NEW YORK, March 5, 2012 /PRNewswire/ -- Reportlinker.com announces that a new market research report is available in its catalogue:
Global Genetic Engineering Industry
http://www.reportlinker.com/p0152432/Global-Genetic-Engineering-Industry.html#utm_source=prnewswire&utm_medium=pr&utm_campaign=Genetical
The global outlook series on Genetic Engineering provides a collection of market briefs and concise summaries of research findings. The report offers an aerial view of the industry, highlights latest developments, and discusses demand drivers, issues and concerns, and regulatory environment. Discussion on the industry's most noteworthy regional market, the US, is amply detailed with unbiased research commentary to provide the reader a rudimentary understanding of the prevailing market climate. Market discussions in the report are punctuated with fact-rich market data tables. Regional markets elaborated upon include United States, Canada, India, China, and South Africa among others. Also included is an indexed, easy-to-refer, fact-finder directory listing the addresses, and contact details of 153 companies active in the market.
1. INDUSTRY OVERVIEW 1Genetic Engineering: A Prelude 1Genetic Engineering: Not the Same As Biotechnology 1The Evolution and Progress of GM Crops 2M Crops Gain Global Acceptance 2GM Cultivation Gains Prominence in Developing Nations 2Rising Prices, Food Shortage Make Biotech Grains Attractive 2Socio-Economic Impacts of Biotech Crops 3Impact of GM Crops on Biodiversity 3Challenges to GM Crops Adoption 3Biotech Regulatory Measures Hinder Crop Domestication 4Genetic Modification of Forest Trees and Associated Issues 4Biosafety: a Key Criterion Associated 4Governments Not to Give Up on GM Hope 4US - The Largest Producer of GM Crops 5Leading Countries by Biotech Crop Area (2009) 5Table 1: Current and Future Analysis of the Global BiotechCrops Market By Geographic Region for the US, Canada,Asia-Pacific, Latin America and Rest of World IndependentlyAnalyzed with Annual Sales Figures in US$ Million for 2010through 2015 6Major Market Participants 7
2. MARKET DYNAMICS 8
Global Food Demand to Drive Need for GM Crops 8
Developing Countries: Major Share Holders for Biotech Crop
Production 8
Status of Biotech Rice in the World 8
Genetic Engineering - A Solution for Food Crisis! 9
Harmful or Healthy: Breaking The Myth About GM Crops 9
Non-food Sectors to Benefit from GE Technology 9
Genetic Engineering and Enzymes 9
GE to Help Starch and Sugar Processing Enzyme Market 10
GE to Drive Demand for Bakery Enzymes 10
Genetic Engineering Revolutionizes Vaccines 10
Plant Expression Systems to Replace Traditional Expression
Systems 11
Approved Gene Therapies Fail to Gather Momentum 12
P53 Gene Therapy - A Novel Approach in Cancer Treatment 12
3. ISSUES AND CONCERNS 13The GM Food Issue Continues 13Nations at Crossroads to Accept or Object GE Crops 13Nations Set Global Agenda to Settle GM Crop Controversies 14Challenges Confronting the Biotechs 14Efficacy - The Key Challenge for Gene Therapy 14Key Factors Affecting the Indian Biotechnology Industry 15
4. REGIONAL TRENDS 16
Genetic Engineering: A Fast Catching Trend in Developing
Countries 16
Future of GE Technologies 17
US: Owns a Lion's Share of the World Biotech Produce 17
Table 2: US Biotech Crop Produce By Year in Millions of
Hectares 17
GM Crops Fail to Live up to Expectations in the US 18
US Soybean and Corn Crop to Witness Robust Growth 18
FDA Compliance to Spur Growth in the US Biotech Industry 18
Canada Reaches Million Acres Mark 18
Table 3: Canadian Biotech Crop Produce by Leading Crops
(2011) 19
