Cell Culture: The World Market for Media, Sera and Reagents, 3rd. Edition

NEW YORK, Oct. 11, 2011 /PRNewswire/ -- Reportlinker.com announces that a new market research report is available in its catalogue:

Cell Culture: The World Market for Media, Sera and Reagents, 3rd. Edition

http://www.reportlinker.com/p0652511/Cell-Culture-The-World-Market-for-Media-Sera-and-Reagents-3rd-Edition.html#utm_source=prnewswire&utm_medium=pr&utm_campaign=In_Vitro_Diagnostic

Several cell culture-derived biopharmaceutical drugs were launched in the US and European markets in 2010. Biopharmaceuticals (recombinant proteins, monoclonal antibody and nucleic acid-based products) represent the fastest growing sector in the pharmaceutical industry. Driving the extraordinary interest in biopharmaceuticals is the ability of these large proteins to target diseases in a very specific manner, thus maximizing efficacy while minimizing side effects.

Growth in the development and production of biopharmaceuticals is the most significant driver of the cell culture market. Biological products are developed from large and complex protein molecules, which require equally complex manufacturing methods and an array of analytical techniques. Protein-based biopharmaceuticals are invariably produced by an initial cell culture step (upstream processing), followed by product recovery, purification and formulation into final product format (downstream processing).

This report analyzes the world market for the cell cultures used in these steps and the major trends driving this market. Forecasts and current market sizing are provided in three specific segments:

  • Media,
  • Sera, and
  • Reagents

In addition to a thorough discussion of the technologies and techniques currently employed and emerging in the cell culture area, the Kalorama's exhaustive report provides specific information on:

  • Market Size, growth, and forecasts of the segments through 2015
  • Competitive Market Share by leading supplier as of 2010.
  • Estimated Market Share by Region (North America, Europe, U.S.)
  • Key Market Drivers and Restraints for suppliers, including discussions of biopharmaceutical pipelines, biomedical R&D directions, and the future of transgenic plant and animal production.
  • Review of the various expression systems (Bacteria, Yeast, Insect, and Mammal) and the biopharmaceutical product manufactured by these systems
  • Discussion of the preferences in media types vying for dominance in the market, including the following:

    • ADCF - animal derived component free media
    • CD - chemically defined media
    • CSFM - complete serum free medium
    • PF - protein free media
    • SF - serum free media
    • SFM - serum free medium

CHAPTER ONE: EXECUTIVE SUMMARY

Scope and Methodology

Cells for Biopharmaceutical Production

Bacteria and Yeasts Systems

Animal Cell Systems

Insect Cell Systems

Cell Lines and Cell Banks

Fermentors and Bioreactors

Stirred-Tank Reactors

Airlift Fermentors

Packed Bed Reactors

Hollow-Fiber Reactor

Disposable Systems

Fermentation Processes

Batch and Fed-Batch Fermentation

Suspended vs. Anchored Cells

Microencapsulation

Cell Culture Environment

Functions and Components of Basal Media

pH and Osmotic Pressure

Energy Sources

Nutrients

Cell Culture Media

Lysogeny broth (LB)

Classical Media

Serum-free Media

Protein-Free Media

Chemically Defined Media

Specialty Media

Sera

Reagents

Shifting Towards Non-animal Derived Reagents

Addressing Reagent Safety Issues

World Cell Culture Market

Cell Culture Market and Forecast

Current and Future Trends

CHAPTER TWO: GENETICALLY MODIFIED CELLS FOR BIOPHARMACEUTICAL DEVELOPMENT

Growing Demand for Biopharmaceuticals

Biopharmaceutical Market

Development of Biopharmaceuticals

Biopharmaceutical Product Approvals

Biopharmaceutical Growth Increases Demand for Cell Culture Products

A Brief History of Biotechnology

Science of Genetic Manipulation

From Petri Dish to Biopharmaceutical Upstream Bioprocessing: Cell Culture Expression Systems

