisateurs peuvent passer rapidement du mode Silencieux au mode Équilibré et au mode Performance à l'aide de la touche de raccourci Ctrl + Alt + T.Le MEGABOOK K15S est doté d'un châssis entièrement métallique, offrant une durabilité exceptionnelle et une sensation agréable. La conception
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Dec 03, 2025, 12:59 ET U.S. FDA approves expanded indication for Lilly's Jaypirca (pirtobrutinib), the first and only non-covalent (reversible) BTK inhibitor, for adults with relapsed or refractory CLL/SLL previously treated with a covalent BTK inhibitor
AST increased (17; 1.6), pneumonia (16; 14), bruising (16; -), potassium decreased (13; 1.6), sodium decreased (13; -), lipase increased (12; 4.4), ALT increased (11; 1.6), potassium increased (11; 0.8), alkaline phosphatase increased (11; -). Grade 4 laboratory abnormalities in >5% of patients included
More news about: Eli Lilly and Company
Dec 03, 2025, 08:38 ET Violife Recognized for Cultural Impact with Fast Company's Brands That Matter Award
[email protected]*Nielsen, U.S. Unit Share of Alt Cheese, latest 26 weeks, week ending 11/01/25. Violife® dairy free cheese: 35% in such category. U.S. Unit Share of Alt Cream Cheese, latest 26 weeks, week ending 11/01/25. Violife® dairy free cream cheese: 41.9%
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Dec 03, 2025, 07:30 ET ADC Therapeutics Announces Updated Data from LOTIS-7 Phase 1b Clinical Trial of ZYNLONTA® in Combination with Bispecific Antibody Supporting Potential Best-in-Class Regimen in Patients with Relapsed/Refractory Diffuse Large B-cell Lymphoma
observed in > 5% of patients included neutropenia (32.7%), GGT increased (16.3%), anemia (10.2%), WBC decreased (8.2%), generalized oedema (8.2%), ALT increased (8.2%), AST increased (6.1%), and thrombocytopenia (6.1%)Grade 5 AEs occurred in 2 (4.1%) patients; one was treatment-related per
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Dec 02, 2025, 07:29 ET Erste teilnehmende Phygital Stars für die Games of the Future 2025 in Abu Dhabi bekanntgegeben
Wolves.Beim Phygital Drone Racing werden Minchan Kim, Gewinner der FAI World Drone Racing Championship 2023, sowie Yuki Hashimoto, 18 Jahre alt und Goldmedaillengewinner bei den World Games in China, für das Team BDS an den Start gehen. Sie werden gegen die Tech Drone League antreten,
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Dec 01, 2025, 13:11 ET Anlässlich seines 100-jährigen Bestehens stellt Duas Rodas seine neue Marke DR Flavors & Ingredients vor und beginnt einen neuen Entwicklungszyklus
haben, bleiben unverändert."Rosemeri Francener unterstreicht das Verantwortungsbewusstsein, das mit diesem neuen Zyklus einhergeht. „100 Jahre alt zu werden, ist eine seltene Leistung. Aber mehr als das, es ist eine Verantwortung. Wir ehren unsere Geschichte, indem wir mit Fokus, Ziel und Leidenschaft
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Dec 01, 2025, 12:00 ET Citius Oncology Announces U.S. Commercial Launch of LYMPHIR™, a Novel Cancer Immunotherapy for Cutaneous T-Cell Lymphoma (CTCL)
medical management.HepatotoxicityLYMPHIR can cause hepatotoxicity. In the pooled safety population, elevated ALT occurred in 70% of patients, with Grade 3 ALT occurring in 22%; elevated AST occurred in 64% of patients, with Grade 3 AST elevation occurring in 9%. For Grade 3 events, median
More news about: Citius Oncology, Inc.
Dec 01, 2025, 08:38 ET Jazz Up the Holidays This December at Jimmy's Jazz & Blues Club
The Mallett Brothers – Sunday, December 28, 2026 at 7:30PM: Blending rock, Americana, and alt-country, The Mallett Brothers Band has become a fan-favorite for their raw energy and unforgettable live performances.
