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Antibody Partnering Terms and Agreements


News provided by

Reportlinker

May 29, 2012, 06:15 ET

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NEW YORK, May 29, 2012 /PRNewswire/ -- Reportlinker.com announces that a new market research report is available in its catalogue:

Antibody Partnering Terms and Agreements

http://www.reportlinker.com/p0803164/Antibody-Partnering-Terms-and-Agreements.html#utm_source=prnewswire&utm_medium=pr&utm_campaign=Biopharmaceutical

Summary This report provides details of the latest antibody agreements announced in the healthcare sectors, covering:

Antibody-drug conjugates

Monoclonal antibodies

Murine mAb

Chimeric mAb

Humanized mAb

Human aAb

Polyclonal Antibodies

Trends in antibody partnering deals

Antibody partnering agreement structure

Antibody partnering contract documents

Top antibody deals by value

Most active antibody dealmakers

Description

The report provides a detailed understanding and analysis of how and why companies enter antibody partnering deals. The majority of deals are discovery or development stage whereby the licensee obtains a right or an option right to license the licensors antibody technology. These deals tend to be multicomponent, starting with collaborative R&D, and commercialization of outcomes.

This report provides details of the latest antibody agreements announced in the healthcare sectors, covering:

AntibodiesAntibody-drug conjugatesMonoclonal antibodiesMurine mAbChimeric mAbHumanized mAbHuman aAbPolyclonal Antibodies

Understanding the flexibility of a prospective partner's negotiated deals terms provides critical insight into the negotiation process in terms of what you can expect to achieve during the negotiation of terms. Whilst many smaller companies will be seeking details of the payments clauses, the devil is in the detail in terms of how payments are triggered – contract documents provide this insight where press releases do not.

This report contains over 1500 links to online copies of actual antibody deals and contract documents as submitted to the Securities Exchange Commission by companies and their partners. Contract documents provide the answers to numerous questions about a prospective partner's flexibility on a wide range of important issues, many of which will have a significant impact on each party's ability to derive value from the deal.

The initial chapters of this report provide an orientation of antibody dealmaking and business activities. Chapter 1 provides an introduction to the report, whilst chapter 2 provides an overview of the trends in antibody dealmaking since 2007, including details of average headline, upfront, milestone and royalty terms.

Chapter 3 provides a review of the leading antibody deals since 2007. Deals are listed by headline value, signed by bigpharma, most active bigpharma, and most active of all biopharma companies. Where the deal has an agreement contract published at the SEC a link provides online access to the contract.

Chapter 4 provides a comprehensive listing of the top 50 bigpharma companies with a brief summary followed by a comprehensive listing of antibody deals as well as contract documents available in the public domain. Where available, each deal title links via Weblink to an online version of the actual contract document, providing easy access to each contract document on demand.

Chapter 5 provides a comprehensive and detailed review of antibody partnering deals signed and announced since 2007, where a contract document is available in the public domain. The chapter is organized by company A-Z, stage of development at signing, deal type (collaborative R&D, co-promotion, licensing etc), and specific therapy focus. Each deal title links via Weblink to an online version of the deal record and where available, the contract document, providing easy access to each contract document on demand.

The report also includes numerous tables and figures that illustrate the trends and activities in antibody partnering and dealmaking since 2007.

In conclusion, this report provides everything a prospective dealmaker needs to know about partnering in the research, development and commercialization of antibody technologies and products.

Antibody Partnering Terms and Agreements is intended to provide the reader with an in-depth understanding and access to antibody trends and structure of deals entered into by leading companies worldwide.

Antibody Partnering Terms and Agreements includes:

Analysis of antibody deal structure

Access to headline, upfront, milestone and royalty data

Case studies of real-life antibody deals

Access to over 1500 antibody contract documents

The leading antibody deals by value since 2007

Most active antibody dealmakers since 2007

The leading antibody partnering resources

In Antibody Partnering Terms and Agreements, the available contracts are listed by:

Company A-Z

Headline value

Stage of development at signing

Deal component type

Specific therapy target

Specific antibody type

Each deal title links via weblink to an online version of the deal record and where available, the contract document, providing easy access to each contract document on demand.

The Antibody Partnering Terms and Agreements report provides comprehensive access to available deals and contract documents for over 1500 antibody deals. Analyzing actual contract agreements allows assessment of the following:

What are the precise antibody rights granted or optioned?

What is actually granted by the agreement to the partner company?

What exclusivity is granted?

What is the payment structure for the deal?

How are sales and payments audited?

What is the deal term?

How are the key terms of the agreement defined?