Cells for Biopharmaceutical Production

Bacteria and Yeasts Systems

Animal Cell Systems

Insect Cell Systems

Advantages/Disadvantages of Cell Culture Systems

Cell Lines and Cell Banks

Biopharmaceuticals Produced from Cell Culture

Cell Culture Practices and Regulatory Guidelines

Validation of Facilities

Maintaining Sterilization Standards

CHAPTER THREE: CELL CULTURE TECHNOLOGY

Introduction and Overview

Milestones in Cell Culture Development

Cell Lines for Bioproduction

Predominant Cell Lines

Chinese Hamster Ovary (CHO)

SP2/0, and NS0

HEK 293 and PER. C6

Sources: Largest Collections of Cell Lines

Fermentors and Bioreactors

Types of Bioreactors/Fermentors

Stirred-tank Reactors

Airlift Fermentors

Packed Bed Reactors

Hollow-fiber Reactor

Disposable Systems

Fermentation Processes

Batch and Fed-Batch Fermentation

Suspended vs. Anchored Cells

Microencapsulation

Cell Culture Environment

Functions and Components of Basal Media

pH and Osmotic Pressure

Energy Sources

Nutrients

Cell Culture Media

Types of Media

Lysogeny broth (LB)

Classical Media

Serum-free Media

Protein-free Media

Chemically Defined Media

Specialty Media

Sera

Sources of Sera

Bovine Serum Safety Issues and Regulations

Shift to Serum-free Media

Reagents

Major Types of Biologic Reagents

Amino Acids

Growth Factors and Cytokines

Albumin

Transferrin

Thrombin

Growth Supplements

Protease Inhibitor

Attachment Factors

Shifting Towards Non-animal Derived Reagents

Addressing Reagent Safety Issues

CHAPTER FOUR: CELL CULTURE MARKET; CURRENT AND FUTURE TRENDS

Overview

Cell Culture Market

Market Drivers

Cell Culture Market Forecast

Segment Analysis

Media

Sera

Reagents

Cell Culture Suppliers' Market Share

current and future trends

Shift to Serum-free and Animal Product-free Media

Concomitant Need for Animal-derived Media

Cell Culture-based Vaccine Production

Cell Culture-based Vaccine on Market

Stem Cell Research Driving Cell Culture Market

Life Technologies

Sigma-Aldrich

ThermoFisher Scientific

Lonza Bioscience

EMD Millipore

BD Bioscience

Impact of Generic Biopharmaceuticals on Cell Culture Market

Impact of Transgenic Animals and Plants on the Cell Culture Market

CHAPTER FIVE: COMPANY PROFILES

Advanced Biotechnologies, Inc.

History and Lines of Business

Cell Culture Products and Services

Affymetrix, Inc.

History and Lines of Business

Cell Culture Products

Molecular Biology Enzymes

Molecular Biology Kits and Reagents

Purification

Biochemicals

PCR Reagents

Financial Information

AMRESCO, Inc.

History and Lines of Business

Cell Culture Products

Analytical Biological Services Inc.

History and Lines of Business

Cell Culture Products

Mammalian Cell Culture

Cell in Microtiter Plates for HTS

Primary Cultures

Insect Cell Culture

Athena Enzyme Services

History and Lines of Business

Cell Culture Products

Atlanta Biologicals, Inc.

History and Lines of Business

Cell Culture Products

Animal & Human Sera

Media & Balanced Salts

Supplements & Reagents

Cell Separation Products

BD Biosciences

History and Lines of Business

Cell Culture Products

Financial Information

BIOCHROM AG

History and Lines of Business

Cell Culture Products

Bioreclamation Inc

History and Lines of Business

Cell Culture Products

Cell Essentials, Inc.

History and Lines of Business

Cell Culture Products

CellGenix Technologie Transfer GmbH

History and Lines of Business

Cell Culture Products and Services

ClonTech Laboratories, inc.