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Nov 26, 2025, 10:00 ET Koreanische Tempelküche: Eine weltweit anerkannte nachhaltige Esskultur
spezialisiert haben. Die Veranstaltung zog an zwei Tagen mehr als 20.000 Besucher an. Bemerkenswert ist, dass 47 % der Besucher zwischen 20 und 30 Jahre alt waren, was ein deutlicher Hinweis auf das wachsende Interesse der jüngeren Generation an einer nachhaltigen, pflanzlichen Esskultur ist.Im August
More news about: Cultural Corps of Korean Buddhism
Nov 26, 2025, 05:28 ET Il Gruppo Menarini annuncia che, al 67° Congresso Annuale dell'American Society of Hematology, presenterà nuovi dati su ELZONRIS® (tagraxofusp-erzs)
l'innalzamento dei livelli degli enzimi epatici, risultato reversibile dopo l'interruzione della dose.Monitorare l'alanina aminotransferasi (ALT) e l'aspartato aminotransferasi (AST) prima di ogni infusione con ELZONRIS. Sospendere temporaneamente la somministrazione di ELZONRIS in caso di aumento
More news about: Menarini Industrie Farmaceutiche Riunite
Nov 25, 2025, 19:10 ET Menarini Group、ELZONRIS®(タグラクソフスプ・エルツ)の新たなデータを第67回米国血液学会年次総会・学術展示会で発表
倍以上に上昇した場合は、ELZONRISの投与を一時的に中止し、正常化または消失した時点で投与を再開します。副反応最も一般的な副作用(発現率30%以上)は、毛細血管漏出症候群、悪心、倦怠感、発熱、末梢性浮腫、体重増加です。最も一般的な臨床検査値異常(発現率50%以上)は、アルブミン、血小板、ヘモグロビン、カルシウム、ナトリウムの減少、グルコース、ALT、ASTの増加です。 枠付き警告を含む完全な処方情報をご参照ください。疑われる副作用を報告する場合は、Stemline
More news about: Menarini Industrie Farmaceutiche Riunite
Nov 25, 2025, 08:36 ET Menarini Group 宣佈將於第 67 屆美國血液學會年會暨展覽會 (67th American Society of Hematology Annual Meeting and Exposition) 發表 ELZONRIS® (tagraxofusp-erzs) 最新數據
ELZONRIS 治療與肝臟酵素升高有關。在臨床試驗接受 ELZONRIS 治療病人中,79% (96/122) 病人出現 ALT 上升,而 76% (93/122) 病人出現 AST 上升。26% (32/122) 病人出現第 3 級 ALT 上升。30% (36/122) 病人出現第 3 級 AST 上升,而 3% (4/122) 病人出現第 4 級 AST 上升。大多數病人於第 1 週期出現肝酵素上升,但中止注射則可以逆轉。每次注射 ELZONRIS 前,量度谷丙轉氨酶 (ALT) 和谷草轉氨酶 (AST)。如果轉氨酶上升至正常上限 5 倍以上,則暫停 ELZONRIS 注射。轉氨酶恢復正常或緩解後,則恢復治療。不良反應最常見的不良反應為毛細血管滲漏症候群、噁心、疲倦、發燒、週邊水腫和體重增加,發生率≥
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Nov 25, 2025, 08:00 ET Citius Oncology to Exhibit at the 67th American Society of Hematology (ASH) Annual Meeting
medical management.HepatotoxicityLYMPHIR can cause hepatotoxicity. In the pooled safety population, elevated ALT occurred in 70% of patients, with Grade 3 ALT occurring in 22%; elevated AST occurred in 64% of patients, with Grade 3 AST elevation occurring in 9%. For Grade 3 events, median
More news about: Citius Oncology, Inc.
Nov 25, 2025, 05:07 ET Menarini Group anuncia nuevos datos sobre ELZONRIS ® (tagraxofusp-erzs) que se presentarán en la 67ª Reunión y Exposición Anual de la Sociedad Americana de Hematología
enzimas hepáticas. En pacientes que recibieron ELZONRIS en ensayos clínicos, se produjeron elevaciones de ALT en el 79 % (96/122) y elevaciones de AST en el 76 % (93/122). Se informaron elevaciones de ALT de grado 3 en el 26 % (32/122) de los pacientes. Se informaron elevaciones de AST de grado 3 en el 30 %
More news about: Menarini Industrie Farmaceutiche Riunite
Nov 25, 2025, 05:04 ET Menarini Group anuncia novos dados sobre ELZONRIS® (tagraxofusp-erzs) a serem apresentados na 67ª Reunião e Exposição Anual da Sociedade Americana de Hematologia
associado a elevações nas enzimas hepáticas. Em pacientes recebendo ELZONRIS em estudos clínicos, elevações na ALT ocorreram em 79% (96/122) e elevações na AST ocorreram em 76% (93/122). Elevações de ALT de grau 3 foram relatadas em 26% (32/122) dos pacientes. Elevações de AST de grau 3 foram relatadas em 30%
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Nov 25, 2025, 04:53 ET Menarini Group anuncia nuevos datos sobre ELZONRIS® (tagraxofusp-erzs)
enzimas hepáticas. En los pacientes que recibieron ELZONRIS en ensayos clínicos, se observaron elevaciones de ALT en el 79 % (96/122) y de AST en el 76 % (93/122). Se notificaron elevaciones de ALT de grado 3 en el 26 % (32/122) de los pacientes. Se notificaron elevaciones de AST de grado 3 en el 30 % (36/122)
More news about: Menarini Industrie Farmaceutiche Riunite