How are IPRs handled and owned?

Who is responsible for commercialization?

Who is responsible for development, supply, and manufacture?

How is confidentiality and publication managed?

How are disputes to be resolved?

Under what conditions can the deal be terminated?

What happens when there is a change of ownership?

What sublicensing and subcontracting provisions have been agreed?

Which boilerplate clauses does the company insist upon?

Which boilerplate clauses appear to differ from partner to partner or deal type to deal type?

Which jurisdiction does the company insist upon for agreement law?

Benefits

In-depth understanding of antibody deal trends since 2007Access to headline, upfront, milestone and royalty dataAnalysis of the structure of antibody agreements with numerous real life case studiesComprehensive access to over 1500 actual antibody deals entered into by the world's biopharma companiesDetailed access to actual antibody contracts enter into by the leading fifty bigpharma companiesInsight into the terms included in a antibody agreement, together with real world clause examplesUnderstand the key deal terms companies have agreed in previous dealsUndertake due diligence to assess suitability of your proposed deal terms for partner companies

Executive Summary Chapter 1 – Introduction Chapter 2 – Trends in antibody dealmaking

2.2. Antibody partnering over the years

2.3. Bigpharma antibody dealmaking activity

2.4. Bigpharma not active in antibody partnering

2.5. Antibody partnering by deal type

2.6. Antibody partnering by disease type

2.7. Partnering by antibody type

2.8. Average deal terms for antibody partnering

2.8.1 Antibody headline values

2.8.2 Antibody upfront payments

2.8.3 Antibody milestone payments

2.8.4 Antibody royalty rates

Chapter 3 – Leading antibody deals

3.2. Top antibody deals by value

3.3. Top antibody deals involving bigpharma

Chapter 4 – Bigpharma antibody deals

4.2. How to use bigpharma antibody partnering deals

4.3. Bigpharma antibody partnering company profiles

Abbott

Actavis

Alcon Labs

Allergan

Amgen

Apotex

Astellas

AstraZeneca

Baxter International

Bayer

Biogen Idec

Boehringer Ingelheim

Bristol-Myers Squibb

Celgene

Cephalon

Chugai

CSL

Daiichi Sankyo

Dainippon Sumitomo

Eisai

Eli Lilly

Forest Laboratories

Genzyme

Gilead Sciences

GlaxoSmithKline

Hospira

Kyowa Hakko Kirin

Lundbeck

Menarini

Merck & Co

Merck KGaA

Mitsubishi Tanabe

Mylan

Novartis

Novo Nordisk

Nycomed Pharma

Otsuka

Pfizer

Roche

Sanofi

Servier

Shionogi

Stada

Takeda

Teva

UCB

Warner Chilcott

Watson

Chapter 5 – Antibody dealmaking directory

5.2. Company A-Z

5.3. By stage of development

Discovery

Pre-clinical

Phase I

Phase II

Phase III

Registration

Marketed

5.4. By deal type

Asset purchase

Assignment

Bigpharma outlicensing

Co-development

Collaborative R&D

Co-market

Contract service

Co-promotion

CRADA

Cross-licensing

Development

Distribution E

Equity purchase

Evaluation

Grant

Joint venture

Licensing

Loan

Manufacturing

Marketing

Material transfer

Option

Promotion

Research

Royalty financing

Settlement

Spin out

Sub-license

Supply

Technology transfer

Termination

5.5. By therapy area

Cardiovascular

Central nervous system

Dermatology

Gastrointestinal

Genetic disorders

Genitourinary

Hematology

Hormonal disorders

Hospital care

Immunology

Infection

Inflammatory

Metabolic

Musculoskeletal

Oncology

Ophthalmics

Respiratory

5.6. By antibody technology type

Antibodies

Antibody-drug conjugate

Monoclonal antibodies

Chimeric mAb

Humanized mAb

Human mAb

Murine mAb

Polyclonal antibodies

Chapter 6 – Antibody partnering resource center

6.2. Antibody partnering events

6.3. Further reading on antibody dealmaking

Appendices

Appendix 2 – Example antibody partnering agreement

About Wildwood Ventures

Current Partnering

Current Agreements

Recent titles from CurrentPartnering

Order Form – Reports

Table of figures

Figure 2: Antibody partnering since 2007

Figure 3: Bigpharma – top 50 – antibody deals 2007 to 2011

Figure 4: Bigpharma antibody deal frequency – 2007 to 2011

Figure 5: Inactive bigpharma in antibody 2007-2011

Figure 6: Antibody partnering by deal type since 2007

Figure 7: Antibody partnering by disease type since 2007

Figure 8: Antibody partnering by oncology target since 2007

Figure 9: Antibody partnering by therapeutic antibody type since 2007

Figure 10: Antibody deals with a headline value

Figure 11: Antibody deal headline value distribution, US$million – discovery stage