Table 4: Biotech Maize in Canada: Percentage Share Breakdownby Varieties with Single Stacked gene, Two Stacked genes, andTriple Stacked genes (2011) 19Small and Medium Sized Biotech Enterprises to Grow in Europe 19Germany and UK- The Hub of European Gene Therapy Market 20Spain Garners Leading Spot in Europe's GM Maize Market 20Table 5: Biotech Maize Hectarage in Europe (2011) 20GMO Crops' Future Hinges on Co-Existence Measures in EU 21European Commission Downplays Impact of GM Crops 21Biotech Crops Remain in a Political Standstill in Europe 21European Nations Ban GM Potato and Maize 21UK Government's GM Crops Proposal Faces Rebuff 22Spanish Transgenic Corn Plantation Increases 22Ireland: A GM-free Zone 22Gene Therapy Pipeline Strengthens in Asia 23GM Foods Trends in Asia 23Bt Cotton Fails in Asia 24Chinese Biopharmaceutical Market to Continue its Growth Spurt 24Government to Support Biopharmaceutical Innovation 24Biotech Crop Research Gains Momentum in India 25The Great Indian Bt Brinjal Controversy 25India - The Leading Cultivator of Bt Cotton 25India Ousts China in Bt Cotton Cultivation 25Indian Agri-Bio Industry on a Roll 26India: Ban on Genetically Engineered Crops? 26Legalization of Genetic Engineering in Indonesia 26GM Crops to Earn Good Returns for Australia 26Biotechnology - A Boon for Agriculture in Malaysia 27Poor Biotech Crops Adoption in Africa 27Biotech Crops Cultivation Zooms in South Africa 27Table 6: Percentage Share Breakdown of Biotech Maize by Type(2011) in South Africa 28
Table 7: Percentage Share Breakdown of Biotech Cotton by Type
(2011) in South Africa 28
Uruguayan Community Resist GM Plants 28
GM Crop Adoption Rate Grows Exponentially in Brazil 28
5. GENETIC ENGINEERING: AN OVERVIEW 29The Concept 29Molecular Basics - The Gene 30Genome - The Information Pool 30Evolution of Genetic Engineering 30Historical Developments in Genetic Engineering: 31The Human Genome Project 31Significant Events in the Past 32Gene Therapy 32Types of Gene Therapy 33Monogenic Gene Therapy 33Suicide Gene Therapy 33Antisense Gene Therapy 33Human Genetic Engineering 33Genetic Engineering in Animals 33Role of Biotechnology in Agriculture 34Insect Resistant Crops Vs. Herbicide Tolerant Crops 34Some Interesting GM Crop Facts 35Myths and Fads Associated to Genetically Engineered Crops 35Improvement of Genetic Characters in Wheat 36Agrobacterium tumifaciens Mediated Transformation 36The Biolistic Transformation Method 37Genetically Modified Foods 37GM Food Faces Worldwide Criticism During Initial Years 37Benefits of Genetically Modified Foods 38Pest Resistance 39Cold Tolerance 39Herbicide Tolerance 39Drought and Salinity Tolerance 39Disease Resistance 39Phytoremediation 40Nutrition 40Pharmaceuticals 40Negative Impacts of GM Foods 40Possibility of Crosspollination 40Decreased Pesticides Effectiveness 40Unintentional Destruction of Other Species 41Health Concerns Related to GM Foods 41Cost Concerns Related to GM Foods 41Genetic Engineering and Food Processing 42Genetic Engineering and Regulatory Environment 42Patents - An Overview 43
6. GENE THERAPY - A REVIEW 44
Factors Influencing Gene Therapy's Future Development 44
Human Genome Analysis 44
Gene Therapy - The Next Generation Cardiovascular Therapy 44
Public Support for Gene Therapy 44
RNAi Bode Bright Prospects 44
Factors Hampering Gene Therapy Future Development 45
Stringent US and European Regulatory Laws Prolongs Gene
Therapy Development 45
Identifying Genetic Fault 45
Immune Response 45
Delivering Genetic Materials into Patient Cells 45
Multigene Disorders 46
Side Effects 46
Push Towards Germline Gene Transfer 46
Technical Limitations 46
