Acquisition of Certain Cellumen Assets by Apredica

Combination expands Apredica's in the fast-growing predictive Toxicology market

Aug 05, 2010, 04:55 ET from Apredica

WATERTOWN, Mass., Aug. 5 /PRNewswire/ -- Apredica LLC ("Apredica"), a Contract Research Organization (CRO) specializing in the preclinical ADME(1) assessment of drug candidates and Toxicology assessment, announces that it has acquired the intellectual property and all other assets necessary for offering the Cellular Systems Biology and High Content Toxicology services previously offered by Cellumen, Inc.  

Background on Apredica

Apredica, based in Watertown, Massachusetts, near Boston, U.S., was founded in 2006 and provides preclinical contract testing services for the evaluation and optimization of the ADMET and pharmacokinetic properties of drug candidates early in the drug discovery process.  

Since its founding, Apredica has grown rapidly.  Its 2009 annual growth rate was 86%.  Apredica has 173 customers, mostly in the U.S., but including customers from Europe, East Asia, South Asia, Africa, South America, and Australia.  In 2009, 81% of Apredica's revenues came from repeat customers, while Apredica acquired 56 new customers.  All of Apredica's scientists have more than 10 years' drug-discovery experience and 80% of them have Ph.D.s.  

Background on Cellumen

Cellumen is the inventor of the Cellular Systems Biology (CSB™) approach to in vitro discovery and toxicology.  CSB analyzes the system's response of cell and organ models to drug treatments.  This research has led to the creation of Cellumen's Intellectual Property for next-generation reagents and multiplexed assays using the High Content Screening (HCS) technology platform.  CSB™ is an extensively validated approach that has been co-developed by Cellumen with external pharmaceutical and government partners.  

The acquisition of Cellumen's assets and commercial offering significantly strengthens Apredica's existing High Content Toxicology offerings.  

Dr. Katya Tsaioun, Chief Executive Officer of Apredica, said:

"I am looking forward to leading the Company's scientific growth into the in vitro toxicology market, where rapid scientific advances are now being made by pioneers in the field such as Cellumen.  Such technologies simultaneously improve our ability to detect mechanisms of human toxicity, reduce the time and cost of developing safe and efficacious drugs, and pave the way towards developing toxicology models that are more predictive of human biology than currently available models.  As human-biology-based models improve, they will reduce and ultimately replace animal toxicology models."


  1. ADME is an acronym for the Absorption, Distribution, Metabolism, and Elimination of xenobiotics (chemicals such as drugs which may be introduced into an organism but which are not normally produced or expected to be present in the organism).  ADMET and ADME Tox are acronyms for ADME and Toxicity.

For further information contact Apredica LLC

Dr. Katya Tsaioun, Chief Executive Officer

Tel: +1 617-812-1911

Mr. Douglas Bates, Chief Business Officer

Tel: +1 781-679-2172

SOURCE Apredica