A New Study Addressing the Benefits of Using the SELPHYL® System with Fat Transfer Published in the American Journal of Cosmetic Surgery

WAYNE, N.J., March 12, 2012 /PRNewswire/ -- Aesthetic Factors, LLC, an emerging company focused on autologous, point-of-care systems in regenerative medicine, is pleased to announce that a study examining the efficacy of the SELPHYL® System used with fat grafting procedures has been published in Volume 29 Issue 1 of the American Journal of Cosmetic Surgery.

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SELPHYL® is an ultrapure Platelet-Rich Fibrin Matrix (PRFM) preparation. Using a small amount of the patient's own blood, the system isolates and prepares PRFM for injection back into the patient. SELPHYL® naturally produces and releases a host of biologic growth factors that have been shown to promote tissue regeneration.

In the study entitled, "Benefits of Autologous Fat Grafting Using Fat Mixed with Platelet-Rich Fibrin Matrix (PRFM) SELPHYL®," Lead Researcher, Richard Goldfarb, MD, FACS Center for Smartlipo
Langhorne, PA analyzed the potential of SELPHYL® to increase vascularity in fat transfer – thus improving longevity potential. Fat grafting is used for facial rejuvenation, primarily to smooth out wrinkles and restore volume to areas of the face that have been deflated over time. However, historically, the long-term survival rates of autologous fat grafting have been variable. Consequently, fat grafting does not always produce the long-term correction for which patients are looking. The duration of fat transfer alone varies considerably, lasting anywhere from 6 months to several years.

The study follows a 37-year-old female who had fat from her outer thighs injected into her lower abdominal area. In one site on her lower abdomen, 8ccs of fat was injected; in another site, 8ccs of fat combined with 4ccs of SELPHYL® was injected. After eight weeks, the tissue was analyzed, showing viable fat in both sites, but the area injected with SELPHYL® showed an increase in blood vessels, which is key to improving the chances of long-term fat survival. The researchers concluded that the fat mixed with SELPHYL improved fat cell survival.

"After 3 to 16 months of consistent follow-up, outcomes reflect that SELPHYL® has given fat grafts not only a higher rate of permanency, but also a greater take rate," commented researcher Aaron L. Shapiro, M.D., a facial plastic surgeon in Bryn Mawr, PA.  "SELPHYL® has been easy to use and patients have been very pleased with their results. Preliminary findings reflect that the addition of SELPHYL® enhances and improves the long-term survival of my fat grafts."

"Any technique or mechanism that demonstrates efficacy in enhancing the graft survival would be very beneficial in cosmetic surgery. We are confident that this important clinical finding will lead to wider acceptance of the SELPHYL® plus fat technique," writes Dr. Goldfarb.

SELPHYL® is only available through qualified healthcare practitioners. Over 350 physicians and clinics worldwide currently feature the SELPHYL® System.

SOURCE Aesthetic Factors, LLC