Figure 12: Antibody deal headline value distribution, US$million – preclinical stage

Figure 13: Antibody deal headline value distribution, US$million – phase I stage

Figure 14: Antibody deal headline value distribution, US$million – phase II stage

Figure 15: Antibody deal headline value distribution, US$million – phase III stage

Figure 16: Antibody deal headline value distribution, US$million – regulatory stage

Figure 17: Antibody deal headline value distribution, US$million – marketed stage

Figure 18: Summary median headline value by stage of development, 2007-2011

Figure 19: Antibody deals with upfront payment values

Figure 20: Antibody deal upfront payment distribution, US$million – discovery stage

Figure 21: Antibody deal upfront payment distribution, US$million – preclinical stage

Figure 22: Antibody deal upfront payment distribution, US$million – phase I stage

Figure 23: Antibody deal upfront payment distribution, US$million – phase II stage

Figure 24: Antibody deal upfront payment distribution, US$million – phase III stage

Figure 25: Antibody deal upfront payment distribution, US$million – regulatory stage

Figure 26: Antibody deal upfront payment distribution, US$million – marketed stage

Figure 27: Summary median upfront payments by stage of development, 2007-2011

Figure 28: Antibody deals with milestone payments

Figure 29: Oncology deals with royalty rates, %

Figure 30: Antibody deal royalty rate distribution, US$million – discovery stage

Figure 31: Antibody deal royalty rate distribution, US$million – preclinical stage

Figure 32: Antibody deal royalty rate distribution, US$million – phase I stage

Figure 33: Antibody deal royalty rate distribution, US$million – phase II stage

Figure 34: Antibody deal royalty rate distribution, US$million – phase III stage

Figure 35: Antibody deal royalty rate distribution, US$million – regulatory stage

Figure 36: Antibody deal royalty rate distribution, US$million – marketed stage

Figure 37: Summary median royalty rate by stage of development, 2007-2011

Figure 38: Top antibody deals by value since 2007

Figure 39: Top antibody deals signed by bigpharma value since 2007

Figure 40: Recent deals (Jan 2007 to Feb 2012) - By therapy area (Cardiovascular)

Figure 41: Recent deals (Jan 2007 to Feb 2012) - By therapy area (Central Nervous System)

Figure 42: Recent deals (Jan 2007 to Feb 2012) - By therapy area (Dermatology)

Figure 43: Recent deals (Jan 2007 to Feb 2012) - By therapy area (Gastrointestinal)

Figure 44: Recent deals (Jan 2007 to Feb 2012) - By therapy area (Genetic disorders)

Figure 45: Recent deals (Jan 2007 to Feb 2012) - By therapy area (Genitourinary)

Figure 46: Recent deals (Jan 2007 to Feb 2012) - By therapy area (Hematology)

Figure 47: Recent deals (Jan 2007 to Feb 2012) - By therapy area (Hormonal)

Figure 48: Recent deals (Jan 2007 to Feb 2012) - By therapy area (Hospital care)

Figure 49: Recent deals (Jan 2007 to Feb 2012) - By therapy area (Immunology)

Figure 50: Recent deals (Jan 2007 to Feb 2012) - By therapy area (Infectives)

Figure 51: Recent deals (Jan 2007 to Feb 2012) - By therapy area (Inflammatory)

Figure 52: Recent deals (Jan 2007 to Feb 2012) - By therapy area (Metabolic)

Figure 53: Recent deals (Jan 2007 to Feb 2012) - By therapy area (Musculoskeletal)

Figure 54: Recent deals (Jan 2007 to Feb 2012) - By therapy area (Oncology)

Figure 55: Recent deals (Jan 2007 to Feb 2012) - By therapy area (Ophthalmics)

Figure 56: Recent deals (Jan 2007 to Feb 2012) - By therapy area (Respiratory)

Figure 57: Online partnering resources

Figure 58: Forthcoming partnering events

Figure 59: Deal type definitions

Figure 60: Collaborative R&D agreement for BiTE antibodies against three undisclosed solid tumor targets

To order this report:Biopharmaceutical Industry: Antibody Partnering Terms and Agreements

More  Market Research Report

Check our  Industry Analysis and Insights

Nicolas Bombourg

Reportlinker

Email: [email protected]

US: (805)652-2626

Intl: +1 805-652-2626

SOURCE Reportlinker

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