History and Lines of Business

Cell Culture Products

EMD Millipore

History and Lines of Business

Cell Culture Products

Financial Information

Gemini Bio-Products

History and Lines of Business

Cell Culture Products

Cell Culture Sera

Human Sera

Specialized Media

Irvine Scientific

History and Lines of Business

Cell Culture Products

Cell Culture Products

Custom Media Program

Express Media Service

R&D Development Program

Invitria

History and Lines of Business

Cell Culture Products

Cellastim

Lacromin

Optiferrin

ITSE Animal-free

Zap-CHO

Zap-Hybridoma

J R Scientific, Inc.

History and Development

Cell Culture Products

Life Technologies Corporation

History and Lines of Business

Cell Culture Products

Financial Information

Lonza Bioscience

History and Lines of Business

Cell Culture Products and Services

Culture Media Development

Cell Line Creation

Cell Banking

Financial Information

Mediatech, Inc.

History and Lines of Business

Cell Culture Products

MP Biomedicals

History and Lines of Business

Cell Culture Products

Novozymes Biopharma US Inc

History and Lines of Business

Cell Culture Products

rAlbumin

Albucult

Albufuse and Albufuse Flex

Yeast Expression Technology

Growth Factors

Bacillus-derived Hyaluronic Acid

Purification Ligands

Recombinant Tansferrin

PAA labORATORIES, Inc.

History and Lines of Business

Cell Culture Products

PromoCell GmbH

History and Lines of Business

Cell Culture Products

Quality Biological, Inc.

History and Lines of Business

Cell Culture Products

R&D Systems, Inc.

History and Lines of Business

Cell Culture Products

SAFC Biosciences

History and Lines of Business

Cell Culture Products

Financial Information

SBH Sciences

History and Lines of Business

Cell Culture Products

Selexis SA

History and Lines of Business

Cell Culture Products

SeraCare Life Sciences, Inc.

History and Lines of Business

Cell Culture Products

Financial Information

Sera Laboratories International Ltd

History and Lines of Business

Cell Culture Products

Product Categories

Thermo Fisher Scientific, Inc.

History and Lines of Business

Cell Culture Products

Financial Information

Wisent, Inc.

History and Lines of Business

Cell Culture Products

LIST OF EXHIBITS

CHAPTER ONE: EXECUTIVE SUMMARY

Exhibit 1-1

Worldwide Cell Culture Market

Exhibit 1-2

Cell Culture World Market Share, by Region, 2010

CHAPTER TWO: GENETICALLY MODIFIED CELLS FOR BIOPHARMACEUTICAL DEVELOPMENT

Exhibit 2-1

Biopharmaceutical Development by General Indication and Development Activity (Phase III through Registration)

Exhibit 2-2

Biopharmaceuticals Approved in the US and/or the EU, 2010

Exhibit 2-3

Approximate times from Introduced Gene to Protein Production at Useable Levels

Exhibit 2-4

Disadvantages/Advantages of Cell Culture Systems

Exhibit 2-5

Selected Biopharmaceuticals Produced from Bacteria, Yeast and Mammalian Cells

CHAPTER THREE: CELL CULTURE TECHNOLOGY

Exhibit 3-1

Selected Products/Companies Offering Alternatives to Animal Sera Products for Hybridoma, Myeloma and CHO cell lines

CHAPTER FOUR: CELL CULTURE MARKET; CURRENT AND FUTURE TRENDS

Exhibit 4-1

Worldwide Cell Culture Market, 2005-2015

Exhibit 4-2

Cell Culture World Market Share, by Region, 2010

Exhibit 4-3

World Cell Culture Market by Segment: Media, Sera and Reagents, 2005-2015

Exhibit 4-4

Cell Culture Market Share, 2010

Exhibit 4-5

Selected Transgenic Products in Clinical Trials

To order this report:

In Vitro Diagnostic Industry: Cell Culture: The World Market for Media, Sera and Reagents, 3rd. Edition

In Vitro Diagnostic Business News

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Nicolas Bombourg

Reportlinker

Email: nbo@reportlinker.com

US: (805)652-2626

Intl: +1 805-652-2626

SOURCE Reportlinker



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