Commercialization: A Road Uphill 47
Time Line in Gene Therapy Drug Development 47
Table 8: Gene Therapy Clinical Trials (2011): Percentage
Breakdown by Geographic Region for the US, Europe, Canada,
Japan and Rest of World 47
Table 9: Gene Therapy Clinical Development (2011):Percentage Share Breakdown by Stage 48Select Gene Therapy Products in Phase III Development (2010) 48Select Gene Therapy Products in Phase II Development (2010) 49Select Gene Therapy Products in Phase I and Pre-ClinicalDevelopment (2010) 49Target Diseases and Players Involved 50Key Players by Application Area 50Table 10: Clinical Development of Gene Therapy by TargetedIndication (2011): Percentage Breakdown of Number of Trialsfor Cancer Diseases, Cardiovascular Diseases, InfectiousDiseases, Monogenic Diseases, Neurological Diseases andOthers 50
Table 11: Gene Therapy Clinical Trials Worldwide (2011):
Percentage Breakdown by Gene Type Transferred - Antigen,
Cytokine, Tumor Suppressor, Growth Factor, Deficiency,
Suicide, and Others 51
Table 12: Gene Therapy Clinical Development by Vectors Used(2011): Percentage Breakdown of Number of Trials forAdenovirus, Retrovirus, Plasmid DNA, Vaccinia Virus,Lipofection and Others 51Gene Therapy Industry in Europe and the US - A Comparison 51
7. GENE AMPLIFICATION TECHNOLOGY 53
Definition of Gene Amplification 53
Target vs. Signal Amplification 53
Available Types of Gene Amplification Technologies 53
Polymerase Chain Reaction 53
The PCR comprises four major components: 53
Reagents and Equipment Required for PCR 54
Reaction Steps 54
Denaturation 54
Annealing 54
Extension 54
Detection of Amplified Product/DNA 55
(Q&Q) PCR 55
Reverse Transcriptase PCR (RT-PCR) 56
Alternative Technologies to PCR 56
OmniPlex 56
Genome-wide disease association studies 56
Pharmacogenomics studies 56
Molecular diagnostics and forensics 56
Additional OmniPlex Applications in Development 56
Strand Displacement Amplification 57
Ligase Chain Reaction 57
LCR Involves a Cyclic two-Step Reaction 57
Gene Amplification Technology (GAT) 57
Hybrid Capture 57
Isothermal DNA Amplification Techniques 58
Rolling Circle Amplification in Diagnostics 58
Ican Isothermal Gene Amplification Technology 58
BioHelix HDA Technology 58
Other Amplification Technologies 58
Signal Amplification Technology 58
Transcription Mediated Amplification 59
DNA Cleavage-based Signal Amplification 59
Ramification Amplification Method 59
End Use Market Analysis 59
Medical and Diagnostics 59
Role of Amplification Technology in the Diagnoses of
Infectious Diseases 60
Diagnosis of Infectious Diseases by PCR 60
Detection of Antimicrobial Resistance 61
PCR Based Nucleic Acid Amplification for Detection of
Antimicrobial Agents 61
Nucleic Acid Amplification Testing (NAT) 61
Nucleic Acid Amplification Methods 62
DNA Amplification Technology in the Diagnosis of Infectious
Diseases 62
Advantages 62
Limitations 62
Forensic and Paternity Testing 62
Food Safety 63
Table 13: Current and Future Analysis for Global Gene
Amplification Technology Market by Segment Independently
Analyzed with Annual Sales Figures in US$ Million for 2010
Through 2015 64
Table 14: Global Gene Amplification Market (2012): PercentageBreakdown of Value Sales by Geographic Region- the US,Canada, Japan, Europe and Rest of World 64
8. RESEARCH AND DEVELOPMENT 65
9. MERGERS & ACQUISITIONS 70
10. RECENT INDUSTRY ACTIVITY 76
11. PRODUCT/SERVICE LAUNCHES 91GLOBAL DIRECTORY
To order this report:Genetically Modified Organism, GMO Industry: Global Genetic Engineering Industry
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Nicolas Bombourg
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