NEW YORK, April 10, 2014 /PRNewswire/ -- Actinium Pharmaceuticals, Inc. (NYSE MKT: ATNM), is an emerging biopharmaceutical company focused on the $54 billion market for cancer drugs. The Company's most advanced products are Actimab™-A, an antibody-drug construct containing actinium 225 (Ac-225), currently in human clinical trials for acute myeloid leukemia (AML) and Iomab™-B, an antibody-drug construct containing iodine 131 (I-131), used in myeloconditioning for hematopoietic stem cells transplantation (HSCT) in various indications.
Actinium develops drugs for treatment of cancer intended to cure or significantly improve survival of the affected patients with lower side effect profiles. Products currently under development include monoclonal antibodies labeled with radioisotopes. The Company's APIT technology is based on attaching actinium 225 (Ac-225) or bismuth 213 (Bi-213) alpha emitting radioisotopes to monoclonal antibodies. Alpha emitting radioisotopes are unstable chemical elements that decay by releasing alpha particles. Alpha particles can kill any cell in whose immediate proximity they are released It is crucial for the success of these drug candidates to contain monoclonal antibodies that can successfully seek cancer cells and can kill them with the attached isotope while not harming nearby normal cells.
As with many cancer sub-categories there is a large available market with very few treatment alternatives particularly for ATNM's older target patients. ATNM's novel approach has no clear direct competition and has the potential to be disruptive in the market.
The Company has recently filed its FY2013 Form 10K annual financial report and related disclosures which provide an update on operating considerations and the latest financial information for investors.
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