"Doctors have been trying to manage genital herpes for 30 years with acyclovir-like antiviral drugs, and the approach has not stopped the spread of herpes," says Dr. Halford. "Over one million people per week continue to be newly infected with HSV-1 or HSV-2. It is time to offer herpes sufferers a 21st century solution with the potential to not only better treat herpes, but to simply stop the spread of the disease."
In the United States, one out of six people aged 14 to 49 have genital herpes. Aside from genital herpes, HSV-1 is a major cause of blindness and life threatening encephalitis – or inflammation of the brain. Neonatal herpes, a life-threatening complication that occurs when babies contract HSV-1 or HSV-2 from their mothers during childbirth, is also a major concern. The World Health Organization has called for better herpes prevention strategies, as people with genital herpes are three times more likely to contract HIV/AIDS.
Currently the only FDA-approved treatment for herpes is antiviral drugs, and the results of the Phase I TheravaxHSV-2 vaccine trial suggests that this therapeutic HSV-2 vaccine may offer sufferers with a more effective treatment option. Rational Vaccines has licensed the patents upon which the live TheravaxHSV-2 vaccine is based and has also licensed a superior antibody test called the "HSV ABVIC" test which measures HSV Antibody Binding to Virus-Infected Cells.
"This is a very exciting time when it comes to medical innovations. Dr. Halford has created a safe and effective vaccine. Eradicating the HSV pandemic in our lifetime is within our grasp," says Agustin Fernandez III, CEO of Rational Vaccines. "Dr. Halford's research and our company's recent clinical trial have opened the door to a better world where herpes no longer has to be suffered in silence, but can be treated and prevented."
Rational Vaccines is continuing to monitor the HSV-2 symptoms in clinical trial participants and is taking further steps to advance its live TheravaxHSV-2 vaccine from the laboratory to the clinics. For more information, please visit www.rationalvaccines.com.
About Dr. William Halford, Ph.D.
William Halford Ph.D., received his Ph.D. from the Louisiana State University Medical Center, New Orleans in 1996, performed his postdoctoral training at the University of Pennsylvania and joined the faculty of Tulane University Health Science Center in 2000. Dr. Halford accepted his current position as an Associate Professor in the Department of Medical Microbiology & Immunology at Southern Illinois University in 2007. His research has focused on the biology that explains how herpes simplex virus (HSV) alternates between latent and active infections. Dr. Halford has authored more than 50 peer-reviewed publications, reviews, book chapters, and patents, which focus on HSV biology and practical applications of this knowledge.
About Rational Vaccines
Rational Vaccines (RVx) was formed in 2015 for the purpose of offering better solutions to stop the spread of herpes and alleviate the problems faced by people suffering with unrelenting, chronic disease. All research and trials are led by Dr. William Halford, PhD. For more information please visit www.rationalvaccines.com.
To view the original version on PR Newswire, visit:http://www.prnewswire.com/news-releases/first-ever-human-trial-of-a-live-attenuated-functioning-therapeutic-herpes-vaccine-300345431.html
SOURCE Rational Vaccines