CARTHAGE, Mo., Aug. 23, 2016 /PRNewswire/ -- Stratum Nutrition and joint-venture partner, ESM Technologies, the manufacturer of innovative, commercialized eggshell and eggshell membrane wellness ingredients, are pleased to announce a new canine study has published in the journal, Veterinary Medicine: Research & Reports, evaluating their joint health ingredient, NEM® brand eggshell membrane.
This 6-week, multi-center, randomized, double-blind, placebo-controlled trial was conducted at eight different veterinary clinics to evaluate NEM's efficacy, safety and tolerability in the treatment of sub-optimal joint function in dogs. Fifty-one privately-owned dogs having mild to moderate persistent sub-optimal joint function (e.g. difficulty in getting up from a laying position, a noticeable limp, impaired gait, difficulty in climbing stairs, etc.) received either oral NEM®, 6 mg/lb. (~13.5 mg/kg) or placebo once daily for 6 weeks. Changes in joint function, joint pain, and quality of life in the NEM® group versus the placebo group were evaluated by both dog owners and veterinarians via either the validated Canine Brief Pain Inventory (CBPI) (owner assessment, 1 week & 6 weeks) or Veterinary Canine Scoring Assessments (VCSA) (veterinarian assessments, 6 weeks). Additionally, changes in serum levels of the cartilage degradation biomarker, CTX-II, were also evaluated at 6 weeks.